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Index > Protein center > S1PR4(Gene name) > Human
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  • S1PR4 (Gene name),
  • Sphingosine 1-phosphate receptor 4 (Protein name ),  S1PR4_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    S1PR4(EDG6);
    Protein name:
    Sphingosine 1-phosphate receptor 4(S1P receptor 4;S1P4);
    Alternative:
    Endothelial differentiation G-protein coupled receptor 6;Sphingosine 1-phosphate receptor Edg-6(S1P receptor Edg-6);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. May be involved in cell migration processes that are specific for lymphocytes.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    384
    Sequence:
    50:
    MNATGTPVAP | ESCQQLAAGG | HSRLIVLHYN | HSGRLAGRGG | PEDGGLGALR | 
    100:
    GLSVAASCLV | VLENLLVLAA | ITSHMRSRRW | VYYCLVNITL | SDLLTGAAYL | 
    150:
    ANVLLSGART | FRLAPAQWFL | REGLLFTALA | ASTFSLLFTA | GERFATMVRP | 
    200:
    VAESGATKTS | RVYGFIGLCW | LLAALLGMLP | LLGWNCLCAF | DRCSSLLPLY | 
    250:
    SKRYILFCLV | IFAGVLATIM | GLYGAIFRLV | QASGQKAPRP | AARRKARRLL | 
    300:
    KTVLMILLAF | LVCWGPLFGL | LLADVFGSNL | WAQEYLRGMD | WILALAVLNS | 
    350:
    AVNPIIYSFR | SREVCRAVLS | FLCCGCLRLG | MRGPGDCLAR | AVEAHSGAST | 
    384:
    TDSSLRPRDS | FRGSRSLSFR | MREPLSSISS | VRSI
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    KEGG:
    SMR:
    String:
    Pfam:
    MIM:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Human S1P receptor 4
    Cat.:
    E0327m
    Price:
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    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human S1P receptor 4
    Cat.:
    E0327h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human S1P receptor 4
    Cat.:
    U0327h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human S1P receptor 4
    Cat.:
    U0327m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human S1P receptor 4
    Cat.:
    P0327Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human S1P receptor 4
    Cat.:
    P0327Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human S1P receptor 4
    Monoclonal Antibody for Human S1P receptor 4
    Protein for Human S1P receptor 4
    Protein for Human S1P receptor 4

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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "EDG6, a novel G protein-coupled receptor related to receptors for bioactive lysophospholipids, is specifically expressed in lymphoid tissue."
      Graeler M.H. , Bernhardt G. , Lipp M.
      Genomics53:164-169(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Dendritic cell.
    2. 2.
      "cDNA clones of human proteins involved in signal transduction sequenced by the Guthrie cDNA resource center (www.cdna.org)."
      Kopatz S.A. , Aronstam R.S. , Sharma S.V.
      Submitted (2003-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Blood.
    5. 5.
      "Edg-6 as a putative sphingosine 1-phosphate receptor coupling to Ca(2+) signaling pathway."
      Yamazaki Y. , Kon J. , Sato K. , Tomura H. , Sato M. , Yoneya T. , Okazaki H. , Okajima F. , Ohta H.
      Biochem. Biophys. Res. Commun.268:583-589(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    6. 6.
      "Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6."
      Van Brocklyn J.R. , Graeler M.H. , Bernhardt G. , Hobson J.P. , Lipp M. , Spiegel S.
      Blood95:2624-2629(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    7. 7.
      "Peptide design and structural characterization of a GPCR loop mimetic."
      Pham T.-C.T. , Kriwacki R.W. , Parrill A.L.
      Biopolymers86:298-310(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: STRUCTURE BY NMR OF 105-122
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