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Index > Protein center > PPRC1(Gene name) > Human
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  • PPRC1 (Gene name),
  • Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 (Protein name ),  PPRC1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    PPRC1(KIAA0595);
    Protein name:
    Peroxisome proliferator-activated receptor gamma coactivator-related protein 1;
    Alternative:
    PGC-1-related coactivator(PRC);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with CREB1 and NRF1.
    Function:
    Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes.
    Subcellular Location:
    Nucleus Colocalizes with NRF1.
    Protein Attributes:
    Sequence length:
    1664
    Sequence:
    50:
    MAARRGRRDG | VAPPPSGGPG | PDPGGGARGS | GWGSRSQAPY | GTLGAVSGGE | 
    100:
    QVLLHEEAGD | SGFVSLSRLG | PSLRDKDLEM | EELMLQDETL | LGTMQSYMDA | 
    150:
    SLISLIEDFG | SLGESRLSLE | DQNEVSLLTA | LTEILDNADS | ENLSPFDSIP | 
    200:
    DSELLVSPRE | GSSLHKLLTL | SRTPPERDLI | TPVDPLGPST | GSSRGSGVEM | 
    250:
    SLPDPSWDFS | PPSFLETSSP | KLPSWRPPRS | RPRWGQSPPP | QQRSDGEEEE | 
    300:
    EVASFSGQIL | AGELDNCVSS | IPDFPMHLAC | PEEEDKATAA | EMAVPAAGDE | 
    350:
    SISSLSELVR | AMHPYCLPNL | THLASLEDEL | QEQPDDLTLP | EGCVVLEIVG | 
    400:
    QAATAGDDLE | IPVVVRQVSP | GPRPVLLDDS | LETSSALQLL | MPTLESETEA | 
    450:
    AVPKVTLCSE | KEGLSLNSEE | KLDSACLLKP | REVVEPVVPK | EPQNPPANAA | 
    500:
    PGSQRARKGR | KKKSKEQPAA | CVEGYARRLR | SSSRGQSTVG | TEVTSQVDNL | 
    550:
    QKQPQEELQK | ESGPLQGKGK | PRAWARAWAA | ALENSSPKNL | ERSAGQSSPA | 
    600:
    KEGPLDLYPK | LADTIQTNPI | PTHLSLVDSA | QASPMPVDSV | EADPTAVGPV | 
    650:
    LAGPVPVDPG | LVDLASTSSE | LVEPLPAEPV | LINPVLADSA | AVDPAVVPIS | 
    700:
    DNLPPVDAVP | SGPAPVDLAL | VDPVPNDLTP | VDPVLVKSRP | TDPRRGAVSS | 
    750:
    ALGGSAPQLL | VESESLDPPK | TIIPEVKEVV | DSLKIESGTS | ATTHEARPRP | 
    800:
    LSLSEYRRRR | QQRQAETEER | SPQPPTGKWP | SLPETPTGLA | DIPCLVIPPA | 
    850:
    PAKKTALQRS | PETPLEICLV | PVGPSPASPS | PEPPVSKPVA | SSPTEQVPSQ | 
    900:
    EMPLLARPSP | PVQSVSPAVP | TPPSMSAALP | FPAGGLGMPP | SLPPPPLQPP | 
    950:
    SLPLSMGPVL | PDPFTHYAPL | PSWPCYPHVS | PSGYPCLPPP | PTVPLVSGTP | 
    1000:
    GAYAVPPTCS | VPWAPPPAPV | SPYSSTCTYG | PLGWGPGPQH | APFWSTVPPP | 
    1050:
    PLPPASIGRA | VPQPKMESRG | TPAGPPENVL | PLSMAPPLSL | GLPGHGAPQT | 
    1100:
    EPTKVEVKPV | PASPHPKHKV | SALVQSPQMK | ALACVSAEGV | TVEEPASERL | 
    1150:
    KPETQETRPR | EKPPLPATKA | VPTPRQSTVP | KLPAVHPARL | RKLSFLPTPR | 
    1200:
    TQGSEDVVQA | FISEIGIEAS | DLSSLLEQFE | KSEAKKECPP | PAPADSLAVG | 
    1250:
    NSGGVDIPQE | KRPLDRLQAP | ELANVAGLTP | PATPPHQLWK | PLAAVSLLAK | 
    1300:
    AKSPKSTAQE | GTLKPEGVTE | AKHPAAVRLQ | EGVHGPSRVH | VGSGDHDYCV | 
    1350:
    RSRTPPKKMP | ALVIPEVGSR | WNVKRHQDIT | IKPVLSLGPA | APPPPCIAAS | 
    1400:
    REPLDHRTSS | EQADPSAPCL | APSSLLSPEA | SPCRNDMNTR | TPPEPSAKQR | 
    1450:
    SMRCYRKACR | SASPSSQGWQ | GRRGRNSRSV | SSGSNRTSEA | SSSSSSSSSS | 
    1500:
    SRSRSRSLSP | PHKRWRRSSC | SSSGRSRRCS | SSSSSSSSSS | SSSSSSSSSR | 
    1550:
    SRSRSPSPRR | RSDRRRRYSS | YRSHDHYQRQ | RVLQKERAIE | ERRVVFIGKI | 
    1600:
    PGRMTRSELK | QRFSVFGEIE | ECTIHFRVQG | DNYGFVTYRY | AEEAFAAIES | 
    1650:
    GHKLRQADEQ | PFDLCFGGRR | QFCKRSYSDL | DSNREDFDPA | PVKSKFDSLD | 
    1664:
    FDTLLKQAQK | NLRR
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    KEGG:
    String:
    UniGene:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
    Cat.:
    E2188h
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
    Cat.:
    E2188m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
    Cat.:
    U2188m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
    Cat.:
    U2188h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
    Cat.:
    P2188Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
    Cat.:
    P2188Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
    Monoclonal Antibody for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
    Protein for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
    Protein for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Pgc-1-related coactivator, a novel, serum-inducible coactivator of nuclear respiratory factor 1-dependent transcription in mammalian cells."
      Andersson U. , Scarpulla R.C.
      Mol. Cell. Biol.21:3738-3749(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH NRF1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    2. 2.
      "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro."
      Nagase T. , Ishikawa K. , Miyajima N. , Tanaka A. , Kotani H. , Nomura N. , Ohara O.
      DNA Res.5:31-39(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Brain.
    3. 3.
      "Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones."
      Nakajima D. , Okazaki N. , Yamakawa H. , Kikuno R. , Ohara O. , Nagase T.
      DNA Res.9:99-106(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
    4. 4.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 998-1664 (ISOFORM 1);VARIANT ARG-834
      tissue: Placenta.
      tissue: Uterus.
    6. 6.
      "PGC-1-related coactivator and targets are upregulated in thyroid oncocytoma."
      Savagner F. , Mirebeau D. , Jacques C. , Guyetant S. , Morgan C. , Franc B. , Reynier P. , Malthiery Y.
      Biochem. Biophys. Res. Commun.310:779-784(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
    7. 7.
      "PGC-1-related coactivator: immediate early expression and characterization of a CREB/NRF-1 binding domain associated with cytochrome c promoter occupancy and respiratory growth."
      Vercauteren K. , Pasko R.A. , Gleyzer N. , Marino V.M. , Scarpulla R.C.
      Mol. Cell. Biol.26:7409-7419(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CREB1 AND NRF1;INDUCTION
    8. 8.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-536;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1411 AND SER-1413;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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