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Index > Protein center > PSENEN(Gene name) > Bovine
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  • PSENEN (Gene name),
  • Gamma-secretase subunit PEN-2 (Protein name ),  PEN2_BOVIN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    PSENEN(PEN2);
    Protein name:
    Gamma-secretase subunit PEN-2;
    Alternative:
    Presenilin enhancer protein 2;
    Organism:
    Bovine (Bos taurus). 
    General Annotation
    Sub Unit:
    Component of the gamma-secretase complex, a complex composed of a presenilin homodimer (PSEN1 or PSEN2), nicastrin (NCSTN), APH1 (APH1A or APH1B) and PSENEN/PEN2. Such minimal complex is sufficient for secretase activity, although other components may exist.
    Function:
    Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
    Subcellular Location:
    Endoplasmic reticulum membrane Multi-pass membrane protein Golgi apparatus cis-Golgi network membrane Multi-pass membrane protein Predominantly located in the endoplasmic reticulum and in the cis-Golgi.
    Protein Attributes:
    Sequence length:
    101
    Sequence:
    50:
    MNLERVSNEE | KLNLCRKYYL | GGFAFLPFLW | LVNIFWFFRE | AFIVPAYTEQ | 
    100:
    SQIKGYVWRS | AVGFFLWVIV | LSTWITIFQI | YRPRWGALGD | YLSFTIPLGT | 
    101:
    P
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Bovine Gamma-secretase subunit PEN-2
    Cat.:
    E3143h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine Gamma-secretase subunit PEN-2
    Cat.:
    E3143m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Bovine Gamma-secretase subunit PEN-2
    Cat.:
    E3143r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Bovine Gamma-secretase subunit PEN-2
    Cat.:
    E3143b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Gamma-secretase subunit PEN-2
    Cat.:
    U3143r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Gamma-secretase subunit PEN-2
    Cat.:
    U3143b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Gamma-secretase subunit PEN-2
    Cat.:
    U3143h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Bovine Gamma-secretase subunit PEN-2
    Cat.:
    U3143m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Bovine Gamma-secretase subunit PEN-2
    Polyclonal Antibody for Bovine Gamma-secretase subunit PEN-2
    Cat.:
    P3143Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Gamma-secretase subunit PEN-2
    Cat.:
    P3143Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Bovine Gamma-secretase subunit PEN-2
    Monoclonal Antibody for Bovine Gamma-secretase subunit PEN-2
    Monoclonal Antibody for Bovine Gamma-secretase subunit PEN-2
    Monoclonal Antibody for Bovine Gamma-secretase subunit PEN-2
    Monoclonal Antibody for Bovine Gamma-secretase subunit PEN-2
    Protein for Bovine Gamma-secretase subunit PEN-2
    Cat.:
    R3143h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Bovine Gamma-secretase subunit PEN-2
    Protein for Bovine Gamma-secretase subunit PEN-2
    Protein for Bovine Gamma-secretase subunit PEN-2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Bovine presenilin enhancer 2."
      Jeong Y.-H. , Lee S.-M. , Park H.-Y. , Yoon D.-H. , Chung E.-R. , Kang M.-J.
      Submitted (2004-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Estimating probability of parentage in U.S. beef and dairy cattle with single nucleotide polymorphisms."
      Heaton M.P. , Clawson M.L. , Snelling W.M. , Keele J.W. , Harhay G.P. , Wiedmann R.T. , Bennett G.L. , Smith T.P.L. , Stone R.T. , Freking B.A. , Van Tassell C.P. , Sonstegard T.S. , Gasbarre L.C. , Carr J. , DiBello P. , Kumar M. , Lee M.S. , Murthy J. , more...
      Submitted (2004-12) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
    3. 3.
      NIH - Mammalian Gene Collection (MGC) project
      Submitted (2005-08) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: Crossbred X Angus.
      tissue: Ileum.
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