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Index > Protein center > PPP2CA(Gene name) > Chicken
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  • PPP2CA (Gene name),
  • Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (Protein name ),  PP2AA_CHICK from NCBI database.
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  • Gene name:
    PPP2CA;
    Protein name:
    Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform(PP2A-alpha);
    Alternative:

    Organism:
    Chicken (Gallus gallus). 
    General Annotation
    Sub Unit:
    PP2A consists of a common heterodimeric core enzyme, composed of PPP2CA a 36 kDa catalytic subunit (subunit C) and PPP2R1A a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. May indirectly interact with SGOL1, most probably through regulatory B56 subunits.
    Function:
    PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
    Subcellular Location:
    Cytoplasm Nucleus Chromosome centromere Cytoplasm cytoskeleton spindle pole In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.
    Protein Attributes:
    Sequence length:
    309
    Sequence:
    50:
    MEEKSFAKEL | DQWIEQLNEC | RQLSESQVRS | LCEKAKEILT | KESNVQEVRC | 
    100:
    PVTVCGDVHG | QFHDLMELFR | IGGKSPDTNY | LFMGDYVDRG | YYSVETVTLL | 
    150:
    VALKVRYPER | ITILRGNHES | RQITQVYGFY | DECLRKYGNA | NVWKYFTDLF | 
    200:
    DYLPLTALVD | GQIFCLHGGL | SPSIDTLDHI | RALDRLQEVP | HEGPMCDLLW | 
    250:
    SDPDDRGGWG | ISPRGAGYTF | GQDISETFNH | ANGLTLVSRA | HQLVMEGYNW | 
    300:
    CHDRNVVTIF | SAPNYCYRCG | NQAAIMELDD | TLKYSFLQFD | PAPRRGEPHV | 
    309:
    TRRTPDYFL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Chicken PP2A-alpha
    ELISA Kit for Chicken PP2A-alpha
    ELISA Kit for Chicken PP2A-alpha
    ELISA Kit for Chicken PP2A-alpha
    ELISA Kit for Chicken PP2A-alpha
    ELISA Kit for Chicken PP2A-alpha
    ELISA Kit for Chicken PP2A-alpha
    CLIA Kit for Chicken PP2A-alpha
    CLIA Kit for Chicken PP2A-alpha
    CLIA Kit for Chicken PP2A-alpha
    CLIA Kit for Chicken PP2A-alpha
    CLIA Kit for Chicken PP2A-alpha
    CLIA Kit for Chicken PP2A-alpha
    CLIA Kit for Chicken PP2A-alpha
    Polyclonal Antibody for Chicken PP2A-alpha
    Polyclonal Antibody for Chicken PP2A-alpha
    Polyclonal Antibody for Chicken PP2A-alpha
    Polyclonal Antibody for Chicken PP2A-alpha
    Polyclonal Antibody for Chicken PP2A-alpha
    Polyclonal Antibody for Chicken PP2A-alpha
    Polyclonal Antibody for Chicken PP2A-alpha
    Monoclonal Antibody for Chicken PP2A-alpha
    Monoclonal Antibody for Chicken PP2A-alpha
    Monoclonal Antibody for Chicken PP2A-alpha
    Monoclonal Antibody for Chicken PP2A-alpha
    Monoclonal Antibody for Chicken PP2A-alpha
    Monoclonal Antibody for Chicken PP2A-alpha
    Monoclonal Antibody for Chicken PP2A-alpha
    Protein for Chicken PP2A-alpha
    Protein for Chicken PP2A-alpha
    Protein for Chicken PP2A-alpha
    Protein for Chicken PP2A-alpha
    Protein for Chicken PP2A-alpha
    Protein for Chicken PP2A-alpha
    Protein for Chicken PP2A-alpha

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    References
    1. 1.
      "Molecular cloning of cDNA encoding the catalytic subunit of chicken gizzard type 2A protein phosphatase."
      Ito M. , Inoue M. , Shimizu H. , Konishi T. , Kuno T. , Tanaka C. , Hartshorne D. , Nakano T.
      Submitted (1994-07) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Gizzard.
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