Slc4a4 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comSlc4a4 ELISA Kit for Rat(Rattus norvegicus)

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Index > Protein center > Slc4a4(Gene name) > Rat

Slc4a4 (Gene name),

Electrogenic sodium bicarbonate cotransporter 1 (Protein name ), S4A4_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Slc4a4(Nbc;Nbc1;Nbce1;Rnbc1);

Protein name:

Electrogenic sodium bicarbonate cotransporter 1(Sodium bicarbonate cotransporter);

Alternative:

Na(+)/HCO3(-) cotransporter;NBC-like protein;Solute carrier family 4 member 4;

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Interacts with CA2/carbonic anhydrase 2 and CA4/carbonic anhydrase 4 which may regulate transporter activity.

Function:

Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH.

Subcellular Location:

Basolateral cell membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

1079

Sequence:

50:

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950:

1000:

1050:

1079:

ITEQQPFLSD | NKPLDRERSS | TFLERHTSC

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

Pfam:

PF07565

UniGene:

Rn.11114

String:

Q9JI66

KEGG:

rno:84484

Uniprot:

Q9JI66

FOR

ELISA Kit for Rat Sodium bicarbonate cotransporter

CLIA Kit for Rat Sodium bicarbonate cotransporter

Polyclonal Antibody for Rat Sodium bicarbonate cotransporter

Monoclonal Antibody for Rat Sodium bicarbonate cotransporter

Protein for Rat Sodium bicarbonate cotransporter

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Cloning and functional expression of rNBC, an electrogenic Na(+)-HCO3-cotransporter from rat kidney."
Romero M.F. , Fong P. , Berger U.V. , Hediger M.A. , Boron W.F.
Am. J. Physiol.274:F425-F432(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);FUNCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
tissue: Kidney cortex.
2.

"Cloning, renal distribution, and regulation of the rat Na+-HCO3-cotransporter."
Burnham C.E. , Flagella M. , Wang Z. , Amlal H. , Shull G.E. , Soleimani M.
Am. J. Physiol.274:F1119-F1126(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2);TISSUE SPECIFICITY;INDUCTION
strain: Sprague-Dawley.
tissue: Kidney.
3.

"An electrogenic Na(+)-HCO3(-) cotransporter (NBC) with a novel COOH-terminus, cloned from rat brain."
Bevensee M.O. , Schmitt B.M. , Choi I. , Romero M.F. , Boron W.F.
Am. J. Physiol.278:C1200-C1211(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 3);FUNCTION;REGULATION;TISSUE SPECIFICITY
tissue: Brain.
4.

"The electrogenic sodium bicarbonate cotransporter: developmental expression in rat brain and possible role in acid vulnerability."
Giffard R.G. , Papadopoulos M.C. , van Hooft J.A. , Xu L. , Giuffrida R. , Monyer H.
J. Neurosci.20:1001-1008(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
tissue: Brain.
5.

"Immunolocalization of electrogenic sodium-bicarbonate cotransporters pNBC1 and kNBC1 in the rat eye."
Bok D. , Schibler M.J. , Pushkin A. , Sassani P. , Abuladze N. , Naser Z. , Kurtz I.
Am. J. Physiol.281:F920-F935(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
6.

"Coordinated down-regulation of NBC-1 and NHE-3 in sodium and bicarbonate loading."
Amlal H. , Chen Q. , Greeley T. , Pavelic L. , Soleimani M.
Kidney Int.60:1824-1836(2001) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
7.

"Localization of Na+-HCO-3 cotransporter (NBC-1) variants in rat and human pancreas."
Satoh H. , Moriyama N. , Hara C. , Yamada H. , Horita S. , Kunimi M. , Tsukamoto K. , Iso-O N. , Inatomi J. , Kawakami H. , Kudo A. , Endou H. , Igarashi T. , Goto A. , Fujita T. , Seki G.
Am. J. Physiol.284:C729-C737(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
8.

"Role of glycosylation in the renal electrogenic Na+-HCO3-cotransporter (NBCe1)."
Choi I. , Hu L. , Rojas J.D. , Schmitt B.M. , Boron W.F.
Am. J. Physiol.284:F1199-F1206(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: MUTAGENESIS OF ASN-243; ASN-252; ASN-541; ASN-636; ASN-641 AND ASN-661;GLYCOSYLATION AT ASN-641 AND ASN-661
9.

"Expression of Na+/HCO3- co-transporter proteins (NBCs) in rat and human skeletal muscle."
Kristensen J.M. , Kristensen M. , Juel C.
Acta Physiol. Scand.182:69-76(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
10.

"Inhibition of renal Na+/H+ exchange in cadmium-intoxicated rats."
Ahn D.-W. , Chung J.-M. , Kim J.-Y. , Kim K.-R. , Park Y.-S.
Toxicol. Appl. Pharmacol.204:91-98(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION

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