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Index > Protein center > POSTN(Gene name) > Human
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  • POSTN (Gene name),
  • Periostin (Protein name ),  POSTN_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    POSTN(OSF2);
    Protein name:
    Periostin(PN);
    Alternative:
    Osteoblast-specific factor 2(OSF-2);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.
    Subcellular Location:
    Secreted extracellular space extracellular matrix
    Protein Attributes:
    Sequence length:
    836
    Sequence:
    50:
    MIPFLPMFSL | LLLLIVNPIN | ANNHYDKILA | HSRIRGRDQG | PNVCALQQIL | 
    100:
    GTKKKYFSTC | KNWYKKSICG | QKTTVLYECC | PGYMRMEGMK | GCPAVLPIDH | 
    150:
    VYGTLGIVGA | TTTQRYSDAS | KLREEIEGKG | SFTYFAPSNE | AWDNLDSDIR | 
    200:
    RGLESNVNVE | LLNALHSHMI | NKRMLTKDLK | NGMIIPSMYN | NLGLFINHYP | 
    250:
    NGVVTVNCAR | IIHGNQIATN | GVVHVIDRVL | TQIGTSIQDF | IEAEDDLSSF | 
    300:
    RAAAITSDIL | EALGRDGHFT | LFAPTNEAFE | KLPRGVLERI | MGDKVASEAL | 
    350:
    MKYHILNTLQ | CSESIMGGAV | FETLEGNTIE | IGCDGDSITV | NGIKMVNKKD | 
    400:
    IVTNNGVIHL | IDQVLIPDSA | KQVIELAGKQ | QTTFTDLVAQ | LGLASALRPD | 
    450:
    GEYTLLAPVN | NAFSDDTLSM | DQRLLKLILQ | NHILKVKVGL | NELYNGQILE | 
    500:
    TIGGKQLRVF | VYRTAVCIEN | SCMEKGSKQG | RNGAIHIFRE | IIKPAEKSLH | 
    550:
    EKLKQDKRFS | TFLSLLEAAD | LKELLTQPGD | WTLFVPTNDA | FKGMTSEEKE | 
    600:
    ILIRDKNALQ | NIILYHLTPG | VFIGKGFEPG | VTNILKTTQG | SKIFLKEVND | 
    650:
    TLLVNELKSK | ESDIMTTNGV | IHVVDKLLYP | ADTPVGNDQL | LEILNKLIKY | 
    700:
    IQIKFVRGST | FKEIPVTVYT | TKIITKVVEP | KIKVIEGSLQ | PIIKTEGPTL | 
    750:
    TKVKIEGEPE | FRLIKEGETI | TEVIHGEPII | KKYTKIIDGV | PVEITEKETR | 
    800:
    EERIITGPEI | KYTRISTGGG | ETEETLKKLL | QEEVTKVTKF | IEGGDGHLFE | 
    836:
    DEEIKRLLQG | DTPVRKLQAN | KKVQGSRRRL | REGRSQ
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    MIM:
    SMR:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human PN
    Cat.:
    E1767m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human PN
    Cat.:
    E1767h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human PN
    Cat.:
    U1767h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human PN
    Cat.:
    U1767m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    Polyclonal Antibody for Human PN
    Cat.:
    P1767Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human PN
    Cat.:
    P1767Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human PN
    Monoclonal Antibody for Human PN
    Protein for Human PN
    Cat.:
    R1767h
    Price:
    Please sign in first.
    Packing:
    1mg
    Purity:
    >90%
    Protein for Human PN

    R&D Technical Data
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    12% SDS-PAGE analysis

              12% SDS-PAGE analysis

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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "Osteoblast-specific factor 2: cloning of a putative bone adhesion protein with homology with the insect protein fasciclin I."
      Takeshita S. , Kikuno R. , Tezuka K. , Amann E.
      Biochem. J.294:271-278(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2)
      tissue: Osteosarcoma.
      tissue: Placenta.
    2. 2.
      "Periostin secreted by epithelial ovarian carcinoma is a ligand for alpha(V)beta(3) and alpha(V)beta(5) integrins and promotes cell motility."
      Gillan L. , Matei D. , Fishman D.A. , Gerbin C.S. , Karlan B.Y. , Chang D.D.
      Cancer Res.62:5358-5364(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3);FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    3. 3.
      "Novel isoforms of periostin expressed in the human thyroid."
      Bai Y. , Nakamura M. , Zhou G. , Li Y. , Liu Z. , Ozaki T. , Mori I. , Kakudo K.
      Jpn. Clin. Med.1:13-20(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5; 6; 7);ALTERNATIVE SPLICING;TISSUE SPECIFICITY
    4. 4.
      "Identification and characterization of a novel periodontal ligament-specific periostin isoform."
      Yamada S. , Maeda K. , Matsubara K. , Murakami S.
      Submitted (2005-02) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 4)
      tissue: Periodontal ligament.
    5. 5.
      "The DNA sequence and analysis of human chromosome 13."
      Dunham A. , Matthews L.H. , Burton J. , Ashurst J.L. , Howe K.L. , Ashcroft K.J. , Beare D.M. , Burford D.C. , Hunt S.E. , Griffiths-Jones S. , Jones M.C. , Keenan S.J. , Oliver K. , Scott C.E. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews D.T. , more...
      Nature428:522-528(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
    8. 8.
      "OSF-2 expression in head and neck squamous cell carcinomas."
      Habtemichael N. , Schweitzer A. , Knauer S. , Stauber R.H.
      Submitted (2009-11) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-798 (ISOFORM 5)
    9. 9.
      "Serum level of the periostin, a homologue of an insect cell adhesion molecule, as a prognostic marker in nonsmall cell lung carcinomas."
      Sasaki H. , Dai M. , Auclair D. , Fukai I. , Kiriyama M. , Yamakawa Y. , Fujii Y. , Chen L.B.
      Cancer92:843-848(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    10. 10.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ERRATUM
    11. 11.
      "Acquired expression of periostin by human breast cancers promotes tumor angiogenesis through up-regulation of vascular endothelial growth factor receptor 2 expression."
      Shao R. , Bao S. , Bai X. , Blanchette C. , Anderson R.M. , Dang T. , Gishizky M.L. , Marks J.R. , Wang X.-F.
      Mol. Cell. Biol.24:3992-4003(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    12. 12.
      "Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry."
      Liu T. , Qian W.-J. , Gritsenko M.A. , Camp D.G. II , Monroe M.E. , Moore R.J. , Smith R.D.
      J. Proteome Res.4:2070-2080(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-599
      tissue: Plasma.
    13. 13.
      "Periostin, a member of a novel family of vitamin K-dependent proteins, is expressed by mesenchymal stromal cells."
      Coutu D.L. , Wu J.H. , Monette A. , Rivard G.-E. , Blostein M.D. , Galipeau J.
      J. Biol. Chem.283:17991-18001(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;GAMMA-CARBOXYGLUTAMATION
    14. 14.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-599
      tissue: Liver.
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