Pias3 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comPias3 ELISA Kit for Rat(Rattus norvegicus)

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Pias3 (Gene name),

E3 SUMO-protein ligase PIAS3 (Protein name ), PIAS3_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Pias3;

Protein name:

E3 SUMO-protein ligase PIAS3;

Alternative:

Potassium channel-associated protein;KChAP;Protein inhibitor of activated STAT protein 3;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Binds SUMO1 and UBE2I. Interacts with AR, BCL11A, GFI1, HMGA2, IRF1, MITF, NCOA2, as well as with STAT3, after treatment with IL6, CNTF or OSM and with STAT5, after PRL stimulation. Interacts with PLAG1 (By similarity). Interacts with ZFHX3.

Function:

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. The effects of this transcriptional coregulation, transactivation or silencing, may vary depending upon the biological context.

Subcellular Location:

Nucleus speckle

Protein Attributes:

Sequence length:

628

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

600:

628:

SSLREGHGGP | LPSGPSLTGC | RSDVISLD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

UniGene:

Rn.14548

Pfam:

PF14324

SMR:

O70260

Pfam:

PF02891

STRING:

10116.ENSRNOP00000028814

String:

O70260

KEGG:

rno:83614

Uniprot:

O70260

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ELISA Kit for Rat E3 SUMO-protein ligase PIAS3

Cat.:

E1591m

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96T

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ELISA Kit for Rat E3 SUMO-protein ligase PIAS3

Cat.:

E1591h

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96T

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ELISA Kit for Rat E3 SUMO-protein ligase PIAS3

Cat.:

E1591r

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96T

CLIA Kit for Rat E3 SUMO-protein ligase PIAS3

Cat.:

U1591r

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Packing:

96T

CLIA Kit for Rat E3 SUMO-protein ligase PIAS3

Cat.:

U1591m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Rat E3 SUMO-protein ligase PIAS3

Cat.:

U1591h

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MSDS:

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Packing:

96T

Polyclonal Antibody for Rat E3 SUMO-protein ligase PIAS3

Cat.:

P1591Rb-r

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40ug/0.2ml

Polyclonal Antibody for Rat E3 SUMO-protein ligase PIAS3

Cat.:

P1591Rb-h

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40ug/0.2ml

Polyclonal Antibody for Rat E3 SUMO-protein ligase PIAS3

Cat.:

P1591Rb-m

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Packing:

40ug/0.2ml

Monoclonal Antibody for Rat E3 SUMO-protein ligase PIAS3

Protein for Rat E3 SUMO-protein ligase PIAS3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and expression of a novel K+ channel regulatory protein, KChAP."
Wible B.A. , Yang Q. , Kuryshev Y.A. , Accili E.A. , Brown A.M.
J. Biol. Chem.273:11745-11751(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];SUBCELLULAR LOCATION;TISSUE SPECIFICITY
tissue: Brain.
2.

"A new role for the STAT3 inhibitor, PIAS3: a repressor of microphthalmia transcription factor."
Levy C. , Nechushtan H. , Razin E.
J. Biol. Chem.277:1962-1966(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MITF
3.

"The intranuclear prolactin/cyclophilin B complex as a transcriptional inducer."
Rycyzyn M.A. , Clevenger C.V.
Proc. Natl. Acad. Sci. U.S.A.99:6790-6795(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH STAT5

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