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Index > Protein center > PXDN(Gene name) > Human
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  • PXDN (Gene name),
  • Peroxidasin homolog (Protein name ),  PXDN_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Citations  (1)
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  • Gene name:
    PXDN(KIAA0230;MG50;PRG2;VPO;VPO1);
    Protein name:
    Peroxidasin homolog;
    Alternative:
    Vascular peroxidase 1;Melanoma-associated antigen MG50;p53-responsive gene 2 protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Displays low peroxidase activity and is likely to participate in H(2)O(2) metabolism and peroxidative reactions in the cardiovascular system. Plays a role in extracellular matrix formation.
    Subcellular Location:
    Secreted extracellular space extracellular matrix Enriched in the peritubular space of fibrotic kidneys.
    Protein Attributes:
    Sequence length:
    1479
    Sequence:
    50:
    MAKRSRGPGR | RCLLALVLFC | AWGTLAVVAQ | KPGAGCPSRC | LCFRTTVRCM | 
    100:
    HLLLEAVPAV | APQTSILDLR | FNRIREIQPG | AFRRLRNLNT | LLLNNNQIKR | 
    150:
    IPSGAFEDLE | NLKYLYLYKN | EIQSIDRQAF | KGLASLEQLY | LHFNQIETLD | 
    200:
    PDSFQHLPKL | ERLFLHNNRI | THLVPGTFNH | LESMKRLRLD | SNTLHCDCEI | 
    250:
    LWLADLLKTY | AESGNAQAAA | ICEYPRRIQG | RSVATITPEE | LNCERPRITS | 
    300:
    EPQDADVTSG | NTVYFTCRAE | GNPKPEIIWL | RNNNELSMKT | DSRLNLLDDG | 
    350:
    TLMIQNTQET | DQGIYQCMAK | NVAGEVKTQE | VTLRYFGSPA | RPTFVIQPQN | 
    400:
    TEVLVGESVT | LECSATGHPP | PRISWTRGDR | TPLPVDPRVN | ITPSGGLYIQ | 
    450:
    NVVQGDSGEY | ACSATNNIDS | VHATAFIIVQ | ALPQFTVTPQ | DRVVIEGQTV | 
    500:
    DFQCEAKGNP | PPVIAWTKGG | SQLSVDRRHL | VLSSGTLRIS | GVALHDQGQY | 
    550:
    ECQAVNIIGS | QKVVAHLTVQ | PRVTPVFASI | PSDTTVEVGA | NVQLPCSSQG | 
    600:
    EPEPAITWNK | DGVQVTESGK | FHISPEGFLT | INDVGPADAG | RYECVARNTI | 
    650:
    GSASVSMVLS | VNVPDVSRNG | DPFVATSIVE | AIATVDRAIN | STRTHLFDSR | 
    700:
    PRSPNDLLAL | FRYPRDPYTV | EQARAGEIFE | RTLQLIQEHV | QHGLMVDLNG | 
    750:
    TSYHYNDLVS | PQYLNLIANL | SGCTAHRRVN | NCSDMCFHQK | YRTHDGTCNN | 
    800:
    LQHPMWGASL | TAFERLLKSV | YENGFNTPRG | INPHRLYNGH | ALPMPRLVST | 
    850:
    TLIGTETVTP | DEQFTHMLMQ | WGQFLDHDLD | STVVALSQAR | FSDGQHCSNV | 
    900:
    CSNDPPCFSV | MIPPNDSRAR | SGARCMFFVR | SSPVCGSGMT | SLLMNSVYPR | 
    950:
    EQINQLTSYI | DASNVYGSTE | HEARSIRDLA | SHRGLLRQGI | VQRSGKPLLP | 
    1000:
    FATGPPTECM | RDENESPIPC | FLAGDHRANE | QLGLTSMHTL | WFREHNRIAT | 
    1050:
    ELLKLNPHWD | GDTIYYETRK | IVGAEIQHIT | YQHWLPKILG | EVGMRTLGEY | 
    1100:
    HGYDPGINAG | IFNAFATAAF | RFGHTLVNPL | LYRLDENFQP | IAQDHLPLHK | 
    1150:
    AFFSPFRIVN | EGGIDPLLRG | LFGVAGKMRV | PSQLLNTELT | ERLFSMAHTV | 
    1200:
    ALDLAAINIQ | RGRDHGIPPY | HDYRVYCNLS | AAHTFEDLKN | EIKNPEIREK | 
    1250:
    LKRLYGSTLN | IDLFPALVVE | DLVPGSRLGP | TLMCLLSTQF | KRLRDGDRLW | 
    1300:
    YENPGVFSPA | QLTQIKQTSL | ARILCDNADN | ITRVQSDVFR | VAEFPHGYGS | 
    1350:
    CDEIPRVDLR | VWQDCCEDCR | TRGQFNAFSY | HFRGRRSLEF | SYQEDKPTKK | 
    1400:
    TRPRKIPSVG | RQGEHLSNST | SAFSTRSDAS | GTNDFREFVL | EMQKTITDLR | 
    1450:
    TQIKKLESRL | STTECVDAGG | ESHANNTKWK | KDACTICECK | DGQVTCFVEA | 
    1479:
    CPPATCAVPV | NIPGACCPVC | LQKRAEEKP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    String:
    MIM:
    SMR:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Peroxidasin homolog
    Cat.:
    E0978h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Peroxidasin homolog
    Cat.:
    E0978m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Peroxidasin homolog
    Cat.:
    U0978h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Peroxidasin homolog
    Cat.:
    U0978m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Peroxidasin homolog
    Cat.:
    P0978Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Peroxidasin homolog
    Cat.:
    P0978Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Peroxidasin homolog
    Monoclonal Antibody for Human Peroxidasin homolog
    Protein for Human Peroxidasin homolog
    Protein for Human Peroxidasin homolog

