Adssl1 ELISA Kit for Mouse(Mus musculus) | EIAab.comAdssl1 ELISA Kit for Mouse(Mus musculus)

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Adssl1 (Gene name),

Adenylosuccinate synthetase isozyme 1 (Protein name ), PURA1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Adssl1(Adss1);

Protein name:

Adenylosuccinate synthetase isozyme 1(AMPSase 1;AdSS 1);

Alternative:

Adenylosuccinate synthetase, muscle isozyme(M-type adenylosuccinate synthetase);Adenylosuccinate synthetase, basic isozyme;IMP--aspartate ligase 1;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homodimer.

Function:

Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.

Subcellular Location:

Cytoplasm Membrane Peripheral membrane protein Partially associated with particulate fractions.

Protein Attributes:

Sequence length:

457

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

457:

ESMIQLF

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

P28650

KEGG:

mmu:11565

String:

P28650

Pfam:

PF00709

UniGene:

Mm.3440

Uniprot:

P28650

FOR

ELISA Kit for Mouse AMPSase 1

CLIA Kit for Mouse AMPSase 1

Polyclonal Antibody for Mouse AMPSase 1

Monoclonal Antibody for Mouse AMPSase 1

Protein for Mouse AMPSase 1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Molecular cloning and expression of a mouse muscle cDNA encoding adenylosuccinate synthetase."
Guicherit O.M. , Rudolph F.B. , Kellems R.E. , Cooper B.F.
J. Biol. Chem.266:22582-22587(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
tissue: Muscle.
2.

"Amplification of an adenylosuccinate synthetase gene in alanosine-resistant murine T-lymphoma cells. Molecular cloning of a cDNA encoding the 'non-muscle' isozyme."
Guicherit O.M. , Cooper B.F. , Rudolph F.B. , Kellems R.E.
J. Biol. Chem.269:4488-4496(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SEQUENCE REVISION
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
strain: Czech II.
tissue: Mammary tumor.
4.

"Variations in the response of mouse isozymes of adenylosuccinate synthetase to inhibitors of physiological relevance."
Borza T. , Iancu C.V. , Pike E. , Honzatko R.B. , Fromm H.J.
J. Biol. Chem.278:6673-6679(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;BIOPHYSICOCHEMICAL PROPERTIES
5.

"Recombinant mouse muscle adenylosuccinate synthetase: overexpression, kinetics, and crystal structure."
Iancu C.V. , Borza T. , Choe J.Y. , Fromm H.J. , Honzatko R.B.
J. Biol. Chem.276:42146-42152(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS)
6.

"IMP, GTP, and 6-phosphoryl-IMP complexes of recombinant mouse muscle adenylosuccinate synthetase."
Iancu C.V. , Borza T. , Fromm H.J. , Honzatko R.B.
J. Biol. Chem.277:26779-26787(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS) IN COMPLEX WITH IMP AND GTP
7.

"Feedback inhibition and product complexes of recombinant mouse muscle adenylosuccinate synthetase."
Iancu C.V. , Borza T. , Fromm H.J. , Honzatko R.B.
J. Biol. Chem.277:40536-40543(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS)
8.

"Cavitation as a mechanism of substrate discrimination by adenylosuccinate synthetases."
Iancu C.V. , Zhou Y. , Borza T. , Fromm H.J. , Honzatko R.B.
Biochemistry45:11703-11711(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.40 ANGSTROMS)

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