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Index > Protein center > PEBP1(Gene name) > Human
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  • PEBP1 (Gene name),
  • Phosphatidylethanolamine-binding protein 1 (Protein name ),  PEBP1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    PEBP1(PBP;PEBP);
    Protein name:
    Phosphatidylethanolamine-binding protein 1(PEBP-1);
    Alternative:
    Neuropolypeptide h3;HCNPpp;Raf kinase inhibitor protein(RKIP);Prostatic-binding protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with Raf-1 and seems to inhibit it.
    Function:
    HCNP may be involved in the function of the presynaptic cholinergic neurons of the central nervous system. HCNP increases the production of choline acetyltransferase but not acetylcholinesterase. Seems to be mediated by a specific receptor.
    Subcellular Location:
    Cytoplasm
    Protein Attributes:
    Sequence length:
    187
    Sequence:
    50:
    MPVDLSKWSG | PLSLQEVDEQ | PQHPLHVTYA | GAAVDELGKV | LTPTQVKNRP | 
    100:
    TSISWDGLDS | GKLYTLVLTD | PDAPSRKDPK | YREWHHFLVV | NMKGNDISSG | 
    150:
    TVLSDYVGSG | PPKGTGLHRY | VWLVYEQDRP | LKCDEPILSN | RSGDHRGKFK | 
    187:
    VASFRKKYEL | RAPVAGTCYQ | AEWDDYVPKL | YEQLSGK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    UniGene:
    SMR:
    MIM:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human PEBP-1
    Cat.:
    E12681h
    Price:
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human PEBP-1
    MSDS:
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    ELISA Kit for Human PEBP-1
    MSDS:
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    ELISA Kit for Human PEBP-1
    Cat.:
    E12681m
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human PEBP-1
    Cat.:
    E12681r
    Price:
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human PEBP-1
    MSDS:
    Please sign in first.
    CLIA Kit for Human PEBP-1
    Cat.:
    U12681m
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human PEBP-1
    Cat.:
    U12681r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human PEBP-1
    MSDS:
    Please sign in first.
    CLIA Kit for Human PEBP-1
    MSDS:
    Please sign in first.
    CLIA Kit for Human PEBP-1
    MSDS:
    Please sign in first.
    CLIA Kit for Human PEBP-1
    Cat.:
    U12681h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
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    Polyclonal Antibody for Human PEBP-1
    Polyclonal Antibody for Human PEBP-1
    Polyclonal Antibody for Human PEBP-1
    Cat.:
    P12681Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human PEBP-1
    Polyclonal Antibody for Human PEBP-1
    Polyclonal Antibody for Human PEBP-1
    Monoclonal Antibody for Human PEBP-1
    Monoclonal Antibody for Human PEBP-1
    Monoclonal Antibody for Human PEBP-1
    Monoclonal Antibody for Human PEBP-1
    Monoclonal Antibody for Human PEBP-1
    Monoclonal Antibody for Human PEBP-1
    Protein for Human PEBP-1
    Protein for Human PEBP-1
    Protein for Human PEBP-1
    Protein for Human PEBP-1
    Protein for Human PEBP-1
    Protein for Human PEBP-1

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    References
    1. 1.
      "A human cDNA sequence homologue of bovine phosphatidylethanolamine-binding protein."
      Hori N. , Keon-Sang C. , Murakawa K. , Matoba R. , Fukushima A. , Okubo K. , Matsubara K.
      Gene140:293-294(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Sequence homology of rat and human HCNP precursor proteins, bovine phosphatidylethanolamine-binding protein and rat 23-kDa protein associated with the opioid-binding protein."
      Tohdoh N. , Tojo S. , Agui H. , Ojika K.
      Brain Res. Mol. Brain Res.30:381-384(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Placenta.
    3. 3.
      Hall L.
      Submitted (1995-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Cerebellum.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
      tissue: Hypothalamus.
      tissue: Lung.
    7. 7.
      "Human liver protein map: a reference database established by microsequencing and gel comparison."
      Hochstrasser D.F. , Frutiger S. , Paquet N. , Bairoch A. , Ravier F. , Pasquali C. , Sanchez J.-C. , Tissot J.-D. , Bjellqvist B. , Vargas R. , Appel R.D. , Hughes G.J.
      Electrophoresis13:992-1001(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 2-11
      tissue: Liver.
    8. 8.
      Lubec G. , Vishwanath V. , Chen W.-Q. , Sun Y.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 8-39; 48-77; 81-113; 120-141 AND 162-187;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Cajal-Retzius cell.
      tissue: Fetal brain cortex.
    9. 9.
      "Amino acid sequence of the Homo sapiens brain 21-23-kDa protein (neuropolypeptide h3), comparison with its counterparts from Rattus norvegicus and Bos taurus species, and expression of its mRNA in different tissues."
      Seddiqi N. , Bollengier F. , Alliel P.M. , Perin J.-P. , Bonnet F. , Bucquoy S. , Jolles P. , Schoentgen F.
      J. Mol. Evol.39:655-660(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 48-187
      tissue: Brain.
    10. 10.
      "Hippocampal cholinergic neurostimulating peptides (HCNP)."
      Ojika K. , Mitake S. , Tohdoh N. , Appel S.H. , Otsuka Y. , Katada E. , Matsukawa N.
      Prog. Neurobiol.60:37-83(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF HCNP
    11. 11.
      "Suppression of Raf-1 kinase activity and MAP kinase signalling by RKIP."
      Yeung K. , Seitz T. , Li S. , Janosch P. , McFerran B. , Kaiser C. , Fee F. , Katsanakis K.D. , Rose D.W. , Mischak H. , Sedivy J.M. , Kolch W.
      Nature401:173-177(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH RAF-1
    12. 12.
      "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks."
      Olsen J.V. , Blagoev B. , Gnad F. , Macek B. , Kumar C. , Mortensen P. , Mann M.
      Cell127:635-648(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    13. 13.
      "The RKIP (Raf-1 Kinase Inhibitor Protein) conserved pocket binds to the phosphorylated N-region of Raf-1 and inhibits the Raf-1-mediated activated phosphorylation of MEK."
      Rath O. , Park S. , Tang H.H. , Banfield M.J. , Brady R.L. , Lee Y.C. , Dignam J.D. , Sedivy J.M. , Kolch W. , Yeung K.C.
      Cell. Signal.20:935-941(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH RAF1
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-42 AND SER-52;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    15. 15.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-52;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    16. 16.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-52;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    17. 17.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    18. 18.
      "15-Lipoxygenase 1 interacts with phosphatidylethanolamine-binding protein to regulate MAPK signaling in human airway epithelial cells."
      Zhao J. , O'Donnell V.B. , Balzar S. , St Croix C.M. , Trudeau J.B. , Wenzel S.E.
      Proc. Natl. Acad. Sci. U.S.A.108:14246-14251(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH ALOX15
    19. 19.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-52;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    20. 20.
      "Function from structure? The crystal structure of human phosphatidylethanolamine-binding protein suggests a role in membrane signal transduction."
      Banfield M.J. , Barker J.J. , Perry A.C. , Brady R.L.
      Structure6:1245-1254(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS)
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