Protein name:
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (PP2A-beta) ;
Alternative:
Organism:
Rabbit (Oryctolagus cuniculus).
General Annotation
Sub Unit:
PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Binds PPME1 (By similarity). May indirectly interact with SGOL1, most probably through regulatory B56 subunits. Found in a complex with at least ARL2, PPP2CB, PPP2R1A, PPP2R2A, PPP2R5E and TBCD. Interacts with TBCD.
Function:
PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
Subcellular Location:
Cytoplasm
Nucleus
Chromosome
centromere
Cytoplasm
cytoskeleton
spindle pole
In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.
Protein Attributes:
50:
MDDKTFTKEL | DQWVEQLNEC | KQLNENQVRT | LCEKAKEILT | KESNVQEVRC |
100:
PVTVCGDVHG | QFHDLMELFR | IGGKSPDTNY | LFMGDYVDRG | YYSVETVTLL |
150:
VALKVRYPER | ITILRGNHES | RQITQVYGFY | DECLRKYGNA | NVWKYFTDLF |
200:
DYLPLTALVD | GQIFCLHGGL | SPSIDTLDHI | RALDRLQEVP | HEGPMCDLLW |
250:
SDPDDRGGWG | ISPRGAGYTF | GQDISETFNH | ANGLTLVSRA | HQLVMEGYNW |
300:
CHDRNVVTIF | SAPNYCYRCG | NQAAIMELDD | TLKYSFLQFD | PAPRRGEPHV |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Pig
Mouse
Human
Rabbit
Bovine
ELISA Kit for Rabbit PP2A-beta
ELISA Kit for Rabbit PP2A-beta
ELISA Kit for Rabbit PP2A-beta
ELISA Kit for Rabbit PP2A-beta
ELISA Kit for Rabbit PP2A-beta
ELISA Kit for Rabbit PP2A-beta
CLIA Kit for Rabbit PP2A-beta
CLIA Kit for Rabbit PP2A-beta
CLIA Kit for Rabbit PP2A-beta
CLIA Kit for Rabbit PP2A-beta
CLIA Kit for Rabbit PP2A-beta
CLIA Kit for Rabbit PP2A-beta
Polyclonal Antibody for Rabbit PP2A-beta
Polyclonal Antibody for Rabbit PP2A-beta
Polyclonal Antibody for Rabbit PP2A-beta
Polyclonal Antibody for Rabbit PP2A-beta
Polyclonal Antibody for Rabbit PP2A-beta
Polyclonal Antibody for Rabbit PP2A-beta
Monoclonal Antibody for Rabbit PP2A-beta
Monoclonal Antibody for Rabbit PP2A-beta
Monoclonal Antibody for Rabbit PP2A-beta
Monoclonal Antibody for Rabbit PP2A-beta
Monoclonal Antibody for Rabbit PP2A-beta
Monoclonal Antibody for Rabbit PP2A-beta
Protein for Rabbit PP2A-beta
Protein for Rabbit PP2A-beta
Protein for Rabbit PP2A-beta
Protein for Rabbit PP2A-beta
Protein for Rabbit PP2A-beta
Protein for Rabbit PP2A-beta
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
New Zealand white .
tissue :
Skeletal muscle .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT TYR-307