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Index > Protein center > RBP4(Gene name) > Human
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  • RBP4 (Gene name),
  • Retinol-binding protein 4 (Protein name ),  RET4_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    RBP4(PRO2222);
    Protein name:
    Retinol-binding protein 4;
    Alternative:
    Plasma retinol-binding protein(PRBP;RBP);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin, this prevents its loss by filtration through the kidney glomeruli.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    201
    Sequence:
    50:
    MKWVWALLLL | AALGSGRAER | DCRVSSFRVK | ENFDKARFSG | TWYAMAKKDP | 
    100:
    EGLFLQDNIV | AEFSVDETGQ | MSATAKGRVR | LLNNWDVCAD | MVGTFTDTED | 
    150:
    PAKFKMKYWG | VASFLQKGND | DHWIVDTDYD | TYAVQYSCRL | LNLDGTCADS | 
    200:
    YSFVFSRDPN | GLPPEAQKIV | RQRQEELCLA | RQYRLIVHNG | YCDGRSERNL | 
    201:
    L
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    UniGene:
    SMR:
    KEGG:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Retinol-binding protein 4
    Cat.:
    E0929h
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    96T
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    ELISA Kit for Human Retinol-binding protein 4
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    E0929m
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    96T
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    ELISA Kit for Human Retinol-binding protein 4
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    E0929r
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    ELISA Kit for Human Retinol-binding protein 4
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    ELISA Kit for Human Retinol-binding protein 4
    Cat.:
    E0929b
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    96T
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    ELISA Kit for Human Retinol-binding protein 4
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    E0929p
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    MSDS:
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    96T
    ELISA Kit for Human Retinol-binding protein 4
    Cat.:
    E0929c
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    Packing:
    96T
    CLIA Kit for Human Retinol-binding protein 4
    Cat.:
    U0929m
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    Packing:
    96T
    CLIA Kit for Human Retinol-binding protein 4
    Cat.:
    U0929c
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Retinol-binding protein 4
    Cat.:
    U0929h
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Retinol-binding protein 4
    Cat.:
    U0929p
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Retinol-binding protein 4
    Cat.:
    U0929r
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    MSDS:
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    Packing:
    96T
    Range:
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    CLIA Kit for Human Retinol-binding protein 4
    MSDS:
    Please sign in first.
    CLIA Kit for Human Retinol-binding protein 4
    Cat.:
    U0929b
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Retinol-binding protein 4
    Cat.:
    P0929Rb-r
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Retinol-binding protein 4
    Polyclonal Antibody for Human Retinol-binding protein 4
    Polyclonal Antibody for Human Retinol-binding protein 4
    Polyclonal Antibody for Human Retinol-binding protein 4
    Cat.:
    P0929Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Retinol-binding protein 4
    Polyclonal Antibody for Human Retinol-binding protein 4
    Cat.:
    P0929Rb-m
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    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Retinol-binding protein 4
    Monoclonal Antibody for Human Retinol-binding protein 4
    Monoclonal Antibody for Human Retinol-binding protein 4
    Monoclonal Antibody for Human Retinol-binding protein 4
    Monoclonal Antibody for Human Retinol-binding protein 4
    Monoclonal Antibody for Human Retinol-binding protein 4
    Monoclonal Antibody for Human Retinol-binding protein 4
    Protein for Human Retinol-binding protein 4
    Protein for Human Retinol-binding protein 4
    Protein for Human Retinol-binding protein 4
    Protein for Human Retinol-binding protein 4
    Protein for Human Retinol-binding protein 4
    Protein for Human Retinol-binding protein 4
    Protein for Human Retinol-binding protein 4

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Cloning and sequencing of a full length cDNA coding for human retinol-binding protein."
      Colantuoni V. , Romano V. , Bensi G. , Santoro C. , Costanzo F. , Raugei G. , Cortese R.
      Nucleic Acids Res.11:7769-7776(1983) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The DNA sequence and comparative analysis of human chromosome 10."
      Deloukas P. , Earthrowl M.E. , Grafham D.V. , Rubenfield M. , French L. , Steward C.A. , Sims S.K. , Jones M.C. , Searle S. , Scott C. , Howe K. , Hunt S.E. , Andrews T.D. , Gilbert J.G.R. , Swarbreck D. , Ashurst J.L. , Taylor A. , Battles J. , more...
      Nature429:375-381(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Liver.
    5. 5.
      "Structure and cell-specific expression of a cloned human retinol binding protein gene: the 5'-flanking region contains hepatoma specific transcriptional signals."
      D'Onofrio C. , Colantuoni V. , Cortese R.
