KRAS ELISA Kit for Human(Homo sapiens) | EIAab.comKRAS ELISA Kit for Human(Homo sapiens)

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > KRAS(Gene name) > Human

KRAS (Gene name),

GTPase KRas (Protein name ), RASK_HUMAN from NCBI database.

top

General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

Feedback

Gene name:

KRAS(KRAS2;RASK2);

Protein name:

GTPase KRas;

Alternative:

Ki-Ras;K-Ras 2;c-Ki-ras;c-K-ras;

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts with PHLPP. Interacts (active GTP-bound form preferentially) with RGS14.

Function:

Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.

Subcellular Location:

Cell membrane Lipid-anchor Cytoplasmic side

Protein Attributes:

Sequence length:

189

Sequence:

50:

100:

150:

189:

RVEDAFYTLV | REIRQYRLKK | ISKEEKTPGC | VKIKKCIIM

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

STRING:

9606.ENSP00000256078

KEGG:

hsa:3845

Pfam:

PF00071

UniGene:

Hs.37003

MIM:

115150

String:

P01116

MIM:

190070

SMR:

P01116

Uniprot:

P01116

FOR

ELISA Kit for Human GTPase KRas

CLIA Kit for Human GTPase KRas

Polyclonal Antibody for Human GTPase KRas

Monoclonal Antibody for Human GTPase KRas

Protein for Human GTPase KRas

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Structure and organization of the human Ki-ras proto-oncogene and a related processed pseudogene."
McGrath J.P. , Capon D.J. , Smith D.H. , Chen E.Y. , Seeburg P.H. , Goeddel D.V. , Levinson A.D.
Nature304:501-506(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 2A AND 2B)
2.

"Structure of the Ki-ras gene of the human lung carcinoma cell line Calu-1."
Shimizu K. , Birnbaum D. , Ruley M.A. , Fasano O. , Suard Y. , Edlund L. , Taparowsky E. , Goldfarb M. , Wigler M.
Nature304:497-500(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 2A AND 2B)
tissue: Lung carcinoma.
3.

"Activation of Ki-ras2 gene in human colon and lung carcinomas by two different point mutations."
Capon D.J. , Seeburg P.H. , McGrath J.P. , Hayflick J.S. , Edman U. , Levinson A.D. , Goeddel D.V.
Nature304:507-513(1983) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 2A AND 2B)
tissue: Colon carcinoma.
tissue: Lung.
4.

"Human colon carcinoma Ki-ras2 oncogene and its corresponding proto-oncogene."
McCoy M.S. , Bargmann C.I. , Weinberg R.A.
Mol. Cell. Biol.4:1577-1582(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORMS 2A AND 2B);VARIANT COLON CANCER VAL-12
tissue: Colon carcinoma.
5.

"The c-K-ras gene and human cancer (review)."
Kahn S. , Yamamoto F. , Almoguera C. , Winter E. , Forrester K. , Jordano J. , Perucho M.
Anticancer Res.7:639-652(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2B)
6.

"cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
Puhl H.L. III , Ikeda S.R. , Aronstam R.S.
Submitted (2002-03) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2B)
tissue: Brain.
7.

"Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
Submitted (2003-05) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2B);VARIANT LUNG CARCINOMA HIS-61
8.

"Complete sequencing and characterization of 21,243 full-length human cDNAs."
Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2B)
tissue: Testis.
9.

SeattleSNPs variation discovery resource
Submitted (2007-12) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
10.

Mural R.J. , Istrail S. , Sutton G.G. , Florea L. , Halpern A.L. , Mobarry C.M. , Lippert R. , Walenz B. , Shatkay H. , Dew I. , Miller J.R. , Flanigan M.J. , Edwards N.J. , Bolanos R. , Fasulo D. , Halldorsson B.V. , Hannenhalli S. , Turner R. , more...
Submitted (2005-07) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
11.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2B);VARIANT LUNG CARCINOMA HIS-61
tissue: Lung carcinoma.
12.

"Isolation of transforming sequences of two human lung carcinomas: structural and functional analysis of the activated c-K-ras oncogenes."
Nakano H. , Yamamoto F. , Neville C. , Evans D. , Mizuno T. , Perucho M.
Proc. Natl. Acad. Sci. U.S.A.81:71-75(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-37;VARIANT LUNG CARCINOMA CYS-12
tissue: Lung carcinoma.
13.

