Gene name:
Slc6a3 (Dat;Dat1) ;
Protein name:
Sodium-dependent dopamine transporter (DA transporter;DAT) ;
Alternative:
Solute carrier family 6 member 3 ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Homooligomer; disulfide-linked. Interacts with PRKCABP (By similarity). Interacts with TGFB1I1. Interacts (via N-terminus) with SYNGR3 (via N-terminus). Interacts with SLC18A2.
Function:
Amine transporter. Terminates the action of dopamine by its high affinity sodium-dependent reuptake into presynaptic terminals.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MSKSKCSVGP | MSSVVAPAKE | PNAVGPREVE | LILVKEQNGV | QLTNSTLINP |
100:
PQTPVEVQER | ETWSKKIDFL | LSVIGFAVDL | ANVWRFPYLC | YKNGGGAFLV |
150:
PYLLFMVIAG | MPLFYMELAL | GQFNREGAAG | VWKICPVLKG | VGFTVILISF |
200:
YVGFFYNVII | AWALHYFFSS | FTMDLPWIHC | NNTWNSPNCS | DAHSSNSSDG |
250:
LGLNDTFGTT | PAAEYFERGV | LHLHQSRGID | DLGPPRWQLT | ACLVLVIVLL |
300:
YFSLWKGVKT | SGKVVWITAT | MPYVVLTALL | LRGVTLPGAM | DGIRAYLSVD |
350:
FYRLCEASVW | IDAATQVCFS | LGVGFGVLIA | FSSYNKFTNN | CYRDAIITTS |
400:
INSLTSFSSG | FVVFSFLGYM | AQKHNVPIRD | VATDGPGLIF | IIYPEAIATL |
450:
PLSSAWAAVF | FLMLLTLGID | SAMGGMESVI | TGLVDEFQLL | HRHRELFTLG |
500:
IVLATFLLSL | FCVTNGGIYV | FTLLDHFAAG | TSILFGVLIE | AIGVAWFYGV |
550:
QQFSDDIKQM | TGQRPNLYWR | LCWKLVSPCF | LLYVVVVSIV | TFRPPHYGAY |
600:
IFPDWANALG | WIIATSSMAM | VPIYATYKFC | SLPGSFREKL | AYAITPEKDR |
619:
QLVDRGEVRQ | FTLRHWLLV
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
Bovine
Mouse
ELISA Kit for Mouse DA transporter
ELISA Kit for Mouse DA transporter
ELISA Kit for Mouse DA transporter
ELISA Kit for Mouse DA transporter
CLIA Kit for Mouse DA transporter
CLIA Kit for Mouse DA transporter
CLIA Kit for Mouse DA transporter
CLIA Kit for Mouse DA transporter
Polyclonal Antibody for Mouse DA transporter
Polyclonal Antibody for Mouse DA transporter
Polyclonal Antibody for Mouse DA transporter
Polyclonal Antibody for Mouse DA transporter
Monoclonal Antibody for Mouse DA transporter
Monoclonal Antibody for Mouse DA transporter
Monoclonal Antibody for Mouse DA transporter
Monoclonal Antibody for Mouse DA transporter
Protein for Mouse DA transporter
Protein for Mouse DA transporter
Protein for Mouse DA transporter
Protein for Mouse DA transporter
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
C57BL/6J .
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Brain .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-343
strain :
BALB/c .
tissue :
Brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH TGFB1I1
5.
"Physical and functional interaction between the dopamine transporter and the synaptic vesicle protein synaptogyrin-3."
Egana L.A.
,
Cuevas R.A.
,
Baust T.B.
,
Parra L.A.
,
Leak R.K.
,
Hochendoner S.
,
Pena K.
,
Quiroz M.
,
Hong W.C.
,
Dorostkar M.M.
,
Janz R.
,
Sitte H.H.
,
Torres G.E.
J. Neurosci.29:4592-4604(2009)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH SYNGR3 AND SLC18A2;TISSUE SPECIFICITY