      EMBO J.4:1981-1989(1985) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-189
    6. 6.
      "The complete amino acid sequence of human serum retinol-binding protein."
      Rask L. , Anundi H. , Fohlman J. , Peterson P.A.
      Ups. J. Med. Sci.92:115-146(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 19-201;DISULFIDE BONDS
    7. 7.
      "Structural and functional studies of vitamin A-binding proteins."
      Rask L. , Anundi H. , Boehme J. , Eriksson U. , Ronne H. , Sege K. , Peterson P.A.
      Ann. N. Y. Acad. Sci.359:79-90(1981) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 19-201
    8. 8.
      "The primary structure of the human retinol-binding protein."
      Rask L. , Anundi H. , Peterson P.A.
      FEBS Lett.104:55-58(1979) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 19-183
    9. 9.
      "Functional prediction of the coding sequences of 79 new genes deduced by analysis of cDNA clones from human fetal liver."
      Zhang C. , Yu Y. , Zhang S. , Wei H. , Zhang Y. , Zhou G. , Bi J. , Liu M. , He F.
      Submitted (1999-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 18-201
      tissue: Fetal liver.
    10. 10.
      "Characterization of two post-translationally processed forms of human serum retinol-binding protein: altered ratios in chronic renal failure."
      Jaconi S. , Rose K. , Hughes G.J. , Saurat J.-H. , Siegenthaler G.
      J. Lipid Res.36:1247-1253(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PARTIAL PROTEIN SEQUENCE;MASS SPECTROMETRY
    11. 11.
      "Comparative phenotypic analyses of human plasma and urinary retinol binding protein using mass spectrometric immunoassay."
      Kiernan U.A. , Tubbs K.A. , Nedelkov D. , Niederkofler E.E. , Nelson R.W.
      Biochem. Biophys. Res. Commun.297:401-405(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MASS SPECTROMETRY
    12. 12.
      "Comparative urine protein phenotyping using mass spectrometric immunoassay."
      Kiernan U.A. , Tubbs K.A. , Nedelkov D. , Niederkofler E.E. , McConnell E. , Nelson R.W.
      J. Proteome Res.2:191-197(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY
    13. 13.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    14. 14.
      "Exome analysis identified a novel mutation in the RBP4 gene in a consanguineous pedigree with retinal dystrophy and developmental abnormalities."
      Cukras C. , Gaasterland T. , Lee P. , Gudiseva H.V. , Chavali V.R. , Pullakhandam R. , Maranhao B. , Edsall L. , Soares S. , Reddy G.B. , Sieving P.A. , Ayyagari R.
      PLoS ONE7:E50205-E50205(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INVOLVEMENT IN RDCCAS
    15. 15.
      "The three-dimensional structure of retinol-binding protein."
      Newcomer M.E. , Jones T.A. , Aqvist J. , Sundelin J. , Eriksson U. , Rask L. , Peterson P.A.
      EMBO J.3:1451-1454(1984) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.1 ANGSTROMS)
    16. 16.
      "Crystallographic refinement of human serum retinol binding protein at 2-A resolution."
      Cowan S.W. , Newcomer M.E. , Jones T.A.
      Proteins8:44-61(1990) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS)
    17. 17.
      "Three-dimensional structure and active site of three hydrophobic molecule-binding proteins with significant amino acid sequence similarity."
      Monaco H.L. , Zanotti G.
      Biopolymers32:457-465(1992) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: COMPARISON OF X-RAY STRUCTURES
    18. 18.
      "The structure of human retinol-binding protein (RBP) with its carrier protein transthyretin reveals an interaction with the carboxy terminus of RBP."
      Naylor H.M. , Newcomer M.E.
      Biochemistry38:2647-2653(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (3.2 ANGSTROMS) OF COMPLEX WITH TTR
    19. 19.
      "Phenotype in retinol deficiency due to a hereditary defect in retinol binding protein synthesis."
      Seeliger M.W. , Biesalski H.K. , Wissinger B. , Gollnick H. , Gielen S. , Frank J. , Beck S.C. , Zrenner E.
      Invest. Ophthalmol. Vis. Sci.40:3-11(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANTS RDCCAS ASN-59 AND ASP-93
    20. 20.
      "Biochemical but not clinical vitamin A deficiency results from mutations in the gene for retinol binding protein."
      Biesalski H.K. , Frank J. , Beck S.C. , Heinrich F. , Illek B. , Reifen R. , Gollnick H. , Seeliger M.W. , Wissinger B. , Zrenner E.
      Am. J. Clin. Nutr.69:931-936(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: CHARACTERIZATION OF VARIANTS RDCCAS ASN-59 AND ASP-93
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