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Index > Protein center > RERE(Gene name) > Human
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  • RERE (Gene name),
  • Arginine-glutamic acid dipeptide repeats protein (Protein name ),  RERE_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    RERE(ARG;ARP;ATN1L;KIAA0458);
    Protein name:
    Arginine-glutamic acid dipeptide repeats protein;
    Alternative:
    Atrophin-1-related protein;Atrophin-1-like protein;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with HDAC1 (By similarity). Interacts with ATN1. Interaction with ATN1 is improved when the poly-Gln region of ATN1 is extended. Interacts with FAT1.
    Function:
    Plays a role as a transcriptional repressor during development. May play a role in the control of cell survival. Overexpression of RERE recruits BAX to the nucleus particularly to POD and triggers caspase-3 activation, leading to cell death.
    Subcellular Location:
    Nucleus Localized in nuclear bodies of variables size. Colocalized with PML and BAX in nuclear PODs.
    Protein Attributes:
    Sequence length:
    1566
    Sequence:
    50:
    MTADKDKDKD | KEKDRDRDRD | REREKRDKAR | ESENSRPRRS | CTLEGGAKNY | 
    100:
    AESDHSEDED | NDNNSATAEE | STKKNKKKPP | KKKSRYERTD | TGEITSYITE | 
    150:
    DDVVYRPGDC | VYIESRRPNT | PYFICSIQDF | KLVHNSQACC | RSPTPALCDP | 
    200:
    PACSLPVASQ | PPQHLSEAGR | GPVGSKRDHL | LMNVKWYYRQ | SEVPDSVYQH | 
    250:
    LVQDRHNEND | SGRELVITDP | VIKNRELFIS | DYVDTYHAAA | LRGKCNISHF | 
    300:
    SDIFAAREFK | ARVDSFFYIL | GYNPETRRLN | STQGEIRVGP | SHQAKLPDLQ | 
    350:
    PFPSPDGDTV | TQHEELVWMP | GVNDCDLLMY | LRAARSMAAF | AGMCDGGSTE | 
    400:
    DGCVAASRDD | TTLNALNTLH | ESGYDAGKAL | QRLVKKPVPK | LIEKCWTEDE | 
    450:
    VKRFVKGLRQ | YGKNFFRIRK | ELLPNKETGE | LITFYYYWKK | TPEAASSRAH | 
    500:
    RRHRRQAVFR | RIKTRTASTP | VNTPSRPPSS | EFLDLSSASE | DDFDSEDSEQ | 
    550:
    ELKGYACRHC | FTTTSKDWHH | GGRENILLCT | DCRIHFKKYG | ELPPIEKPVD | 
    600:
    PPPFMFKPVK | EEDDGLSGKH | SMRTRRSRGS | MSTLRSGRKK | QPASPDGRTS | 
    650:
    PINEDIRSSG | RNSPSAASTS | SNDSKAETVK | KSAKKVKEEA | SSPLKSNKRQ | 
    700:
    REKVASDTEE | ADRTSSKKTK | TQEISRPNSP | SEGEGESSDS | RSVNDEGSSD | 
    750:
    PKDIDQDNRS | TSPSIPSPQD | NESDSDSSAQ | QQMLQAQPPA | LQAPTGVTPA | 
    800:
    PSSAPPGTPQ | LPTPGPTPSA | TAVPPQGSPT | ASQAPNQPQA | PTAPVPHTHI | 
    850:
    QQAPALHPQR | PPSPHPPPHP | SPHPPLQPLT | GSAGQPSAPS | HAQPPLHGQG | 
    900:
    PPGPHSLQAG | PLLQHPGPPQ | PFGLPPQASQ | GQAPLGTSPA | AAYPHTSLQL | 
    950:
    PASQSALQSQ | QPPREQPLPP | APLAMPHIKP | PPTTPIPQLP | APQAHKHPPH | 
    1000:
    LSGPSPFSMN | ANLPPPPALK | PLSSLSTHHP | PSAHPPPLQL | MPQSQPLPSS | 
    1050:
    PAQPPGLTQS | QNLPPPPASH | PPTGLHQVAP | QPPFAQHPFV | PGGPPPITPP | 
    1100:
    TCPSTSTPPA | GPGTSAQPPC | SGAAASGGSI | AGGSSCPLPT | VQIKEEALDD | 
    1150:
    AEEPESPPPP | PRSPSPEPTV | VDTPSHASQS | ARFYKHLDRG | YNSCARTDLY | 
    1200:
    FMPLAGSKLA | KKREEAIEKA | KREAEQKARE | EREREKEKEK | ERERERERER | 
    1250:
    EAERAAKASS | SAHEGRLSDP | QLSGPGHMRP | SFEPPPTTIA | AVPPYIGPDT | 
    1300:
    PALRTLSEYA | RPHVMSPTNR | NHPFYMPLNP | TDPLLAYHMP | GLYNVDPTIR | 
    1350:
    ERELREREIR | EREIRERELR | ERMKPGFEVK | PPELDPLHPA | ANPMEHFARH | 
    1400:
    SALTIPPTAG | PHPFASFHPG | LNPLERERLA | LAGPQLRPEM | SYPDRLAAER | 
    1450:
    IHAERMASLT | SDPLARLQMF | NVTPHHHQHS | HIHSHLHLHQ | QDPLHQGSAG | 
    1500:
    PVHPLVDPLT | AGPHLARFPY | PPGTLPNPLL | GQPPHEHEML | RHPVFGTPYP | 
    1550:
    RDLPGAIPPP | MSAAHQLQAM | HAQSAELQRL | AMEQQWLHGH | PHMHGGHLPS | 
    1566:
    QEDYYSRLKK | EGDKQL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    SMR:
    String:
    MIM:
    KEGG:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human Arginine-glutamic acid dipeptide repeats protein
    ELISA Kit for Human Arginine-glutamic acid dipeptide repeats protein
    ELISA Kit for Human Arginine-glutamic acid dipeptide repeats protein
    CLIA Kit for Human Arginine-glutamic acid dipeptide repeats protein
    CLIA Kit for Human Arginine-glutamic acid dipeptide repeats protein
    CLIA Kit for Human Arginine-glutamic acid dipeptide repeats protein
