Gene name:
PPRC1 (KIAA0595) ;
Protein name:
Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 ;
Alternative:
PGC-1-related coactivator (PRC) ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Interacts with CREB1 and NRF1.
Function:
Acts as a coactivator during transcriptional activation of nuclear genes related to mitochondrial biogenesis and cell growth. Involved in the transcription coactivation of CREB and NRF1 target genes.
Subcellular Location:
Nucleus
Colocalizes with NRF1.
Protein Attributes:
50:
MAARRGRRDG | VAPPPSGGPG | PDPGGGARGS | GWGSRSQAPY | GTLGAVSGGE |
100:
QVLLHEEAGD | SGFVSLSRLG | PSLRDKDLEM | EELMLQDETL | LGTMQSYMDA |
150:
SLISLIEDFG | SLGESRLSLE | DQNEVSLLTA | LTEILDNADS | ENLSPFDSIP |
200:
DSELLVSPRE | GSSLHKLLTL | SRTPPERDLI | TPVDPLGPST | GSSRGSGVEM |
250:
SLPDPSWDFS | PPSFLETSSP | KLPSWRPPRS | RPRWGQSPPP | QQRSDGEEEE |
300:
EVASFSGQIL | AGELDNCVSS | IPDFPMHLAC | PEEEDKATAA | EMAVPAAGDE |
350:
SISSLSELVR | AMHPYCLPNL | THLASLEDEL | QEQPDDLTLP | EGCVVLEIVG |
400:
QAATAGDDLE | IPVVVRQVSP | GPRPVLLDDS | LETSSALQLL | MPTLESETEA |
450:
AVPKVTLCSE | KEGLSLNSEE | KLDSACLLKP | REVVEPVVPK | EPQNPPANAA |
500:
PGSQRARKGR | KKKSKEQPAA | CVEGYARRLR | SSSRGQSTVG | TEVTSQVDNL |
550:
QKQPQEELQK | ESGPLQGKGK | PRAWARAWAA | ALENSSPKNL | ERSAGQSSPA |
600:
KEGPLDLYPK | LADTIQTNPI | PTHLSLVDSA | QASPMPVDSV | EADPTAVGPV |
650:
LAGPVPVDPG | LVDLASTSSE | LVEPLPAEPV | LINPVLADSA | AVDPAVVPIS |
700:
DNLPPVDAVP | SGPAPVDLAL | VDPVPNDLTP | VDPVLVKSRP | TDPRRGAVSS |
750:
ALGGSAPQLL | VESESLDPPK | TIIPEVKEVV | DSLKIESGTS | ATTHEARPRP |
800:
LSLSEYRRRR | QQRQAETEER | SPQPPTGKWP | SLPETPTGLA | DIPCLVIPPA |
850:
PAKKTALQRS | PETPLEICLV | PVGPSPASPS | PEPPVSKPVA | SSPTEQVPSQ |
900:
EMPLLARPSP | PVQSVSPAVP | TPPSMSAALP | FPAGGLGMPP | SLPPPPLQPP |
950:
SLPLSMGPVL | PDPFTHYAPL | PSWPCYPHVS | PSGYPCLPPP | PTVPLVSGTP |
1000:
GAYAVPPTCS | VPWAPPPAPV | SPYSSTCTYG | PLGWGPGPQH | APFWSTVPPP |
1050:
PLPPASIGRA | VPQPKMESRG | TPAGPPENVL | PLSMAPPLSL | GLPGHGAPQT |
1100:
EPTKVEVKPV | PASPHPKHKV | SALVQSPQMK | ALACVSAEGV | TVEEPASERL |
1150:
KPETQETRPR | EKPPLPATKA | VPTPRQSTVP | KLPAVHPARL | RKLSFLPTPR |
1200:
TQGSEDVVQA | FISEIGIEAS | DLSSLLEQFE | KSEAKKECPP | PAPADSLAVG |
1250:
NSGGVDIPQE | KRPLDRLQAP | ELANVAGLTP | PATPPHQLWK | PLAAVSLLAK |
1300:
AKSPKSTAQE | GTLKPEGVTE | AKHPAAVRLQ | EGVHGPSRVH | VGSGDHDYCV |
1350:
RSRTPPKKMP | ALVIPEVGSR | WNVKRHQDIT | IKPVLSLGPA | APPPPCIAAS |
1400:
REPLDHRTSS | EQADPSAPCL | APSSLLSPEA | SPCRNDMNTR | TPPEPSAKQR |
1450:
SMRCYRKACR | SASPSSQGWQ | GRRGRNSRSV | SSGSNRTSEA | SSSSSSSSSS |
1500:
SRSRSRSLSP | PHKRWRRSSC | SSSGRSRRCS | SSSSSSSSSS | SSSSSSSSSR |
1550:
SRSRSPSPRR | RSDRRRRYSS | YRSHDHYQRQ | RVLQKERAIE | ERRVVFIGKI |
1600:
PGRMTRSELK | QRFSVFGEIE | ECTIHFRVQG | DNYGFVTYRY | AEEAFAAIES |
1650:
GHKLRQADEQ | PFDLCFGGRR | QFCKRSYSDL | DSNREDFDPA | PVKSKFDSLD |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
ELISA Kit for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
ELISA Kit for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
CLIA Kit for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
CLIA Kit for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
Polyclonal Antibody for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
Polyclonal Antibody for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
Monoclonal Antibody for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
Monoclonal Antibody for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
Protein for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
Protein for Human Peroxisome proliferator-activated receptor gamma coactivator-related protein 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;INTERACTION WITH NRF1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
tissue :
Brain .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SEQUENCE REVISION
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 998-1664 (ISOFORM 1);VARIANT ARG-834
tissue :
Placenta .
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Uterus .
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;INTERACTION WITH CREB1 AND NRF1;INDUCTION
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-536;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1411 AND SER-1413;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]