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Index > Protein center > PPP2CB(Gene name) > Rabbit
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  • PPP2CB (Gene name),
  • Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform (Protein name ),  PP2AB_RABIT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    PPP2CB;
    Protein name:
    Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform(PP2A-beta);
    Alternative:

    Organism:
    Rabbit (Oryctolagus cuniculus). 
    General Annotation
    Sub Unit:
    PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Binds PPME1 (By similarity). May indirectly interact with SGOL1, most probably through regulatory B56 subunits. Found in a complex with at least ARL2, PPP2CB, PPP2R1A, PPP2R2A, PPP2R5E and TBCD. Interacts with TBCD.
    Function:
    PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
    Subcellular Location:
    Cytoplasm Nucleus Chromosome centromere Cytoplasm cytoskeleton spindle pole In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.
    Protein Attributes:
    Sequence length:
    309
    Sequence:
    50:
    MDDKTFTKEL | DQWVEQLNEC | KQLNENQVRT | LCEKAKEILT | KESNVQEVRC | 
    100:
    PVTVCGDVHG | QFHDLMELFR | IGGKSPDTNY | LFMGDYVDRG | YYSVETVTLL | 
    150:
    VALKVRYPER | ITILRGNHES | RQITQVYGFY | DECLRKYGNA | NVWKYFTDLF | 
    200:
    DYLPLTALVD | GQIFCLHGGL | SPSIDTLDHI | RALDRLQEVP | HEGPMCDLLW | 
    250:
    SDPDDRGGWG | ISPRGAGYTF | GQDISETFNH | ANGLTLVSRA | HQLVMEGYNW | 
    300:
    CHDRNVVTIF | SAPNYCYRCG | NQAAIMELDD | TLKYSFLQFD | PAPRRGEPHV | 
    309:
    TRRTPDYFL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rabbit PP2A-beta
    ELISA Kit for Rabbit PP2A-beta
    ELISA Kit for Rabbit PP2A-beta
    ELISA Kit for Rabbit PP2A-beta
    ELISA Kit for Rabbit PP2A-beta
    ELISA Kit for Rabbit PP2A-beta
    CLIA Kit for Rabbit PP2A-beta
    CLIA Kit for Rabbit PP2A-beta
    CLIA Kit for Rabbit PP2A-beta
    CLIA Kit for Rabbit PP2A-beta
    CLIA Kit for Rabbit PP2A-beta
    CLIA Kit for Rabbit PP2A-beta
    Polyclonal Antibody for Rabbit PP2A-beta
    Polyclonal Antibody for Rabbit PP2A-beta
    Polyclonal Antibody for Rabbit PP2A-beta
    Polyclonal Antibody for Rabbit PP2A-beta
    Polyclonal Antibody for Rabbit PP2A-beta
    Polyclonal Antibody for Rabbit PP2A-beta
    Monoclonal Antibody for Rabbit PP2A-beta
    Monoclonal Antibody for Rabbit PP2A-beta
    Monoclonal Antibody for Rabbit PP2A-beta
    Monoclonal Antibody for Rabbit PP2A-beta
    Monoclonal Antibody for Rabbit PP2A-beta
    Monoclonal Antibody for Rabbit PP2A-beta
    Protein for Rabbit PP2A-beta
    Protein for Rabbit PP2A-beta
    Protein for Rabbit PP2A-beta
    Protein for Rabbit PP2A-beta
    Protein for Rabbit PP2A-beta
    Protein for Rabbit PP2A-beta

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    References
    1. 1.
      "A second catalytic subunit of type-2A protein phosphatase from rabbit skeletal muscle."
      da Cruz e Silva O.B. , Cohen P.T.W.
      FEBS Lett.226:176-178(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: New Zealand white.
      tissue: Skeletal muscle.
    2. 2.
      "Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation."
      Chen J. , Martin B.L. , Brautigan D.L.
      Science257:1261-1264(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-307
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