    Polyclonal Antibody for Human Arginine-glutamic acid dipeptide repeats protein
    Polyclonal Antibody for Human Arginine-glutamic acid dipeptide repeats protein
    Polyclonal Antibody for Human Arginine-glutamic acid dipeptide repeats protein
    Monoclonal Antibody for Human Arginine-glutamic acid dipeptide repeats protein
    Monoclonal Antibody for Human Arginine-glutamic acid dipeptide repeats protein
    Monoclonal Antibody for Human Arginine-glutamic acid dipeptide repeats protein
    Protein for Human Arginine-glutamic acid dipeptide repeats protein
    Protein for Human Arginine-glutamic acid dipeptide repeats protein
    Protein for Human Arginine-glutamic acid dipeptide repeats protein

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Protein binding of a DRPLA family through arginine-glutamic acid dipeptide repeats is enhanced by extended polyglutamine."
      Yanagisawa H. , Bundo M. , Miyashita T. , Okamura-Oho Y. , Tadokoro K. , Tokunaga K. , Yamada M.
      Hum. Mol. Genet.9:1433-1442(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);INTERACTION WITH ATN1;SUBCELLULAR LOCATION;TISSUE SPECIFICITY
    2. 2.
      "Human RERE is localized to nuclear promyelocytic leukemia oncogenic domains and enhances apoptosis."
      Waerner T. , Gardellin P. , Pfizenmaier K. , Weith A. , Kraut N.
      Cell Growth Differ.12:201-210(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
    3. 3.
      "Cloning and localization of human atrophin-1 (DRPLA) related gene."
      Xia J.-H. , Liu C.-Y. , Ruan Q.-G. , Wang D.-A. , Deng H.-X.
      Submitted (1998-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORM 2)
    4. 4.
      "The DNA sequence and biological annotation of human chromosome 1."
      Gregory S.G. , Barlow K.F. , McLay K.E. , Kaul R. , Swarbreck D. , Dunham A. , Scott C.E. , Howe K.L. , Woodfine K. , Spencer C.C.A. , Jones M.C. , Gillson C. , Searle S. , Zhou Y. , Kokocinski F. , McDonald L. , Evans R. , Phillips K. , more...
      Nature441:315-321(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "Characterization of cDNA clones in size-fractionated cDNA libraries from human brain."
      Seki N. , Ohira M. , Nagase T. , Ishikawa K. , Miyajima N. , Nakajima D. , Nomura N. , Ohara O.
      DNA Res.4:345-349(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 15-1566 (ISOFORM 1)
      tissue: Brain.
    6. 6.
      "Identification and characterization of novel genes located at the t(1;15)(p36.2;q24) translocation breakpoint in the neuroblastoma cell line NGP."
      Amler L.C. , Bauer A. , Corvi R. , Dihlmann S. , Praml C. , Cavenee W.K. , Schwab M. , Hampton G.M.
      Genomics64:195-202(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 555-1566;TISSUE SPECIFICITY;CHROMOSOMAL TRANSLOCATION
    7. 7.
      "Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis."
      Cantin G.T. , Yi W. , Lu B. , Park S.K. , Xu T. , Lee J.-D. , Yates J.R. III
      J. Proteome Res.7:1346-1351(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-304 AND SER-1106;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-53; SER-56 AND SER-642;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    9. 9.
      "Atrophin proteins interact with the Fat1 cadherin and regulate migration and orientation in vascular smooth muscle cells."
      Hou R. , Sibinga N.E.
      J. Biol. Chem.284:6955-6965(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH FAT1
    10. 10.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-675 AND SER-679;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    11. 11.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-642;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    12. 12.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-53; SER-56; SER-642; SER-656; SER-675; SER-679 AND SER-1106;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    13. 13.
      "Solution structure of the SANT domain in arginine-glutamic acid dipeptide (RE) repeats."
      RIKEN structural genomics initiative (RSGI)
      Submitted (2007-10) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 392-446
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