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Index > Protein center > SLC6A2(Gene name) > Human
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  • SLC6A2 (Gene name),
  • Sodium-dependent noradrenaline transporter (Protein name ),  SC6A2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SLC6A2(NAT1;NET1;SLC6A5);
    Protein name:
    Sodium-dependent noradrenaline transporter;
    Alternative:
    Solute carrier family 6 member 2;Norepinephrine transporter(NET);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with PRKCABP.
    Function:
    Amine transporter. Terminates the action of noradrenaline by its high affinity sodium-dependent reuptake into presynaptic terminals.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    617
    Sequence:
    50:
    MLLARMNPQV | QPENNGADTG | PEQPLRARKT | AELLVVKERN | GVQCLLAPRD | 
    100:
    GDAQPRETWG | KKIDFLLSVV | GFAVDLANVW | RFPYLCYKNG | GGAFLIPYTL | 
    150:
    FLIIAGMPLF | YMELALGQYN | REGAATVWKI | CPFFKGVGYA | VILIALYVGF | 
    200:
    YYNVIIAWSL | YYLFSSFTLN | LPWTDCGHTW | NSPNCTDPKL | LNGSVLGNHT | 
    250:
    KYSKYKFTPA | AEFYERGVLH | LHESSGIHDI | GLPQWQLLLC | LMVVVIVLYF | 
    300:
    SLWKGVKTSG | KVVWITATLP | YFVLFVLLVH | GVTLPGASNG | INAYLHIDFY | 
    350:
    RLKEATVWID | AATQIFFSLG | AGFGVLIAFA | SYNKFDNNCY | RDALLTSSIN | 
    400:
    CITSFVSGFA | IFSILGYMAH | EHKVNIEDVA | TEGAGLVFIL | YPEAISTLSG | 
    450:
    STFWAVVFFV | MLLALGLDSS | MGGMEAVITG | LADDFQVLKR | HRKLFTFGVT | 
    500:
    FSTFLLALFC | ITKGGIYVLT | LLDTFAAGTS | ILFAVLMEAI | GVSWFYGVDR | 
    550:
    FSNDIQQMMG | FRPGLYWRLC | WKFVSPAFLL | FVVVVSIINF | KPLTYDDYIF | 
    600:
    PPWANWVGWG | IALSSMVLVP | IYVIYKFLST | QGSLWERLAY | GITPENEHHL | 
    617:
    VAQRDIRQFQ | LQHWLAI
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    Pfam:
    KEGG:
    String:
    UniGene:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Sodium-dependent noradrenaline transporter
    Cat.:
    E4175m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Sodium-dependent noradrenaline transporter
    Cat.:
    E4175h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Human Sodium-dependent noradrenaline transporter
    Cat.:
    E4175b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Sodium-dependent noradrenaline transporter
    Cat.:
    U4175b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Human Sodium-dependent noradrenaline transporter
    Cat.:
    U4175m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Sodium-dependent noradrenaline transporter
    Cat.:
    U4175h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Sodium-dependent noradrenaline transporter
    Polyclonal Antibody for Human Sodium-dependent noradrenaline transporter
    Cat.:
    P4175Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Sodium-dependent noradrenaline transporter
    Cat.:
    P4175Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Sodium-dependent noradrenaline transporter
    Monoclonal Antibody for Human Sodium-dependent noradrenaline transporter
    Monoclonal Antibody for Human Sodium-dependent noradrenaline transporter
    Protein for Human Sodium-dependent noradrenaline transporter
    Protein for Human Sodium-dependent noradrenaline transporter
    Protein for Human Sodium-dependent noradrenaline transporter

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Expression cloning of a cocaine- and antidepressant-sensitive human noradrenaline transporter."
      Pacholczyk T. , Blakely R.D. , Amara S.G.
      Nature350:350-354(1991) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Molecular cloning and organization of the coding region of the human norepinephrine transporter gene."
      Poerzgen P. , Boenisch H. , Bruss M.
      Biochem. Biophys. Res. Commun.215:1145-1150(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      tissue: Lung.
    3. 3.
      "The human noradrenaline transporter gene contains multiple polyadenylation sites and two alternatively spliced C-terminal exons."
      Porzgen P. , Bonisch H. , Hammermann R. , Bruss M.
      Biochim. Biophys. Acta1398:365-370(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] (ISOFORM 2);ALTERNATIVE SPLICING
      tissue: Lung.
    4. 4.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3)
      tissue: Testis.
    5. 5.
      "The sequence and analysis of duplication-rich human chromosome 16."
      Martin J. , Han C. , Gordon L.A. , Terry A. , Prabhakar S. , She X. , Xie G. , Hellsten U. , Chan Y.M. , Altherr M. , Couronne O. , Aerts A. , Bajorek E. , Black S. , Blumer H. , Branscomb E. , Brown N.C. , Bruno W.J. , more...
      Nature432:988-994(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "Functional interaction between monoamine plasma membrane transporters and the synaptic PDZ domain-containing protein PICK1."
      Torres G.E. , Yao W.-D. , Mohn A.R. , Quan H. , Kim K.-M. , Levey A.I. , Staudinger J. , Caron M.G.
      Neuron30:121-134(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PRKCABP
    8. 8.
      "Orthostatic intolerance and tachycardia associated with norepinephrine-transporter deficiency."
      Shannon J.R. , Flattem N.L. , Jordan J. , Jacob G. , Black B.K. , Biaggioni I. , Blakely R.D. , Robertson D.
      N. Engl. J. Med.342:541-549(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: VARIANT OI PRO-457
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