Protein name:
SEC14-like protein 2 ;
Alternative:
Alpha-tocopherol-associated protein (TAP) ;
Organism:
Mouse (Mus musculus).
General Annotation
Function:
Carrier protein. Binds to some hydrophobic molecules and promotes their transfer between the different cellular sites. Binds with high affinity to alpha-tocopherol. Also binds with a weaker affinity to other tocopherols and to tocotrienols. May have a transcriptional activatory activity via its association with alpha-tocopherol. Probably recognizes and binds some squalene structure, suggesting that it may regulate cholesterol biosynthesis by increasing the transfer of squalene to a metabolic active pool in the cell.
Subcellular Location:
Cytoplasm
Nucleus
Cytoplasmic in absence of alpha-tocopherol, and nuclear in presence of alpha-tocopherol.
Protein Attributes:
50:
MSGRVGDLSP | KQEEALAKFR | ENVQDVLPTL | PNPDDYFLLR | WLRARSFDLQ |
100:
KSEAMLRKHV | EFRKQKDIDK | IISWQPPEVI | QQYLSGGRCG | YDLDGCPVWY |
150:
DIIGPLDAKG | LLFSASKQDL | LRTKMRDCEL | LLQECIQQTT | KLGKKIETIT |
200:
MIYDCEGLGL | KHLWKPAVEA | YGEFLTMFEE | NYPETLKRLF | VVKAPKLFPV |
250:
AYNLIKPFLS | EDTRRKIMVL | GANWKEVLLK | HISPDQLPVE | YGGTMTDPDG |
300:
NPKCKSKINY | GGDIPKQYYV | RDQVKQQYEH | TVQVSRGSSH | QVEYEILFPG |
350:
CVLRWQFMSE | GSDVGFGIFL | KTKMGERQRA | GEMTEVLPNQ | RYNSHMVPED |
400:
GTLTCSEPGI | YVLRFDNTYS | FIHAKKVSFT | VEVLLPDKAA | EEKMNQQGAD |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Bovine
Human
Rat
Mouse
ELISA Kit for Mouse SEC14-like protein 2
ELISA Kit for Mouse SEC14-like protein 2
ELISA Kit for Mouse SEC14-like protein 2
ELISA Kit for Mouse SEC14-like protein 2
CLIA Kit for Mouse SEC14-like protein 2
CLIA Kit for Mouse SEC14-like protein 2
CLIA Kit for Mouse SEC14-like protein 2
CLIA Kit for Mouse SEC14-like protein 2
Polyclonal Antibody for Mouse SEC14-like protein 2
Polyclonal Antibody for Mouse SEC14-like protein 2
Polyclonal Antibody for Mouse SEC14-like protein 2
Polyclonal Antibody for Mouse SEC14-like protein 2
Monoclonal Antibody for Mouse SEC14-like protein 2
Monoclonal Antibody for Mouse SEC14-like protein 2
Monoclonal Antibody for Mouse SEC14-like protein 2
Monoclonal Antibody for Mouse SEC14-like protein 2
Protein for Mouse SEC14-like protein 2
Protein for Mouse SEC14-like protein 2
Protein for Mouse SEC14-like protein 2
Protein for Mouse SEC14-like protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
2.
"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J.
,
Chen Y.
,
Tishkoff D.X.
,
Peng C.
,
Tan M.
,
Dai L.
,
Xie Z.
,
Zhang Y.
,
Zwaans B.M.
,
Skinner M.E.
,
Lombard D.B.
,
Zhao Y.
Mol. Cell50:919-930(2013)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUCCINYLATION [LARGE SCALE ANALYSIS] AT LYS-11; LYS-51; LYS-253; LYS-257 AND LYS-393;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue :
Liver .