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Index > Protein center > UQCRC2(Gene name) > Human
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  • UQCRC2 (Gene name),
  • Cytochrome b-c1 complex subunit 2, mitochondrial (Protein name ),  QCR2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    UQCRC2;
    Protein name:
    Cytochrome b-c1 complex subunit 2, mitochondrial;
    Alternative:
    Core protein II;Complex III subunit 2;Ubiquinol-cytochrome-c reductase complex core protein 2;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    The bc1 complex contains 11 subunits: 3 respiratory subunits (cytochrome b, cytochrome c1 and Rieske/UQCRFS1), 2 core proteins (UQCRC1/QCR1 and UQCRC2/QCR2) and 6 low-molecular weight proteins (UQCRH/QCR6, UQCRB/QCR7, UQCRQ/QCR8, UQCR10/QCR9, UQCR11/QCR10 and a cleavage product of Rieske/UQCRFS1).
    Function:
    This is a component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is part of the mitochondrial respiratory chain. The core protein 2 is required for the assembly of the complex.
    Subcellular Location:
    Mitochondrion inner membrane Peripheral membrane protein Matrix side
    Protein Attributes:
    Sequence length:
    453
    Sequence:
    50:
    MKLLTRAGSF | SRFYSLKVAP | KVKATAAPAG | APPQPQDLEF | TKLPNGLVIA | 
    100:
    SLENYSPVSR | IGLFIKAGSR | YEDFSNLGTT | HLLRLTSSLT | TKGASSFKIT | 
    150:
    RGIEAVGGKL | SVTATRENMA | YTVECLRGDV | DILMEFLLNV | TTAPEFRRWE | 
    200:
    VADLQPQLKI | DKAVAFQNPQ | THVIENLHAA | AYRNALANPL | YCPDYRIGKV | 
    250:
    TSEELHYFVQ | NHFTSARMAL | IGLGVSHPVL | KQVAEQFLNM | RGGLGLSGAK | 
    300:
    ANYRGGEIRE | QNGDSLVHAA | FVAESAVAGS | AEANAFSVLQ | HVLGAGPHVK | 
    350:
    RGSNTTSHLH | QAVAKATQQP | FDVSAFNASY | SDSGLFGIYT | ISQATAAGDV | 
    400:
    IKAAYNQVKT | IAQGNLSNTD | VQAAKNKLKA | GYLMSVESSE | CFLEEVGSQA | 
    450:
    LVAGSYMPPS | TVLQQIDSVA | NADIINAAKK | FVSGQKSMAA | SGNLGHTPFV | 
    453:
    DEL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    KEGG:
    SMR:
    UniGene:
    MIM:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    ELISA Kit for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    ELISA Kit for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    ELISA Kit for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    CLIA Kit for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    CLIA Kit for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    CLIA Kit for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    CLIA Kit for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    Polyclonal Antibody for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    Polyclonal Antibody for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    Polyclonal Antibody for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    Polyclonal Antibody for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    Monoclonal Antibody for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    Monoclonal Antibody for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    Monoclonal Antibody for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    Monoclonal Antibody for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    Protein for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    Protein for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    Protein for Human Cytochrome b-c1 complex subunit 2, mitochondrial
    Protein for Human Cytochrome b-c1 complex subunit 2, mitochondrial

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    Precision
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    Linearity
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    References
    1. 1.
      "Complementary DNA encoding core protein II of human mitochondrial cytochrome bc1 complex. Substantial diversity in deduced primary structure from its yeast counterpart."
      Hosokawa Y. , Suzuki H. , Toda H. , Nishikimi M. , Ozawa T.
      J. Biol. Chem.264:13483-13488(1989) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT GLN-183
    2. 2.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Uterus.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
      tissue: Skin.
    5. 5.
      Lubec G. , Vishwanath V.
      Submitted (2007-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 43-60; 71-84 AND 200-217;IDENTIFICATION BY MASS SPECTROMETRY
      tissue: Brain.
      tissue: Cajal-Retzius cell.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    7. 7.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT [LARGE SCALE ANALYSIS] TYR-208
    8. 8.
      "Mitochondrial complex III deficiency caused by a homozygous UQCRC2 mutation presenting with neonatal-onset recurrent metabolic decompensation."
      Miyake N. , Yano S. , Sakai C. , Hatakeyama H. , Matsushima Y. , Shiina M. , Watanabe Y. , Bartley J. , Abdenur J.E. , Wang R.Y. , Chang R. , Tsurusaki Y. , Doi H. , Nakashima M. , Saitsu H. , Ogata K. , Goto Y. , Matsumoto N.
      Hum. Mutat.34:446-452(2013) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT MC3DN5 TRP-183
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