"Activation of the c-K-ras oncogene in a human pancreas carcinoma."
Hirai H. , Okabe T. , Anraku Y. , Fujisawa M. , Urabe A. , Takaku F.
Biochem. Biophys. Res. Commun.127:168-174(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-96
tissue: Pancreatic carcinoma.
14.

"Activated c-Ha-ras oncogene with a guanine to thymine transversion at the twelfth codon in a human stomach cancer cell line."
Deng G. , Lu Y. , Chen S. , Miao J. , Lu G. , Li H. , Cai H. , Xu X. , Zheng E. , Liu P.
Cancer Res.47:3195-3198(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-37;VARIANT GASC VAL-12
15.

"Malignant activation of a K-ras oncogene in lung carcinoma but not in normal tissue of the same patient."
Santos E. , Martin-Zanca D. , Reddy P.E. , Pierotti M.A. , Porta G. , Barbacid M.
Science223:661-664(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-36;VARIANT BLADDER/LUNG CANCER ARG-12
tissue: Lung carcinoma.
16.

"Essential region for transforming activity of human c-Ha-ras-1."
Sekiya T. , Tokunaga A. , Fushimi M.
Jpn. J. Cancer Res.76:787-791(1985) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-37
17.

Bienvenut W.V. , Calvo F. , Kolch W.
Submitted (2008-02) to the UniProtKB

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 1-41; 43-147 AND 150-161;CLEAVAGE OF INITIATOR METHIONINE;ACETYLATION AT MET-1 AND THR-2;IDENTIFICATION BY MASS SPECTROMETRY
tissue: Cervix carcinoma.
18.

"Activation of a human c-K-ras oncogene."
Yamamoto F. , Perucho M.
Nucleic Acids Res.12:8873-8885(1984) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 38-96
tissue: Lung carcinoma.
19.

"Initial characterization of the human central proteome."
Burkard T.R. , Planyavsky M. , Kaupe I. , Breitwieser F.P. , Buerckstuemmer T. , Bennett K.L. , Superti-Furga G. , Colinge J.
BMC Syst. Biol.5:17-17(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
20.

"Regulation of RAS oncogenicity by acetylation."
Yang M.H. , Nickerson S. , Kim E.T. , Liot C. , Laurent G. , Spang R. , Philips M.R. , Shan Y. , Shaw D.E. , Bar-Sagi D. , Haigis M.C. , Haigis K.M.
Proc. Natl. Acad. Sci. U.S.A.109:10843-10848(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION AT LYS-104;VARIANT VAL-12;FUNCTION;ENZYME REGULATION
21.

"Small molecule inhibition of the KRAS-PDE? interaction impairs oncogenic KRAS signalling."
Zimmermann G. , Papke B. , Ismail S. , Vartak N. , Chandra A. , Hoffmann M. , Hahn S.A. , Triola G. , Wittinghofer A. , Bastiaens P.I. , Waldmann H.
Nature497:638-642(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH PDE6D
22.

"Discovery of small molecules that bind to K-Ras and inhibit Sos-mediated activation."
Sun Q. , Burke J.P. , Phan J. , Burns M.C. , Olejniczak E.T. , Waterson A.G. , Lee T. , Rossanese O.W. , Fesik S.W.
Angew. Chem. Int. Ed. Engl.51:6140-6143(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.35 ANGSTROMS) OF 1-164 IN COMPLEX WITH THE GTP ANALOG GUANOSINE-5'-DIPHOSPHATE;ENZYME REGULATION
23.

"Small-molecule ligands bind to a distinct pocket in Ras and inhibit SOS-mediated nucleotide exchange activity."
Maurer T. , Garrenton L.S. , Oh A. , Pitts K. , Anderson D.J. , Skelton N.J. , Fauber B.P. , Pan B. , Malek S. , Stokoe D. , Ludlam M.J. , Bowman K.K. , Wu J. , Giannetti A.M. , Starovasnik M.A. , Mellman I. , Jackson P.K. , Rudolph J. , more...
Proc. Natl. Acad. Sci. U.S.A.109:5299-5304(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 2-164 IN COMPLEX WITH GTP ANALOGS AND MAGNESIUM;FUNCTION;ENZYME REGULATION;INTERACTION WITH SOS1;SUBCELLULAR LOCATION
24.

