Gene name:
Slc22a12 (Urat1) ;
Protein name:
Solute carrier family 22 member 12 ;
Alternative:
Urate anion exchanger 1 ;Renal-specific transporter (RST) ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with PDZK1.
Function:
Required for efficient urate re-absorption in the kidney. Regulates blood urate levels. Mediates saturable urate uptake by facilitating the exchange of urate against organic anions or chloride ions.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Detected in the luminal membrane of the epithelium of renal proximal tubules.
Protein Attributes:
50:
MAFPELLDRV | GGLGRFQLFQ | TVALVTPILW | VTTQNMLENF | SAAVPHHRCW |
100:
VPLLDNSTSQ | ASIPGDLGPD | VLLAVSIPPG | PDQQPHQCLR | FRQPQWQLTE |
150:
SNATATNWSD | AATEPCEDGW | VYDHSTFRST | IVTTWDLVCN | SQALRPMAQS |
200:
IFLAGILVGA | AVCGHASDRF | GRRRVLTWSY | LLVSVSGTAA | AFMPTFPLYC |
250:
LFRFLLASAV | AGVMMNTASL | LMEWTSAQGS | PLVMTLNALG | FSFGQVLTGS |
300:
VAYGVRSWRM | LQLAVSAPFF | LFFVYSWWLP | ESARWLITVG | KLDQGLQELQ |
350:
RVAAVNRRKA | EGDTLTMEVL | RSAMEEEPSR | DKAGASLGTL | LHTPGLRHRT |
400:
IISMLCWFAF | GFTFYGLALD | LQALGSNIFL | LQALIGIVDF | PVKTGSLLLI |
450:
SRLGRRFCQV | SFLVLPGLCI | LSNILVPHGM | GVLRSALAVL | GLGCLGGAFT |
500:
CITIFSSELF | PTVIRMTAVG | LCQVAARGGA | MLGPLVRLLG | VYGSWMPLLV |
550:
YGVVPVLSGL | AALLLPETKN | LPLPDTIQDI | QKQSVKKVTH | DTPDGSILMS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
ELISA Kit for Mouse Solute carrier family 22 member 12
ELISA Kit for Mouse Solute carrier family 22 member 12
ELISA Kit for Mouse Solute carrier family 22 member 12
CLIA Kit for Mouse Solute carrier family 22 member 12
CLIA Kit for Mouse Solute carrier family 22 member 12
CLIA Kit for Mouse Solute carrier family 22 member 12
Polyclonal Antibody for Mouse Solute carrier family 22 member 12
Polyclonal Antibody for Mouse Solute carrier family 22 member 12
Polyclonal Antibody for Mouse Solute carrier family 22 member 12
Monoclonal Antibody for Mouse Solute carrier family 22 member 12
Monoclonal Antibody for Mouse Solute carrier family 22 member 12
Monoclonal Antibody for Mouse Solute carrier family 22 member 12
Protein for Mouse Solute carrier family 22 member 12
Protein for Mouse Solute carrier family 22 member 12
Protein for Mouse Solute carrier family 22 member 12
R&D Technical Data
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Precision
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Recovery
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Linearity
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References
1.
"Kidney-specific expression of a novel mouse organic cation transporter-like protein."
Mori K.
,
Ogawa Y.
,
Ebihara K.
,
Aoki T.
,
Tamura N.
,
Sugawara A.
,
Kuwahara T.
,
Ozaki S.
,
Mukoyama M.
,
Tashiro K.
,
Tanaka I.
,
Nakao K.
FEBS Lett.417:371-374(1997)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY
tissue :
Kidney .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
FVB/N .
tissue :
Kidney .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;GLYCOSYLATION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION