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Index > Protein center > Slc6a3(Gene name) > Mouse
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  • Slc6a3 (Gene name),
  • Sodium-dependent dopamine transporter (Protein name ),  SC6A3_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Slc6a3(Dat;Dat1);
    Protein name:
    Sodium-dependent dopamine transporter(DA transporter;DAT);
    Alternative:
    Solute carrier family 6 member 3;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Homooligomer; disulfide-linked. Interacts with PRKCABP (By similarity). Interacts with TGFB1I1. Interacts (via N-terminus) with SYNGR3 (via N-terminus). Interacts with SLC18A2.
    Function:
    Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
    Subcellular Location:
    Membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    619
    Sequence:
    50:
    MSKSKCSVGP | MSSVVAPAKE | PNAVGPREVE | LILVKEQNGV | QLTNSTLINP | 
    100:
    PQTPVEVQER | ETWSKKIDFL | LSVIGFAVDL | ANVWRFPYLC | YKNGGGAFLV | 
    150:
    PYLLFMVIAG | MPLFYMELAL | GQFNREGAAG | VWKICPVLKG | VGFTVILISF | 
    200:
    YVGFFYNVII | AWALHYFFSS | FTMDLPWIHC | NNTWNSPNCS | DAHSSNSSDG | 
    250:
    LGLNDTFGTT | PAAEYFERGV | LHLHQSRGID | DLGPPRWQLT | ACLVLVIVLL | 
    300:
    YFSLWKGVKT | SGKVVWITAT | MPYVVLTALL | LRGVTLPGAM | DGIRAYLSVD | 
    350:
    FYRLCEASVW | IDAATQVCFS | LGVGFGVLIA | FSSYNKFTNN | CYRDAIITTS | 
    400:
    INSLTSFSSG | FVVFSFLGYM | AQKHNVPIRD | VATDGPGLIF | IIYPEAIATL | 
    450:
    PLSSAWAAVF | FLMLLTLGID | SAMGGMESVI | TGLVDEFQLL | HRHRELFTLG | 
    500:
    IVLATFLLSL | FCVTNGGIYV | FTLLDHFAAG | TSILFGVLIE | AIGVAWFYGV | 
    550:
    QQFSDDIKQM | TGQRPNLYWR | LCWKLVSPCF | LLYVVVVSIV | TFRPPHYGAY | 
    600:
    IFPDWANALG | WIIATSSMAM | VPIYATYKFC | SLPGSFREKL | AYAITPEKDR | 
    619:
    QLVDRGEVRQ | FTLRHWLLV
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    SMR:
    KEGG:
    UniGene:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse DA transporter
    Cat.:
    E1625r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse DA transporter
    Cat.:
    E1625h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse DA transporter
    Cat.:
    E1625b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    ELISA Kit for Mouse DA transporter
    Cat.:
    E1625m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse DA transporter
    Cat.:
    U1625b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse DA transporter
    Cat.:
    U1625r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse DA transporter
    Cat.:
    U1625h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse DA transporter
    Cat.:
    U1625m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse DA transporter
    Cat.:
    P1625Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse DA transporter
    Cat.:
    P1625Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse DA transporter
    Cat.:
    P1625Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse DA transporter
    Monoclonal Antibody for Mouse DA transporter
    Monoclonal Antibody for Mouse DA transporter
    Monoclonal Antibody for Mouse DA transporter
    Monoclonal Antibody for Mouse DA transporter
    Protein for Mouse DA transporter
    Protein for Mouse DA transporter
    Protein for Mouse DA transporter
    Protein for Mouse DA transporter

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    References
    1. 1.
      "Molecular cloning of the mouse dopamine transporter and pharmacological comparison with the human homologue."
      Wu X. , Gu H.H.
      Gene233:163-170(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: C57BL/6J.
      tissue: Brain.
    2. 2.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Brain.
    3. 3.
      "Human and mouse dopamine transporter genes: conservation of 5'-flanking sequence elements and gene structures."
      Donovan D.M. , Vandenbergh D.J. , Perry M.P. , Bird G.S. , Ingersoll R. , Nanthakumar E. , Uhl G.R.
      Brain Res. Mol. Brain Res.30:327-335(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-343
      strain: BALB/c.
      tissue: Brain.
    4. 4.
      "The multiple LIM domain-containing adaptor protein Hic-5 synaptically colocalizes and interacts with the dopamine transporter."
      Carneiro A.M.D. , Ingram S.L. , Beaulieu J.-M. , Sweeney A. , Amara S.G. , Thomas S.M. , Caron M.G. , Torres G.E.
      J. Neurosci.22:7045-7054(2002) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TGFB1I1
    5. 5.
      "Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3."
      Egana L.A. , Cuevas R.A. , Baust T.B. , Parra L.A. , Leak R.K. , Hochendoner S. , Pena K. , Quiroz M. , Hong W.C. , Dorostkar M.M. , Janz R. , Sitte H.H. , Torres G.E.
      J. Neurosci.29:4592-4604(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SYNGR3 AND SLC18A2;TISSUE SPECIFICITY
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