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Index > Protein center > Slc12a7(Gene name) > Rat
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  • Slc12a7 (Gene name),
  • Solute carrier family 12 member 7 (Protein name ),  S12A7_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Slc12a7(Kcc4);
    Protein name:
    Solute carrier family 12 member 7;
    Alternative:
    K-Cl cotransporter 4;Electroneutral potassium-chloride cotransporter 4;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Homomultimer and heteromultimer with other K-Cl cotransporters.
    Function:
    Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters' cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    1083
    Sequence:
    50:
    MPTNFTVVPV | EARADGAGDE | AAERTEEPGS | PESADPACPT | PGDGNPRENS | 
    100:
    PFINNVEVER | ESYFEGKNMA | LFEEEMDSNP | MVSSLLNKLA | NYTNLSQGVV | 
    150:
    EHEEDEDSRR | REIKAPRMGT | FIGVYLPCLQ | NILGVILFLR | LTWIVGAAGV | 
    200:
    LESFLIVAMC | CTCTMLTAIS | MSAIATNGVV | PAGGSYYMIS | RSLGPEFGGA | 
    250:
    VGLCFYLGTT | FAGAMYILGT | IEIFLTYISP | SAAIFQAETA | DGEAAALLNN | 
    300:
    MRVYGSCALA | LMAVVVFVGV | KYVNKLALVF | LACVVLSILA | IYAGVIKTAF | 
    350:
    APPDIPVCLL | GNRTLANRNF | DTCAKMQVVS | NGTVTTALWR | LFCNGSSLGA | 
    400:
    SCDEYFVQNN | VTEIQGIPGV | ASGVFLDNLW | STYSDKGAFV | EKKGVSSVPV | 
    450:
    SEESRPGGLP | YVLTDIMTYF | TMLVGIYFPS | VTGIMAGSNR | SGDLKDAQKS | 
    500:
    IPTGTILAIV | TTSFIYLSCI | VLFGACIEGV | VLRDKFGEAL | QGNLVIGMLA | 
    550:
    WPSPWVIVIG | SFFSTCGAGL | QSLTGAPRLL | QAIARDGIIP | FLQVFGHGKA | 
    600:
    NGEPTWALLL | TALICETGIL | IASLDSVAPI | LSMFFLMCYM | FVNLACAVQT | 
    650:
    LLRTPNWRPR | FKFYHWTLSF | LGMSLCLALM | FICSWYYALF | AMLIAGCIYK | 
    700:
    YIEYRGAEKE | WGDGIRGLSL | NAARYALLRV | EHGPPHTKNW | RPQVLVMLNL | 
    750:
    DSEQCVKHPR | LLSFTSQLKA | GKGLTIVGSV | LEGTYLDKHV | EAQRAEENIR | 
    800:
    SLMSAEKMKG | FCQLVVSSNL | RDGASHLIQS | AGLGGMKHNT | VLMAWPEAWK | 
    850:
    QADNPFSWKN | FVDTVRDTTA | AHQALLVAKN | IDLFPQNQER | FSDGNIDVWW | 
    900:
    IVHDGGMLML | LPFLLRQHKV | WRKCRMRIFT | VAQVDDNSIQ | MKKDLQMFLY | 
    950:
    HLRISAEVEV | VEMVENDISA | FTYEKTLMME | QRSQMLKQMQ | LSKNEREREA | 
    1000:
    QLIHDRNTAS | HTVATARTEA | PPTPDKVQMT | WTKEKLIAEK | HRNKDTGTSG | 
    1050:
    FKDLFSLKPD | QSNVRRMHTA | VKLNGVVLNK | SQDAQLVLLN | MPGPPKSRQG | 
    1083:
    DENYMEFLEV | LTEGLNRVLL | VRGGGREVIT | IYS
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Solute carrier family 12 member 7
    ELISA Kit for Rat Solute carrier family 12 member 7
    ELISA Kit for Rat Solute carrier family 12 member 7
    ELISA Kit for Rat Solute carrier family 12 member 7
    CLIA Kit for Rat Solute carrier family 12 member 7
    CLIA Kit for Rat Solute carrier family 12 member 7
    CLIA Kit for Rat Solute carrier family 12 member 7
    CLIA Kit for Rat Solute carrier family 12 member 7
    Polyclonal Antibody for Rat Solute carrier family 12 member 7
    Polyclonal Antibody for Rat Solute carrier family 12 member 7
    Polyclonal Antibody for Rat Solute carrier family 12 member 7
    Polyclonal Antibody for Rat Solute carrier family 12 member 7
    Monoclonal Antibody for Rat Solute carrier family 12 member 7
    Monoclonal Antibody for Rat Solute carrier family 12 member 7
    Monoclonal Antibody for Rat Solute carrier family 12 member 7
    Monoclonal Antibody for Rat Solute carrier family 12 member 7
    Protein for Rat Solute carrier family 12 member 7
    Protein for Rat Solute carrier family 12 member 7
    Protein for Rat Solute carrier family 12 member 7
    Protein for Rat Solute carrier family 12 member 7

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    Precision
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    Linearity
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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-213
      tissue: Ovary.
    3. 3.
      "Rattus norvegicus K-CL cotransporter KCC4."
      Le Rouzic P. , Stanley S.J. , Luckman S.M.
      Submitted (2003-10) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 26-159
      strain: Sprague-Dawley.
      tissue: Pancreas.
    4. 4.
      "Aldosterone up regulates K+-Cl- cotransporter expression and activity in arterial tissue."
      Lopez N.C. , Michea L.
      Submitted (2003-09) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 80-105 AND 113-129
      strain: Sprague-Dawley.
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
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