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Index > Protein center > RND1(Gene name) > Human
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  • RND1 (Gene name),
  • Rho-related GTP-binding protein Rho6 (Protein name ),  RND1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    RND1(RHO6);
    Protein name:
    Rho-related GTP-binding protein Rho6;
    Alternative:
    Rnd1;Rho family GTPase 1;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Binds GRB7 and PLXNB1. Interacts with UBXD5. Interacts with PLXNA2.
    Function:
    Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.
    Subcellular Location:
    Cell membrane Lipid-anchor Cytoplasmic side Cytoplasm cytoskeleton
    Protein Attributes:
    Sequence length:
    232
    Sequence:
    50:
    MKERRAPQPV | VARCKLVLVG | DVQCGKTAML | QVLAKDCYPE | TYVPTVFENY | 
    100:
    TACLETEEQR | VELSLWDTSG | SPYYDNVRPL | CYSDSDAVLL | CFDISRPETV | 
    150:
    DSALKKWRTE | ILDYCPSTRV | LLIGCKTDLR | TDLSTLMELS | HQKQAPISYE | 
    200:
    QGCAIAKQLG | AEIYLEGSAF | TSEKSIHSIF | RTASMLCLNK | PSPLPQKSPV | 
    232:
    RSLSKRLLHL | PSRSELISST | FKKEKAKSCS | IM
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
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    Related Databases
    Pfam:
    UniGene:
    SMR:
    KEGG:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human Rho-related GTP-binding protein Rho6
    Cat.:
    E1788h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Human Rho-related GTP-binding protein Rho6
    Cat.:
    E1788b
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    MSDS:
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    Packing:
    96T
    ELISA Kit for Human Rho-related GTP-binding protein Rho6
    Cat.:
    E1788m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Rho-related GTP-binding protein Rho6
    Cat.:
    U1788b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Human Rho-related GTP-binding protein Rho6
    Cat.:
    U1788h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Rho-related GTP-binding protein Rho6
    Cat.:
    U1788m
    Price:
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    MSDS:
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    Packing:
    96T
    Polyclonal Antibody for Human Rho-related GTP-binding protein Rho6
    Cat.:
    P1788Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Rho-related GTP-binding protein Rho6
    Polyclonal Antibody for Human Rho-related GTP-binding protein Rho6
    Cat.:
    P1788Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Rho-related GTP-binding protein Rho6
    Monoclonal Antibody for Human Rho-related GTP-binding protein Rho6
    Monoclonal Antibody for Human Rho-related GTP-binding protein Rho6
    Protein for Human Rho-related GTP-binding protein Rho6
    Protein for Human Rho-related GTP-binding protein Rho6
    Protein for Human Rho-related GTP-binding protein Rho6

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion."
      Nobes C.D. , Lauritzen I. , Mattei M.-G. , Paris S. , Hall A. , Chardin P.
      J. Cell Biol.141:187-197(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "Human Rnd1 in carcinogenesis."
      Tanaka S. , Sugimachi K.
      Submitted (2000-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
      Puhl H.L. III , Ikeda S.R. , Aronstam R.S.
      Submitted (2002-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    7. 7.
      "Rnd1, a novel rho family GTPase, induces the formation of neuritic processes in PC12 cells."
      Aoki J. , Katoh H. , Mori K. , Negishi M.
      Biochem. Biophys. Res. Commun.278:604-608(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    8. 8.
      "Interaction of the Grb7 adapter protein with Rnd1, a new member of the Rho family."
      Vayssiere B. , Zalcman G. , Mahe Y. , Mirey G. , Ligensa T. , Weidner K.M. , Chardin P. , Camonis J.
      FEBS Lett.467:91-96(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GRB7
    9. 9.
      "Socius is a novel Rnd GTPase-interacting protein involved in disassembly of actin stress fibers."
      Katoh H. , Harada A. , Mori K. , Negishi M.
      Mol. Cell. Biol.22:2952-2964(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH UBXD5;MUTAGENESIS OF THR-27 AND THR-45;SUBCELLULAR LOCATION
    10. 10.
      "Direct interaction of Rnd1 with Plexin-B1 regulates PDZ-RhoGEF-mediated Rho activation by Plexin-B1 and induces cell contraction in COS-7 cells."
      Oinuma I. , Katoh H. , Harada A. , Negishi M.
      J. Biol. Chem.278:25671-25677(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PLXNB1
    11. 11.
      "Structure and function of the intracellular region of the plexin-B1 transmembrane receptor."
      Tong Y. , Hota P.K. , Penachioni J.Y. , Hamaneh M.B. , Kim S. , Alviani R.S. , Shen L. , He H. , Tempel W. , Tamagnone L. , Park H.W. , Buck M.
      J. Biol. Chem.284:35962-35972(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 5-200 IN COMPLEX WITH GDP AND PLXNB1
    12. 12.
      "Crystal structure of plexin A2 RBD in complex with RND1."
      Structural genomics consortium (SGC)
      Submitted (2011-01) to the PDB data bank
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (1.97 ANGSTROMS) OF 5-200 IN COMPLEX WITH PLXNA2
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