PFN2 ELISA Kit for Human(Homo sapiens) | EIAab.comPFN2 ELISA Kit for Human(Homo sapiens)

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Index > Protein center > PFN2(Gene name) > Human

PFN2 (Gene name),

Profilin-2 (Protein name ), PROF2_HUMAN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

PFN2;

Protein name:

Profilin-2;

Alternative:

Profilin II;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Occurs in many kinds of cells as a complex with monomeric actin in a 1:1 ratio.

Function:

Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

Subcellular Location:

Cytoplasm cytoskeleton

Protein Attributes:

Sequence length:

140

Sequence:

50:

100:

140:

VAVGRAGRVL | VFVMGKEGVH | GGGLNKKAYS | MAKYLRDSGF |

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P35080

UniGene:

Hs.91747

Pfam:

PF00235

STRING:

9606.ENSP00000239940

MIM:

176590

String:

P35080

KEGG:

hsa:5217

Uniprot:

P35080

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ELISA Kit for Human Profilin-2

Cat.:

E0347h

Price:

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Manual:

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MSDS:

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Packing:

96T

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ELISA Kit for Human Profilin-2

Cat.:

E0347r

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MSDS:

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Packing:

96T

ELISA Kit for Human Profilin-2

Cat.:

E0347b

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MSDS:

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Packing:

96T

ELISA Kit for Human Profilin-2

Cat.:

E0347m

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MSDS:

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Packing:

96T

CLIA Kit for Human Profilin-2

Cat.:

U0347h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Profilin-2

Cat.:

U0347m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Human Profilin-2

Cat.:

U0347b

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MSDS:

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Packing:

96T

CLIA Kit for Human Profilin-2

Cat.:

U0347r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Human Profilin-2

Cat.:

P0347Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Profilin-2

Cat.:

P0347Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Human Profilin-2

Cat.:

P0347Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Human Profilin-2

Protein for Human Profilin-2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and expression of a novel human profilin variant, profilin II."
Honore B. , Madsen P.S. , Andersen A.H. , Leffers H.
FEBS Lett.330:151-155(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM IIB)
tissue: Epithelium.
2.

"Profilin II is alternatively spliced, resulting in profilin isoforms that are differentially expressed and have distinct biochemical properties."
Lambrechts A. , Braun A. , Jonckheere V. , Aszodi A. , Lanier L.M. , Robbens J. , Van Colen I. , Vandekerckhove J. , Faessler R. , Ampe C.
Mol. Cell. Biol.20:8209-8219(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM IIA)
tissue: Brain.
3.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS IIA AND IIB)
4.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-09) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS IIA AND IIB)
tissue: Brain.
tissue: Lung.
tissue: Spinal cord.
6.

Lubec G. , Chen W.-Q. , Sun Y.
Submitted (2008-12) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 30-69; 76-89; 92-105 AND 109-116;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Fetal brain cortex.
7.

"Distinct biochemical characteristics of the two human profilin isoforms."
Gieselmann R. , Kwiatkowski D.J. , Janmey P.A. , Witke W.
Eur. J. Biochem.229:621-628(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION
8.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
9.

"Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features."
Bienvenut W.V. , Sumpton D. , Martinez A. , Lilla S. , Espagne C. , Meinnel T. , Giglione C.
Mol. Cell. Proteomics11:M111.015131-M111.015131(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT ALA-2;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
10.

"X-ray structure determination of human profilin II: a comparative structural analysis of human profilins."
Nodelman I.M. , Bowman G.D. , Lindberg U. , Schutt C.E.
J. Mol. Biol.294:1271-1285(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.2 ANGSTROMS)

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