Gene name:
Ptgs2 (Cox-2;Cox2;Pghs-b;Tis10) ;
Protein name:
Prostaglandin G/H synthase 2 ;
Alternative:
Glucocorticoid-regulated inflammatory cyclooxygenase ;Cyclooxygenase-2 (COX-2) ;Macrophage activation-associated marker protein P71/73 ;Gripghs ;PHS II ;PES-2 ;Prostaglandin-endoperoxide synthase 2 ;Prostaglandin H2 synthase 2 (PGH synthase 2;PGHS-2) ;TIS10 protein ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Mediates the formation of prostaglandins from arachidonate. May have a role as a major mediator of inflammation and/or a role for prostanoid signaling in activity-dependent plasticity.
Subcellular Location:
Microsome membrane
Peripheral membrane protein
Endoplasmic reticulum membrane
Peripheral membrane protein
Protein Attributes:
50:
MLFRAVLLCA | ALGLSQAANP | CCSNPCQNRG | ECMSTGFDQY | KCDCTRTGFY |
100:
GENCTTPEFL | TRIKLLLKPT | PNTVHYILTH | FKGVWNIVNN | IPFLRSLIMK |
150:
YVLTSRSYLI | DSPPTYNVHY | GYKSWEAFSN | LSYYTRALPP | VADDCPTPMG |
200:
VKGNKELPDS | KEVLEKVLLR | REFIPDPQGS | NMMFAFFAQH | FTHQFFKTDH |
250:
KRGPGFTRGL | GHGVDLNHIY | GETLDRQHKL | RLFKDGKLKY | QVIGGEVYPP |
300:
TVKDTQVEMI | YPPHIPENLQ | FAVGQEVFGL | VPGLMMYATI | WLREHNRVCD |
350:
ILKQEHPEWG | DEQLFQTSRL | ILIGETIKIV | IEDYVQHLSG | YHFKLKFDPE |
400:
LLFNQQFQYQ | NRIASEFNTL | YHWHPLLPDT | FNIEDQEYSF | KQFLYNNSIL |
450:
LEHGLTQFVE | SFTRQIAGRV | AGGRNVPIAV | QAVAKASIDQ | SREMKYQSLN |
500:
EYRKRFSLKP | YTSFEELTGE | KEMAAELKAL | YSDIDVMELY | PALLVEKPRP |
550:
DAIFGETMVE | LGAPFSLKGL | MGNPICSPQY | WKPSTFGGEV | GFKIINTASI |
600:
QSLICNNVKG | CPFTSFNVQD | PQPTKTATIN | ASASHSRLDD | INPTVLIKRR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Rat
Chicken
Bovine
Mouse
Rabbit
ELISA Kit for Mouse Prostaglandin G/H synthase 2
ELISA Kit for Mouse Prostaglandin G/H synthase 2
ELISA Kit for Mouse Prostaglandin G/H synthase 2
ELISA Kit for Mouse Prostaglandin G/H synthase 2
ELISA Kit for Mouse Prostaglandin G/H synthase 2
ELISA Kit for Mouse Prostaglandin G/H synthase 2
CLIA Kit for Mouse Prostaglandin G/H synthase 2
CLIA Kit for Mouse Prostaglandin G/H synthase 2
CLIA Kit for Mouse Prostaglandin G/H synthase 2
CLIA Kit for Mouse Prostaglandin G/H synthase 2
CLIA Kit for Mouse Prostaglandin G/H synthase 2
CLIA Kit for Mouse Prostaglandin G/H synthase 2
Polyclonal Antibody for Mouse Prostaglandin G/H synthase 2
Polyclonal Antibody for Mouse Prostaglandin G/H synthase 2
Polyclonal Antibody for Mouse Prostaglandin G/H synthase 2
Polyclonal Antibody for Mouse Prostaglandin G/H synthase 2
Polyclonal Antibody for Mouse Prostaglandin G/H synthase 2
Polyclonal Antibody for Mouse Prostaglandin G/H synthase 2
Monoclonal Antibody for Mouse Prostaglandin G/H synthase 2
Monoclonal Antibody for Mouse Prostaglandin G/H synthase 2
Monoclonal Antibody for Mouse Prostaglandin G/H synthase 2
Monoclonal Antibody for Mouse Prostaglandin G/H synthase 2
Monoclonal Antibody for Mouse Prostaglandin G/H synthase 2
Monoclonal Antibody for Mouse Prostaglandin G/H synthase 2
Protein for Mouse Prostaglandin G/H synthase 2
Protein for Mouse Prostaglandin G/H synthase 2
Protein for Mouse Prostaglandin G/H synthase 2
Protein for Mouse Prostaglandin G/H synthase 2
Protein for Mouse Prostaglandin G/H synthase 2
Protein for Mouse Prostaglandin G/H synthase 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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Citations
[1].
J Xiao, E C Liong, M T Ling et al.
References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Swiss .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
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Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
strain :
NOD .
tissue :
Hippocampus .
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Mammary gland .
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Spleen .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : GLYCOSYLATION AT ASN-53; ASN-130; ASN-396 AND ASN-580;ABSENCE OF GLYCOSYLATION AT ASN-592
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Cited for : ERRATUM
15.
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[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS) OF 18-569 IN COMPLEX WITH ARACHIDONIC ACID;GLYCOSYLATION AT ASN-53; ASN-130 AND ASN-396
16.
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Cited for : X-RAY CRYSTALLOGRAPHY (2.90 ANGSTROMS) IN COMPLEX WITH HEME AND DICLOFENAC;CATALYTIC ACTIVITY;FUNCTION;COFACTOR;DISULFIDE BONDS;ENZYME REGULATION;GLYCOSYLATION AT ASN-53; ASN-130 AND ASN-396
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Cited for : X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) OF 20-604 IN COMPLEX WITH HEME; ACRYLIC ACID; ARACHIDONIC ACID AND DOCOSAHEXAENOIC ACID;CATALYTIC ACTIVITY;ACTIVE SITE;SUBUNIT;COFACTOR;FUNCTION;DISULFIDE BONDS;MUTAGENESIS OF LEU-517 AND ASN-580;GLYCOSYLATION AT ASN-53; ASN-130; ASN-396 AND ASN-580
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Cited for : X-RAY CRYSTALLOGRAPHY (1.73 ANGSTROMS) OF 18-604 IN COMPLEXES WITH HEME AND NAPROXEN ANALOGS;FUNCTION;CATALYTIC ACTIVITY;ENZYME REGULATION;DISULFIDE BONDS;GLYCOSYLATION AT ASN-53; ASN-130 AND ASN-396
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Cited for : X-RAY CRYSTALLOGRAPHY (2.20 ANGSTROMS) OF 20-599 IN COMPLEX WITH HEME; ACRYLIC ACID AND ARACHIDONIC ACID;FUNCTION;CATALYTIC ACTIVITY;GLYCOSYLATION AT ASN-53; ASN-130 AND ASN-396