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Index > Protein center > Slc6a13(Gene name) > Mouse
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  • Slc6a13 (Gene name),
  • Sodium- and chloride-dependent GABA transporter 2 (Protein name ),  S6A13_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Slc6a13(Gabt2;Gabt3;Gat-3;Gat2;Gat3);
    Protein name:
    Sodium- and chloride-dependent GABA transporter 2(GAT-2);
    Alternative:
    Solute carrier family 6 member 13;Sodium- and chloride-dependent GABA transporter 3(GAT-3);
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals. Can also transport beta-alanine and taurine.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    602
    Sequence:
    50:
    MENRASGTTS | NGETKPVCPA | MEKVEEDGTL | EREHWNNKME | FVLSVAGEII | 
    100:
    GLGNVWRFPY | LCYKNGGGAF | FIPYLIFLFT | CGIPVFFLET | ALGQYTNQGG | 
    150:
    ITAWRRICPI | FEGIGYASQM | IVSLLNVYYI | VVLAWALFYL | FSSFTTDLPW | 
    200:
    GSCSHEWNTE | NCVEFQKAND | SMNVTSENAT | SPVIEFWERR | VLKLSDGIQH | 
    250:
    LGSLRWELVL | CLLLAWIICY | FCIWKGVKST | GKVVYFTATF | PYLMLVVLLI | 
    300:
    RGVTLPGAAQ | GIQFYLYPNI | TRLWDPQVWM | DAGTQIFFSF | AICLGCLTAL | 
    350:
    GSYNKYHNNC | YRDCIALCIL | NSSTSFMAGF | AIFSILGFMS | QEQGVPISEV | 
    400:
    AESGPGLAFI | AYPRAVVMLP | FSPLWACCFF | FMVVLLGLDS | QFVCVESLVT | 
    450:
    ALVDMYPRVF | RKKNRREVLI | LIVSVISFFI | GLIMLTEGGM | YVFQLFDYYA | 
    500:
    ASGMCLLFVA | IFESLCVAWV | YGAGRFYDNI | EDMIGYKPWP | LIKYCWLFFT | 
    550:
    PAVCLATFLF | SLIKYTPLTY | NKKYTYPWWG | DALGWLLALS | SMICIPAWSI | 
    600:
    YKLRTLKGPL | RERLRQLVCP | AEDLPQKNQP | EPTAPATPMT | SLLRLTELES | 
    602:
    NC
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    SMR:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse GAT-2
    ELISA Kit for Mouse GAT-2
    ELISA Kit for Mouse GAT-2
    ELISA Kit for Mouse GAT-2
    CLIA Kit for Mouse GAT-2
    CLIA Kit for Mouse GAT-2
    CLIA Kit for Mouse GAT-2
    CLIA Kit for Mouse GAT-2
    Polyclonal Antibody for Mouse GAT-2
    Polyclonal Antibody for Mouse GAT-2
    Polyclonal Antibody for Mouse GAT-2
    Polyclonal Antibody for Mouse GAT-2
    Monoclonal Antibody for Mouse GAT-2
    Monoclonal Antibody for Mouse GAT-2
    Monoclonal Antibody for Mouse GAT-2
    Monoclonal Antibody for Mouse GAT-2
    Protein for Mouse GAT-2
    Protein for Mouse GAT-2
    Protein for Mouse GAT-2
    Protein for Mouse GAT-2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain."
      Liu Q.-R. , Lopez-Coecuera B. , Mandiyan S. , Nelson H. , Nelson N.
      J. Biol. Chem.268:2106-2112(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: FVB/N.
      tissue: Kidney.
      tissue: Liver.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-587;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Liver.
    4. 4.
      "Deletion of the gamma-aminobutyric acid transporter 2 (GAT2 and SLC6A13) gene in mice leads to changes in liver and brain taurine contents."
      Zhou Y. , Holmseth S. , Guo C. , Hassel B. , Hofner G. , Huitfeldt H.S. , Wanner K.T. , Danbolt N.C.
      J. Biol. Chem.287:35733-35746(2012) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DISRUPTION PHENOTYPE
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