Gene name:
Ppp1r10 (Cat53;Pnuts) ;
Protein name:
Serine/threonine-protein phosphatase 1 regulatory subunit 10 ;
Alternative:
MHC class I region proline-rich protein CAT53 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Component of the PTW/PP1 phosphatase complex, composed of PPP1R10/PNUTS, TOX4, WDR82, and PPP1CA or PPP1CB or PPP1CC. Interacts with PPP1CC (By similarity). Interacts with PPP1CA, WDR82 and TOX4.
Function:
Scaffold protein which mediates the formation of the PTW/PP1 phosphatase complex by providing a binding platform to each component of the complex. The PTW/PP1 phosphatase complex plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. Mediates interaction of WDR82 and PPP1CA. Inhibitor of PPP1CA and PPP1CC phosphatase activities. Has inhibitory activity on PPP1CA only when phosphorylated. Binds to mRNA, single-stranded DNA (ssDNA), poly(A) and poly(G) homopolymers.
Subcellular Location:
Nucleus
Found in discrete nucleoplasmic bodies and within nucleoli (By similarity). Associates with chromatin during interphase, excluded from condensed chromosomes during early mitosis and is reloaded onto chromosomes at the late telophase.
Protein Attributes:
50:
MGSGPIDPKE | LLKGLDSFLT | RDGEVKSVDG | ISKIFSLMKE | ARKMVSRCTY |
100:
LNIILQTRAP | EVLVKFIDVG | GYKLLNNWLT | YSKTTNNIPL | LQQILLTLQH |
150:
LPLTVDHLKQ | NNTAKLVKQL | SKSSEDEELR | KLASVLVSDW | MAVIRSQSST |
200:
QPAEKDKKKR | KEEGKSRTTL | PERPLTEVKA | ETRAEEAPEK | KKEKPKSLRT |
250:
TAPSHAKFRS | TGLELDTPSL | VPVKKNSSTV | VVSDKYNLKP | IPLKRQSATA |
300:
APGDAAPPAE | KKYKPLNTAP | NTTKEIKVKI | IPPQPMEGLG | FLDALNSAPV |
350:
PGIKIKKKKK | VLSPTAAKPS | PFEGKTSTEQ | STAKPSSPEP | APPAEPMDTD |
400:
RPGTPVPPVE | VPELMDAASS | EPGALDAKPV | DSPGDPNQLT | RKGRKRKTVT |
450:
WPEEGKLREY | FYFELDETER | VNVNKIKDFG | EAAKREILSD | RHAFETARRL |
500:
SHDNMEEKVP | WVCPRPLVLP | SPLVIPGSNS | QERYIQAERE | KGILQELFLN |
550:
KESPHEPDPE | PYEPIPPKLI | PLDEECAMDE | TPYVETLEPG | GSGGSPDGAG |
600:
GSKLPPVLAN | LMGSMGAGKS | PQGPGGGGIN | VQEILTSIMG | SPNSHPSEEL |
650:
LKQPDYSDKL | KQMLVPHGLL | GPGPVANGFP | PGGPGGPKGM | QHFPPGPGGP |
700:
MPGPHGGPGG | PVGPRLLGPP | PPSRGGDPFW | DGPGDPMRGG | PMRGGPGPAP |
750:
GPYHRGRGGR | GGNEPPPPPP | FRGARGGRSG | GGPPNGRGGP | GGGGMVGGGG |
800:
HRPHEGPGGS | MGSGHRSHDG | PGGNMGSGHR | SHDGPGGNMG | GSGGHRSHEG |
850:
PGHGGPHGHR | PHDVPSHRGH | DHRGPPPHEH | RGHDGHGGGG | HRGHDGGHSH |
888:
GGDMSNRPVC | RHFMMKGNCR | YENNCAFYHP | GVNGPPLP
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Pig
Mouse
Human
Rat
ELISA Kit for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
ELISA Kit for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
ELISA Kit for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
ELISA Kit for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
CLIA Kit for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
CLIA Kit for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
CLIA Kit for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
CLIA Kit for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
Polyclonal Antibody for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
Polyclonal Antibody for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
Polyclonal Antibody for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
Polyclonal Antibody for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
Monoclonal Antibody for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
Monoclonal Antibody for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
Monoclonal Antibody for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
Monoclonal Antibody for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
Protein for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
Protein for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
Protein for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
Protein for Mouse Serine/threonine-protein phosphatase 1 regulatory subunit 10
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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C57BL/6J .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-273
strain :
C57BL/6J .
tissue :
Lung .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : IDENTIFICATION IN THE PTW/PP1 PHOSPHATASE COMPLEX;FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH PPP1CA; TOX4 AND WDR82;MUTAGENESIS OF TRP-401