"The human c-Kirsten ras gene is activated by a novel mutation in codon 13 in the breast carcinoma cell line MDA-MB231."
Kozma S.C. , Bogaard M.E. , Buser K. , Saurer S.M. , Bos J.L. , Groner B. , Hynes N.E.
Nucleic Acids Res.15:5963-5971(1987) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BREAST CANCER ASP-13
25.

"Detection of a rare point mutation in Ki-ras of a human bladder cancer xenograft by polymerase chain reaction and direct sequencing."
Grimmond S.M. , Raghavan D. , Russell P.J.
Urol. Res.20:121-126(1992) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT BLADDER CANCER THR-59
26.

"Detection of point mutations in the Kirsten-ras oncogene provides evidence for the multicentricity of pancreatic carcinoma."
Motojima K. , Urano T. , Nagata Y. , Shiku H. , Tsurifune T. , Kanematsu T.
Ann. Surg.217:138-143(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS PANCREATIC CARCINOMA ASP-12 AND VAL-12
27.

"Clinicopathologic significance of the K-ras gene codon 12 point mutation in stomach cancer. An analysis of 140 cases."
Lee K.H. , Lee J.S. , Suh C. , Kim S.W. , Kim S.B. , Lee J.H. , Lee M.S. , Park M.Y. , Sun H.S. , Kim S.H.
Cancer75:2794-2801(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GASC SER-12 AND ASP-12
28.

"Biochemical characterization of a novel KRAS insertion mutation from a human leukemia."
Bollag G. , Adler F. , elMasry N. , McCabe P.C. , Conner E. Jr. , Thompson P. , McCormick F. , Shannon K.
J. Biol. Chem.271:32491-32494(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN AML;VARIANT GLY-10 INS;CHARACTERIZATION OF VARIANT GLY-10 INS
29.

"BRAF and KRAS mutations in stomach cancer."
Lee S.H. , Lee J.W. , Soung Y.H. , Kim H.S. , Park W.S. , Kim S.Y. , Lee J.H. , Park J.Y. , Cho Y.G. , Kim C.J. , Nam S.W. , Kim S.H. , Lee J.Y. , Yoo N.J.
Oncogene22:6942-6945(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS GASC ASN-5; VAL-12; ASP-13 AND THR-59
30.

"RAS pathway activation and an oncogenic RAS mutation in sporadic pilocytic astrocytoma."
Sharma M.K. , Zehnbauer B.A. , Watson M.A. , Gutmann D.H.
Neurology65:1335-1336(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT PYLOCYTIC ASTROCYTOMA ARG-13
31.

"Germline missense mutations affecting KRAS Isoform B are associated with a severe Noonan syndrome phenotype."
Carta C. , Pantaleoni F. , Bocchinfuso G. , Stella L. , Vasta I. , Sarkozy A. , Digilio C. , Palleschi A. , Pizzuti A. , Grammatico P. , Zampino G. , Dallapiccola B. , Gelb B.D. , Tartaglia M.
Am. J. Hum. Genet.79:129-135(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS NS3 GLY-152 (ISOSORM 2) AND VAL-153 (ISOFORM 2)
32.

"Distinct epidermal growth factor receptor and KRAS mutation patterns in non-small cell lung cancer patients with different tobacco exposure and clinicopathologic features."
Tam I.Y.S. , Chung L.P. , Suen W.S. , Wang E. , Wong M.C.M. , Ho K.K. , Lam W.K. , Chiu S.W. , Girard L. , Minna J.D. , Gazdar A.F. , Wong M.P.
Clin. Cancer Res.12:1647-1653(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS LUNG CARCINOMA CYS-12; ASP-12; SER-12; VAL-12 AND HIS-61
33.

"Germline KRAS and BRAF mutations in cardio-facio-cutaneous syndrome."
Niihori T. , Aoki Y. , Narumi Y. , Neri G. , Cave H. , Verloes A. , Okamoto N. , Hennekam R.C.M. , Gillessen-Kaesbach G. , Wieczorek D. , Kavamura M.I. , Kurosawa K. , Ohashi H. , Wilson L. , Heron D. , Bonneau D. , Corona G. , Kaname T. , more...
Nat. Genet.38:294-296(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT CFC2 ARG-60
34.

