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Index > Protein center > RNASE7(Gene name) > Human
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  • RNASE7 (Gene name),
  • Ribonuclease 7 (Protein name ),  RNAS7_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    RNASE7(UNQ2516/PRO6006);
    Protein name:
    Ribonuclease 7(RNase 7);
    Alternative:
    Skin-derived antimicrobial protein 2(SAP-2);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    156
    Sequence:
    50:
    MAPARAGFCP | LLLLLLLGLW | VAEIPVSAKP | KGMTSSQWFK | IQHMQPSPQA | 
    100:
    CNSAMKNINK | HTKRCKDLNT | FLHEPFSSVA | ATCQTPKIAC | KNGDKNCHQS | 
    150:
    HGAVSLTMCK | LTSGKHPNCR | YKEKRQNKSY | VVACKPPQKK | DSQQFHLVPV | 
    156:
    HLDRVL
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    SMR:
    KEGG:
    UniGene:
    MIM:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Human RNase 7
    Cat.:
    E10076h
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human RNase 7
    Cat.:
    U10076h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human RNase 7
    Cat.:
    P10076Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human RNase 7
    Protein for Human RNase 7

    R&D Technical Data
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    Precision
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin."
      Harder J. , Schroeder J.M.
      J. Biol. Chem.277:46779-46784(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY;VARIANTS PRO-103 AND TYR-116
    2. 2.
      "Human RNase 7: a new cationic ribonuclease of the RNase A superfamily."
      Zhang J. , Dyer K.D. , Rosenberg H.F.
      Nucleic Acids Res.31:602-607(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;TISSUE SPECIFICITY;VARIANTS PRO-103 AND TYR-116
      tissue: Kidney.
    3. 3.
      "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
      Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
      Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS PRO-103 AND TYR-116
    4. 4.
      "The DNA sequence and analysis of human chromosome 14."
      Heilig R. , Eckenberg R. , Petit J.-L. , Fonknechten N. , Da Silva C. , Cattolico L. , Levy M. , Barbe V. , De Berardinis V. , Ureta-Vidal A. , Pelletier E. , Vico V. , Anthouard V. , Rowen L. , Madan A. , Qin S. , Sun H. , Du H. , more...
      Nature421:601-607(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANTS PRO-103 AND TYR-116
    6. 6.
      Harder J. , Bartels J. , Christophers E. , Schroeder J.M.
      Submitted (1997-03) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PRELIMINARY PROTEIN SEQUENCE OF 30-70
      tissue: Keratinocyte.
    7. 7.
      "The flexible and clustered lysine residues of human ribonuclease 7 are critical for membrane permeability and antimicrobial activity."
      Huang Y.-C. , Lin Y.-M. , Chang T.-W. , Wu S.-J. , Lee Y.-S. , Chang M.D.-S. , Chen C. , Wu S.-H. , Liao Y.-D.
      J. Biol. Chem.282:4626-4633(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 29-156;DISULFIDE BONDS;FUNCTION
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