    R&D Technical Data
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Precision

    Intra-Assay CV: ≤4.4

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery

    Inter-Assay CV: ≤7.9

    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Citations
    [1].
    Ji Fei Zhang , Fu Sheng Zhao, Geng Wu, Qing Fei Kong, Bo Sun, Jingyan Cao, Yao Zhang, Jing Hua Wang, Jing Zhang, Xu Dong Jin , Hu Lun Li
    References
    1. 1.
      "Isolation of differentially expressed cDNAs from p53-dependent apoptotic cells: activation of the human homologue of the Drosophila peroxidasin gene."
      Horikoshi N. , Cong J. , Kley N. , Shenk T.
      Biochem. Biophys. Res. Commun.261:864-869(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INDUCTION;TISSUE SPECIFICITY
    2. 2.
      "A novel melanoma gene (MG50) encoding the interleukin 1 receptor antagonist and six epitopes recognized by human cytolytic T lymphocytes."
      Mitchell M.S. , Kan-Mitchell J. , Minev B. , Edman C. , Deans R.J.
      Cancer Res.60:6448-6456(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
    3. 3.
      "Identification and characterization of VPO1, a new animal heme-containing peroxidase."
      Cheng G. , Salerno J.C. , Cao Z. , Pagano P.J. , Lambeth J.D.
      Free Radic. Biol. Med.45:1682-1694(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);3D-STRUCTURE MODELING;FUNCTION;CATALYTIC ACTIVITY;BIOPHYSICOCHEMICAL PROPERTIES;HEME COFACTOR;TISSUE SPECIFICITY
    4. 4.
      "Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain."
      Nagase T. , Seki N. , Ishikawa K. , Ohira M. , Kawarabayasi Y. , Ohara O. , Tanaka A. , Kotani H. , Miyajima N. , Nomura N.
      DNA Res.3:321-329(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Bone marrow.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 6-1479 (ISOFORM 2)
      tissue: Chondrosarcoma.
    7. 7.
      "Large-scale phosphoproteome analysis of human liver tissue by enrichment and fractionation of phosphopeptides with strong anion exchange chromatography."
      Han G. , Ye M. , Zhou H. , Jiang X. , Feng S. , Jiang X. , Tian R. , Wan D. , Zou H. , Gu J.
      Proteomics8:1346-1361(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-1176 AND SER-1180;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: SUBCELLULAR LOCATION
    9. 9.
      "Peroxidasin is secreted and incorporated into the extracellular matrix of myofibroblasts and fibrotic kidney."
      Peterfi Z. , Donko A. , Orient A. , Sum A. , Prokai A. , Molnar B. , Vereb Z. , Rajnavolgyi E. , Kovacs K.J. , Muller V. , Szabo A.J. , Geiszt M.
      Am. J. Pathol.175:725-735(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;CATALYTIC ACTIVITY;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;INDUCTION BY TGFB1
    10. 10.
      "Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry."
      Chen R. , Jiang X. , Sun D. , Han G. , Wang F. , Ye M. , Wang L. , Zou H.
      J. Proteome Res.8:651-661(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-1178
      tissue: Liver.
    11. 11.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN COPOA;VARIANT COPOA CYS-880
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