Gene name:
PLCB1 (KIAA0581) ;
Protein name:
1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1 ;
Alternative:
Phosphoinositide phospholipase C-beta-1 ;PLC-154 ;Phospholipase C-beta-1 (PLC-beta-1) ;Phospholipase C-I (PLC-I) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with DGKQ.
Function:
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Subcellular Location:
N/A
Protein Attributes:
50:
MAGAQPGVHA | LQLKPVCVSD | SLKKGTKFVK | WDDDSTIVTP | IILRTDPQGF |
100:
FFYWTDQNKE | TELLDLSLVK | DARCGRHAKA | PKDPKLRELL | DVGNIGRLEQ |
150:
RMITVVYGPD | LVNISHLNLV | AFQEEVAKEW | TNEVFSLATN | LLAQNMSRDA |
200:
FLEKAYTKLK | LQVTPEGRIP | LKNIYRLFSA | DRKRVETALE | ACSLPSSRND |
250:
SIPQEDFTPE | VYRVFLNNLC | PRPEIDNIFS | EFGAKSKPYL | TVDQMMDFIN |
300:
LKQRDPRLNE | ILYPPLKQEQ | VQVLIEKYEP | NNSLARKGQI | SVDGFMRYLS |
350:
GEENGVVSPE | KLDLNEDMSQ | PLSHYFINSS | HNTYLTAGQL | AGNSSVEMYR |
400:
QVLLSGCRCV | ELDCWKGRTA | EEEPVITHGF | TMTTEISFKE | VIEAIAECAF |
450:
KTSPFPILLS | FENHVDSPKQ | QAKMAEYCRL | IFGDALLMEP | LEKYPLESGV |
500:
PLPSPMDLMY | KILVKNKKKS | HKSSEGSGKK | KLSEQASNTY | SDSSSMFEPS |
550:
SPGAGEADTE | SDDDDDDDDC | KKSSMDEGTA | GSEAMATEEM | SNLVNYIQPV |
600:
KFESFEISKK | RNKSFEMSSF | VETKGLEQLT | KSPVEFVEYN | KMQLSRIYPK |
650:
GTRVDSSNYM | PQLFWNAGCQ | MVALNFQTMD | LAMQINMGMY | EYNGKSGYRL |
700:
KPEFMRRPDK | HFDPFTEGIV | DGIVANTLSV | KIISGQFLSD | KKVGTYVEVD |
750:
MFGLPVDTRR | KAFKTKTSQG | NAVNPVWEEE | PIVFKKVVLP | TLACLRIAVY |
800:
EEGGKFIGHR | ILPVQAIRPG | YHYICLRNER | NQPLTLPAVF | VYIEVKDYVP |
850:
DTYADVIEAL | SNPIRYVNLM | EQRAKQLAAL | TLEDEEEVKK | EADPGETPSE |
900:
APSEARTTPA | ENGVNHTTTL | TPKPPSQALH | SQPAPGSVKA | PAKTEDLIQS |
950:
VLTEVEAQTI | EELKQQKSFV | KLQKKHYKEM | KDLVKRHHKK | TTDLIKEHTT |
1000:
KYNEIQNDYL | RRRAALEKSA | KKDSKKKSEP | SSPDHGSSTI | EQDLAALDAE |
1050:
MTQKLIDLKD | KQQQQLLNLR | QEQYYSEKYQ | KREHIKLLIQ | KLTDVAEECQ |
1100:
NNQLKKLKEI | CEKEKKELKK | KMDKKRQEKI | TEAKSKDKSQ | MEEEKTEMIR |
1150:
SYIQEVVQYI | KRLEEAQSKR | QEKLVEKHKE | IRQQILDEKP | KLQVELEQEY |
1200:
QDKFKRLPLE | ILEFVQEAMK | GKISEDSNHG | SAPLSLSSDP | GKVNHKTPSS |
1216:
EELGGDIPGK | EFDTPL
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Rat
Human
Mouse
ELISA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
ELISA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
ELISA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
ELISA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
CLIA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
CLIA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
CLIA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
CLIA Kit for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
Polyclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
Polyclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
Polyclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
Polyclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
Monoclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
Monoclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
Monoclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
Monoclonal Antibody for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
Protein for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
Protein for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
Protein for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
Protein for Human 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS A AND B)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION
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Submitted (2005-09) to the EMBL/GenBank/DDBJ databases
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS A AND B)
tissue :
Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 261-1216 (ISOFORM B)
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Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 417-1062 (ISOFORMS A AND B)
tissue :
Placenta .
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Cited for : INTERACTION WITH DGKQ
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Europe PMC ]
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Abstract ]
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Cited for : INVOLVEMENT IN EIEE12
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PubMed ]
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Europe PMC ]
[
Abstract ]
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Cited for : VARIANT [LARGE SCALE ANALYSIS] PRO-907