PDIA3 ELISA Kit for Human(Homo sapiens) | EIAab.comPDIA3 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > PDIA3(Gene name) > Human

PDIA3 (Gene name),

Protein disulfide-isomerase A3 (Protein name ), PDIA3_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PDIA3(ERP57;ERP60;GRP58);

Protein name:

Protein disulfide-isomerase A3;

Alternative:

58 kDa microsomal protein(p58);58 kDa glucose-regulated protein;Endoplasmic reticulum resident protein 57(ER protein 57;ERp57);Disulfide isomerase ER-60;Endoplasmic reticulum resident protein 60(ER protein 60;ERp60);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Subunit of the TAP complex, also known as the peptide loading complex (PLC). Can form disulfide-linked heterodimers with TAPBP. Interacts with ERP27 and CANX.

Function:

Subcellular Location:

Endoplasmic reticulum lumen Melanosome Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Protein Attributes:

Sequence length:

505

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

505:

AQEDL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P30101

KEGG:

hsa:2923

UniGene:

Hs.591095

STRING:

9606.ENSP00000300289

MIM:

602046

Pfam:

PF00085

String:

P30101

Uniprot:

P30101

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ELISA Kit for Human Protein disulfide-isomerase A3

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E1497m

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ELISA Kit for Human Protein disulfide-isomerase A3

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E1497b

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96T

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ELISA Kit for Human Protein disulfide-isomerase A3

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E1497h

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ELISA Kit for Human Protein disulfide-isomerase A3

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E1497r

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96T

ELISA Kit for Human Protein disulfide-isomerase A3

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E1497c

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96T

CLIA Kit for Human Protein disulfide-isomerase A3

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U1497r

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96T

CLIA Kit for Human Protein disulfide-isomerase A3

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U1497c

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96T

CLIA Kit for Human Protein disulfide-isomerase A3

Cat.:

U1497m

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MSDS:

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Packing:

96T

CLIA Kit for Human Protein disulfide-isomerase A3

Cat.:

U1497b

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Packing:

96T

CLIA Kit for Human Protein disulfide-isomerase A3

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U1497h

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Polyclonal Antibody for Human Protein disulfide-isomerase A3

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P1497Rb-h

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40ug/0.2ml

Polyclonal Antibody for Human Protein disulfide-isomerase A3

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P1497Rb-r

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Polyclonal Antibody for Human Protein disulfide-isomerase A3

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P1497Rb-m

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Polyclonal Antibody for Human Protein disulfide-isomerase A3

Monoclonal Antibody for Human Protein disulfide-isomerase A3

Protein for Human Protein disulfide-isomerase A3

R&D Technical Data

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Precision

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Recovery

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Linearity

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References

1.

"Molecular cloning and characterization of a cDNA for bovine phospholipase C-alpha: proposal of redesignation of phospholipase C-alpha."
Hirano N. , Shibasaki F. , Katoh H. , Sakai R. , Tanaka T. , Nishida J. , Yazaki Y. , Takenawa T. , Hirai H.
Biochem. Biophys. Res. Commun.204:375-382(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"cDNA cloning and baculovirus expression of the human liver endoplasmic reticulum P58: characterization as a protein disulfide isomerase isoform, but not as a protease or a carnitine acyltransferase."
Bourdi M. , Demady D. , Martin J.L. , Jabbour S.K. , Martin B.M. , George J.W. , Pohl L.R.
Arch. Biochem. Biophys.323:397-403(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 25-36 AND 130-144;CATALYTIC ACTIVITY
tissue: Liver.
3.

"ERp60 does not substitute for protein disulphide isomerase as the beta-subunit of prolyl 4-hydroxylase."
Koivunen P. , Helaakoski T. , Annunen P. , Veijola J. , Raeisaenen S. , Pihlajaniemi T. , Kivirikko K.I.
Biochem. J.316:599-605(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Heart.
4.

"Cloning, expression and genomic organization of human placental protein disulfide isomerase (previously identified as phospholipase C alpha)."
Charnock-Jones D.S. , Day K. , Smith S.K.
Int. J. Biochem. Cell Biol.28:81-89(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Placenta.
5.

"Structures of the human gene for the protein disulfide isomerase-related polypeptide ERp60 and a processed gene and assignment of these genes to 15q15 and 1q21."
Koivunen P. , Horelli-Kuitunen N. , Helaakoski T. , Karvonen P. , Jaakkola M. , Palotie A. , Kivirikko K.I.
Genomics42:397-404(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
6.

"Functions of characteristic Cys-Gly-His-Cys (CGHC) and Gln-Glu-Asp-Leu (QEDL) motifs of microsomal ER-60 protease."
Urade R. , Oda T. , Ito H. , Moriyama T. , Utsumi S. , Kito M.
J. Biochem.122:834-842(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 25-34 AND 504-505;MUTAGENESIS OF CYS-57; CYS-60; CYS-406 AND CYS-409
tissue: Liver epithelium.
7.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue: Liver.
tissue: Lung.
tissue: Lymph.
8.

"A two-dimensional gel database of human colon carcinoma proteins."
Ji H. , Reid G.E. , Moritz R.L. , Eddes J.S. , Burgess A.W. , Simpson R.J.
Electrophoresis18:605-613(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-54; 62-75 AND 95-104
tissue: Colon carcinoma.
9.

"Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides."
Gevaert K. , Goethals M. , Martens L. , Van Damme J. , Staes A. , Thomas G.R. , Vandekerckhove J.
Nat. Biotechnol.21:566-569(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-38
tissue: Platelet.
10.

"Human liver protein map: a reference database established by microsequencing and gel comparison."
Hochstrasser D.F. , Frutiger S. , Paquet N. , Bairoch A. , Ravier F. , Pasquali C. , Sanchez J.-C. , Tissot J.-D. , Bjellqvist B. , Vargas R. , Appel R.D. , Hughes G.J.
Electrophoresis13:992-1001(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 25-33
tissue: Liver.
11.

"Two-dimensional electrophoretic analysis of human breast carcinoma proteins: mapping of proteins that bind to the SH3 domain of mixed lineage kinase MLK2."
Rasmussen R.K. , Ji H. , Eddes J.S. , Moritz R.L. , Reid G.E. , Simpson R.J. , Dorow D.S.
Electrophoresis18:588-598(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 26-42
tissue: Mammary carcinoma.
12.

Lubec G. , Vishwanath V. , Chen W.-Q. , Sun Y.
Submitted (2008-12) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 63-73; 95-104; 108-129; 131-140; 259-271; 297-304; 306-329; 336-344; 352-362; 367-397; 434-460 AND 472-482;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Brain.
tissue: Cajal-Retzius cell.
tissue: Fetal brain cortex.
13.

"Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes."
Rasmussen H.H. , van Damme J. , Puype M. , Gesser B. , Celis J.E. , Vandekerckhove J.
Electrophoresis13:960-969(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 95-104 AND 472-479
tissue: Keratinocyte.
14.

"Cluster analysis of an extensive human breast cancer cell line protein expression map database."
Harris R.A. , Yang A. , Stein R.C. , Lucy K. , Brusten L. , Herath A. , Parekh R. , Waterfield M.D. , O'Hare M.J. , Neville M.A. , Page M.J. , Zvelebil M.J.
Proteomics2:212-223(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MASS SPECTROMETRY
tissue: Mammary cancer.
15.

"Proteomic analysis of early melanosomes: identification of novel melanosomal proteins."
Basrur V. , Yang F. , Kushimoto T. , Higashimoto Y. , Yasumoto K. , Valencia J. , Muller J. , Vieira W.D. , Watabe H. , Shabanowitz J. , Hearing V.J. , Hunt D.F. , Appella E.
J. Proteome Res.2:69-79(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
tissue: Melanoma.
16.

"ERp27, a new non-catalytic endoplasmic reticulum-located human protein disulfide isomerase family member, interacts with ERp57."
Alanen H.I. , Williamson R.A. , Howard M.J. , Hatahet F.S. , Salo K.E.H. , Kauppila A. , Kellokumpu S. , Ruddock L.W.
J. Biol. Chem.281:33727-33738(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ERP27
17.

"Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes."
Chi A. , Valencia J.C. , Hu Z.-Z. , Watabe H. , Yamaguchi H. , Mangini N.J. , Huang H. , Canfield V.A. , Cheng K.C. , Yang F. , Abe R. , Yamagishi S. , Shabanowitz J. , Hearing V.J. , Wu C. , Appella E. , Hunt D.F.
J. Proteome Res.5:3135-3144(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]
tissue: Melanoma.
18.

"Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Leukemic T-cell.
19.

"Glucose-regulated protein precursor (GRP78) and tumor rejection antigen (GP96) are unique to hamster caput epididymal spermatozoa."
Kameshwari D.B. , Bhande S. , Sundaram C.S. , Kota V. , Siva A.B. , Shivaji S.
Asian J. Androl.12:344-355(2010) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
20.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
21.

"SERPINA2 is a novel gene with a divergent function from SERPINA1."
Marques P.I. , Ferreira Z. , Martins M. , Figueiredo J. , Silva D.I. , Castro P. , Morales-Hojas R. , Simoes-Correia J. , Seixas S.
PLoS ONE8:E66889-E66889(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SERPINA1 AND SERPINA2;SUBCELLULAR LOCATION
22.

"NMR assignment of the N-terminal domain a of the glycoprotein chaperone ERp57."
Silvennoinen L. , Koivunen P. , Myllyharju J. , Kilpelaeinen I. , Permi P.
J. Biomol. NMR33:136-136(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 25-137
23.

"The solution structure of the second thioredoxin domain of human protein disulfide-isomerase A3."
RIKEN structural genomics initiative (RSGI)
Submitted (2006-10) to the PDB data bank

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 357-485
24.

"Crystal structure of the bb' domains of the protein disulfide isomerase ERp57."
Kozlov G. , Maattanen P. , Schrag J.D. , Pollock S. , Cygler M. , Nagar B. , Thomas D.Y. , Gehring K.
Structure14:1331-1339(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS) OF 134-376;INTERACTION WITH CANX
25.

"Insights into MHC class I peptide loading from the structure of the tapasin-ERp57 thiol oxidoreductase heterodimer."
Dong G. , Wearsch P.A. , Peaper D.R. , Cresswell P. , Reinisch K.M.
Immunity30:21-32(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 25-505 IN COMPLEX WITH TAPBP;SUBUNIT;INTERACTION WITH TAPBP;DISULFIDE BONDS

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