"Germline KRAS mutations cause Noonan syndrome."
Schubbert S. , Zenker M. , Rowe S.L. , Boell S. , Klein C. , Bollag G. , van der Burgt I. , Musante L. , Kalscheuer V. , Wehner L.-E. , Nguyen H. , West B. , Zhang K.Y.J. , Sistermans E. , Rauch A. , Niemeyer C.M. , Shannon K. , Kratz C.P.
Nat. Genet.38:331-336(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS NS3 ILE-14 AND ILE-58;VARIANT CFC2 ARG-34;CHARACTERIZATION OF VARIANTS NS3 ILE-14 AND ILE-58
35.

"The consensus coding sequences of human breast and colorectal cancers."
Sjoeblom T. , Jones S. , Wood L.D. , Parsons D.W. , Lin J. , Barber T.D. , Mandelker D. , Leary R.J. , Ptak J. , Silliman N. , Szabo S. , Buckhaults P. , Farrell C. , Meeh P. , Markowitz S.D. , Willis J. , Dawson D. , Willson J.K.V. , more...
Science314:268-274(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS [LARGE SCALE ANALYSIS] ALA-12; ASP-12; SER-12; VAL-12; ASP-13; ARG-61; ASN-117 AND THR-146
36.

"Further evidence of genetic heterogeneity in Costello syndrome: involvement of the KRAS gene."
Bertola D.R. , Pereira A.C. , Brasil A.S. , Albano L.M. , Kim C.A. , Krieger J.E.
J. Hum. Genet.52:521-526(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT NS3 GLU-5
37.

"Expansion of the genotypic and phenotypic spectrum in patients with KRAS germline mutations."
Zenker M. , Lehmann K. , Schulz A.L. , Barth H. , Hansmann D. , Koenig R. , Korinthenberg R. , Kreiss-Nachtsheim M. , Meinecke P. , Morlot S. , Mundlos S. , Quante A.S. , Raskin S. , Schnabel D. , Wehner L.E. , Kratz C.P. , Horn D. , Kutsche K.
J. Med. Genet.44:131-135(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS NS3 ILE-14; ARG-22; LEU-34; GLN-34; MET-36 AND VAL-153 (ISOFORM 2);VARIANT CFC2 GLU-22;VARIANT NS3/CFC2 ILE-156 (ISOFORM 2);VARIANTS ASN-5 AND LEU-156 (ISOFORM 2)
38.

"Craniosynostosis in patients with Noonan syndrome caused by germline KRAS mutations."
Kratz C.P. , Zampino G. , Kriek M. , Kant S.G. , Leoni C. , Pantaleoni F. , Oudesluys-Murphy A.M. , Di Rocco C. , Kloska S.P. , Tartaglia M. , Zenker M.
Am. J. Med. Genet. A149:1036-1040(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS NS3 ILE-58 AND SER-60
39.

"Germline KRAS mutations cause aberrant biochemical and physical properties leading to developmental disorders."
Gremer L. , Merbitz-Zahradnik T. , Dvorsky R. , Cirstea I.C. , Kratz C.P. , Zenker M. , Wittinghofer A. , Ahmadian M.R.
Hum. Mutat.32:33-43(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANTS NS3 ILE-14; ARG-22; LEU-34; ILE-58 AND VAL-153 (ISOFORM 2);CHARACTERIZATION OF VARIANTS CFC2 GLU-22; ARG-34 AND ARG-60;CHARACTERIZATION OF VARIANTS ASN-5 AND LEU-156 (ISOFORM 2)
40.

"Two novel germline KRAS mutations: expanding the molecular and clinical phenotype."
Stark Z. , Gillessen-Kaesbach G. , Ryan M.M. , Cirstea I.C. , Gremer L. , Ahmadian M.R. , Savarirayan R. , Zenker M.
Clin. Genet.81:590-594(2012) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS CFC2 HIS-71 AND GLU-147

Product Feedback Wall

* Email:
*Comments: