EPX ELISA Kit for Human(Homo sapiens) | EIAab.comEPX ELISA Kit for Human(Homo sapiens)

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EPX (Gene name),

Eosinophil peroxidase (Protein name ), PERE_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

EPX(EPER;EPO;EPP);

Protein name:

Eosinophil peroxidase(EPO);

Alternative:

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Tetramer of two light chains and two heavy chains.

Function:

Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils. Shows significant inhibitory activity towards Mycobacterium tuberculosis H37Rv by inducing bacterial fragmentation and lysis.

Subcellular Location:

Cytoplasmic granule Cytoplasmic granules of eosinophils.

Protein Attributes:

Sequence length:

715

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

650:

700:

715:

CSRIPRLNLS | AWRGT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

hsa:8288

MIM:

131399

STRING:

9606.ENSP00000225371

UniGene:

Hs.279259

String:

P11678

SMR:

P11678

Pfam:

PF03098

Uniprot:

P11678

FOR

ELISA Kit for Human EPO

Cat.:

E8699h

Price:

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human EPO

MSDS:

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ELISA Kit for Human EPO

Cat.:

E8699m

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

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CLIA Kit for Human EPO

MSDS:

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CLIA Kit for Human EPO

Cat.:

U8699h

Price:

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Manual:

Looking for manual.

MSDS:

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Packing:

96T

Range:

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CLIA Kit for Human EPO

Cat.:

U8699m

Price:

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human EPO

Cat.:

P8699Rb-m

Price:

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human EPO

Cat.:

P8699Rb-h

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human EPO

Protein for Human EPO

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

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References

1.

"Molecular cloning and characterization of a chromosomal gene for human eosinophil peroxidase."
Sakamaki K. , Tomonaga M. , Tsukui K. , Nagata S.
J. Biol. Chem.264:16828-16836(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
tissue: Placenta.
2.

NIEHS SNPs program
Submitted (2005-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA];VARIANTS MET-40; HIS-122; GLU-249; ARG-276; LEU-292; PRO-326; LEU-358; HIS-364; THR-441; GLN-496 AND TYR-572
3.

"Molecular cloning of the human eosinophil peroxidase. Evidence for the existence of a peroxidase multigene family."
Ten R.M. , Pease L.R. , McKean D.J. , Bell M.P. , Gleich G.J.
J. Exp. Med.169:1757-1769(1989) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 13-715;PROTEIN SEQUENCE OF 140-187 AND 251-288
tissue: Blood.
4.

"Biochemical evidence for heme linkage through esters with Asp-93 and Glu-241 in human eosinophil peroxidase. The ester with Asp-93 is only partially formed in vivo."
Oxvig C. , Thomsen A.R. , Overgaard M.T. , Sorensen E.S. , Hoejrup P. , Bjerrum M.J. , Gleich G.J. , Sottrup-Jensen L.
J. Biol. Chem.274:16953-16958(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COVALENT HEME ATTACHMENT;PARTIAL PROTEIN SEQUENCE
tissue: Blood.
5.

"Human eosinophil peroxidase induces surface alteration, killing, and lysis of Mycobacterium tuberculosis."
Borelli V. , Vita F. , Shankar S. , Soranzo M.R. , Banfi E. , Scialino G. , Brochetta C. , Zabucchi G.
Infect. Immun.71:605-613(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
6.

"Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase."
Ulrich M. , Petre A. , Youhnovski N. , Proemm F. , Schirle M. , Schumm M. , Pero R.S. , Doyle A. , Checkel J. , Kita H. , Thiyagarajan N. , Acharya K.R. , Schmid-Grendelmeier P. , Simon H.-U. , Schwarz H. , Tsutsui M. , Shimokawa H. , Bellon G. , more...
J. Biol. Chem.283:28629-28640(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;NITRATION AT TYR-488
7.

"Hereditary eosinophil peroxidase deficiency: immunochemical and spectroscopic studies and evidence for a compound heterozygosity of the defect."
Romano M. , Patriarca P. , Melo C. , Baralle F.E. , Dri P.
Proc. Natl. Acad. Sci. U.S.A.91:12496-12500(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT EPXD HIS-286
8.

"High contribution contrast between the genes of eosinophil peroxidase and IL-4 receptor alpha-chain in Japanese cedar pollinosis."
Nakamura H. , Miyagawa K. , Ogino K. , Endo T. , Imai T. , Ozasa K. , Motohashi Y. , Matsuzaki I. , Sasahara S. , Hatta K. , Eboshida A.
J. Allergy Clin. Immunol.112:1127-1131(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS HIS-326; LEU-326 AND LEU-358;POLYMORPHISM

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