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Index > Protein center > Cbfb(Gene name) > Mouse
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  • Cbfb (Gene name),
  • Core-binding factor subunit beta (Protein name ),  PEBB_MOUSE from NCBI database.
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  • General Annotation
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  • Gene name:
    Cbfb(Pebp2b;Pebpb2);
    Protein name:
    Core-binding factor subunit beta(CBF-beta);
    Alternative:
    SL3-3 enhancer factor 1 subunit beta;Polyomavirus enhancer-binding protein 2 beta subunit(PEA2-beta;PEBP2-beta);SL3/AKV core-binding factor beta subunit;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Heterodimer with RUNX1.
    Function:
    CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL3 and GM-CSF promoters. CBFB enhances DNA binding by RUNX1.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    187
    Sequence:
    50:
    MPRVVPDQRS | KFENEEFFRK | LSRECEIKYT | GFRDRPHEER | QTRFQNACRD | 
    100:
    GRSEIAFVAT | GTNLSLQFFP | ASWQGEQRQT | PSREYVDLER | EAGKVYLKAP | 
    150:
    MILNGVCVIW | KGWIDLHRLD | GMGCLEFDEE | RAQQEDALAQ | QAFEEARRRT | 
    187:
    REFEDRDRSH | REEMEARRQQ | DPSPGSNLGG | GDDLKLR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    UniGene:
    Pfam:
    SMR:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse CBF-beta
    ELISA Kit for Mouse CBF-beta
    CLIA Kit for Mouse CBF-beta
    CLIA Kit for Mouse CBF-beta
    Polyclonal Antibody for Mouse CBF-beta
    Polyclonal Antibody for Mouse CBF-beta
    Monoclonal Antibody for Mouse CBF-beta
    Monoclonal Antibody for Mouse CBF-beta
    Protein for Mouse CBF-beta
    Protein for Mouse CBF-beta

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Molecular cloning and characterization of PEBP2 beta, the heterodimeric partner of a novel Drosophila runt-related DNA binding protein PEBP2 alpha."
      Ogawa E. , Inuzuka M. , Maruyama M. , Satake M. , Naito-Fujimoto M. , Ito Y. , Shigesada K.
      Virology194:314-331(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 3);NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-26;PROTEIN SEQUENCE OF 12-28 AND 95-98
    2. 2.
      "Cloning and characterization of subunits of the T-cell receptor and murine leukemia virus enhancer core-binding factor."
      Wang S. , Wang Q. , Crute B.E. , Melnikova I.N. , Keller S.R. , Speck N.A.
      Mol. Cell. Biol.13:3324-3339(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1; 2 AND 4)
      tissue: Thymus.
    3. 3.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: NOD.
      tissue: Thymus.
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      strain: Czech II.
      tissue: Mammary gland.
    5. 5.
      "The histone- and PRMT5-associated protein COPR5 is required for myogenic differentiation."
      Paul C. , Sardet C. , Fabbrizio E.
      Cell Death Differ.19:900-908(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH COPRS;IDENTIFICATION IN A COMPLEX WITH PRMT5; RUNX1 AND CBFB
    6. 6.
      "Structural analyses of DNA recognition by the AML1/Runx-1 Runt domain and its allosteric control by CBFbeta."
      Tahirov T.H. , Inoue-Bungo T. , Morii H. , Fujikawa A. , Sasaki M. , Kimura K. , Shiina M. , Sato K. , Kumasaka T. , Yamamoto M. , Ishii S. , Ogata K.
      Cell104:755-767(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.65 ANGSTROMS) OF 1-141 IN COMPLEX WITH CEBPB; RUNX1 AND DNA;MUTAGENESIS OF VAL-5; ASN-63 AND ASN-104
    7. 7.
      "Solution structure of core binding factor beta and map of the CBF alpha binding site."
      Huang X. , Peng J.W. , Speck N.A. , Bushweller J.H.
      Nat. Struct. Biol.6:624-627(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-141
    8. 8.
      "Structure and backbone dynamics of Apo-CBFbeta in solution."
      Wolf-Watz M. , Grundstroem T. , Haerd T.
      Biochemistry40:11423-11432(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 1-141
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