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Index > Protein center > SCAPER(Gene name) > Human
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  • SCAPER (Gene name),
  • S phase cyclin A-associated protein in the endoplasmic reticulum (Protein name ),  SCAPE_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    SCAPER(MSTP063;KIAA1454;ZNF291);
    Protein name:
    S phase cyclin A-associated protein in the endoplasmic reticulum(S phase cyclin A-associated protein in the ER);
    Alternative:
    Zinc finger protein 291;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Interacts with CCNA2/CDK2 complex, but not with CCNA2/CDC2, CCNB1/CDC2 or CCNE1/CDK2 complexes, at multiple phases of the cell cycle, including S and G2/M.
    Function:
    CCNA2/CDK2 regulatory protein that transiently maintains CCNA2 in the cytoplasm.
    Subcellular Location:
    Endoplasmic reticulum Nucleus Predominantly located in the endoplasmic reticulum, only a small portion is detected in the nucleus.
    Protein Attributes:
    Sequence length:
    1399
    Sequence:
    50:
    MASFQRSNSH | DKVRRIVAEE | GRTARNLIAW | SVPLESKDDD | GKPKCQTGGK | 
    100:
    SKRTIQGTHK | TTKQSTAVDC | KITSSTTGDK | HFDKSPTKTR | HPRKIDLRAR | 
    150:
    YWAFLFDNLR | RAVDEIYVTC | ESDQSVVECK | EVLMMLDNYV | RDFKALIDWI | 
    200:
    QLQEKLEKTD | AQSRPTSLAW | EVKKMSPGRH | VIPSPSTDRI | NVTSNARRSL | 
    250:
    NFGGSTGTVP | APRLAPTGVS | WADKVKAHHT | GSTASSEITP | AQSCPPMTVQ | 
    300:
    KASRKNERKD | AEGWETVQRG | RPIRSRSTAV | MPKVSLATEA | TRSKDDSDKE | 
    350:
    NVCLLPDESI | QKGQFVGDGT | SNTIESHPKD | SLHSCDHPLA | EKTQFTVSTL | 
    400:
    DDVKNSGSIR | DNYVRTSEIS | AVHIDTECVS | VMLQAGTPPL | QVNEEKFPAE | 
    450:
    KARIENEMDP | SDISNSMAEV | LAKKEELADR | LEKANEEAIA | SAIAEEEQLT | 
    500:
    REIEAEENND | INIETDNDSD | FSASMGSGSV | SFCGMSMDWN | DVLADYEARE | 
    550:
    SWRQNTSWGD | IVEEEPARPP | GHGIHMHEKL | SSPSRKRTIA | ESKKKHEEKQ | 
    600:
    MKAQQLREKL | REEKTLKLQK | LLEREKDVRK | WKEELLDQRR | RMMEEKLLHA | 
    650:
    EFKREVQLQA | IVKKAQEEEA | KVNEIAFINT | LEAQNKRHDV | LSKLKEYEQR | 
    700:
    LNELQEERQR | RQEEKQARDE | AVQERKRALE | AERQARVEEL | LMKRKEQEAR | 
    750:
    IEQQRQEKEK | AREDAARERA | RDREERLAAL | TAAQQEAMEE | LQKKIQLKHD | 
    800:
    ESIRRHMEQI | EQRKEKAAEL | SSGRHANTDY | APKLTPYERK | KQCSLCNVLI | 
    850:
    SSEVYLFSHV | KGRKHQQAVR | ENTSIQGREL | SDEEVEHLSL | KKYIIDIVVE | 
    900:
    STAPAEALKD | GEERQKNKKK | AKKIKARMNF | RAKEYESLME | TKNSGSDSPY | 
    950:
    KAKLQRLAKD | LLKQVQVQDS | GSWANNKVSA | LDRTLGEITR | ILEKENVADQ | 
    1000:
    IAFQAAGGLT | ALEHILQAVV | PATNVNTVLR | IPPKSLCNAI | NVYNLTCNNC | 
    1050:
    SENCSDVLFS | NKITFLMDLL | IHQLTVYVPD | ENNTILGRNT | NKQVFEGLTT | 
    1100:
    GLLKVSAVVL | GCLIANRPDG | NCQPATPKIP | TQEMKNKPSQ | GDPFNNRVQD | 
    1150:
    LISYVVNMGL | IDKLCACFLS | VQGPVDENPK | MAIFLQHAAG | LLHAMCTLCF | 
    1200:
    AVTGRSYSIF | DNNRQDPTGL | TAALQATDLA | GVLHMLYCVL | FHGTILDPST | 
    1250:
    ASPKENYTQN | TIQVAIQSLR | FFNSFAALHL | PAFQSIVGAE | GLSLAFRHMA | 
    1300:
    SSLLGHCSQV | SCESLLHEVI | VCVGYFTVNH | PDNQVIVQSG | RHPTVLQKLC | 
    1350:
    QLPFQYFSDP | RLIKVLFPSL | IAACYNNHQN | KIILEQEMSC | VLLATFIQDL | 
    1399:
    AQTPGQAENQ | PYQPKGKCLG | SQDYLELANR | FPQQAWEEAR | QFFLKKEKK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    KEGG:
    String:
    MIM:
    Uniprot:
     
    FOR
    ELISA Kit for Human S phase cyclin A-associated protein in the ER
    CLIA Kit for Human S phase cyclin A-associated protein in the ER
    Polyclonal Antibody for Human S phase cyclin A-associated protein in the ER
    Monoclonal Antibody for Human S phase cyclin A-associated protein in the ER
    Protein for Human S phase cyclin A-associated protein in the ER

    R&D Technical Data
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    Precision
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    Recovery
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    References
    1. 1.
      "Identification and characterization of ZNF291, a novel protein on chromosome 15q24."
      Carim-Todd L. , Sumoy L. , Estivill X. , Escarceller M.
      Submitted (2000-03) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
    2. 2.
      "Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro."
      Nagase T. , Kikuno R. , Ishikawa K. , Hirosawa M. , Ohara O.
      DNA Res.7:143-150(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2);VARIANT THR-1089
      tissue: Brain.
    3. 3.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1135-1400 (ISOFORM 1)
      tissue: Retina.
      tissue: Testis.
    4. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 6.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-551 AND 1024-1340 (ISOFORM 1)
      tissue: Colon.
      tissue: Prostate.
    6. 7.
      Zhao B. , Xu Y.Y. , Liu Y.Q. , Wang X.Y. , Lui B. , Ye J. , Song L. , Zhao Y. , Cao H.Q. , Zhao X.W. , Gao Y. , Zhang C.L. , Zhang J. , Liu L.S. , Ding J.F. , Gao R.L. , Wu Q.Y. , Qiang B.Q. , more...
      Submitted (1999-01) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 246-1340 (ISOFORM 1);VARIANT THR-1089
      tissue: Heart.
    7. 8.
      "Cloning of human full-length CDSs in BD Creator(TM) system donor vector."
      Kalnine N. , Chen X. , Rolfs A. , Halleck A. , Hines L. , Eisenstein S. , Koundinya M. , Raphael J. , Moreira D. , Kelley T. , LaBaer J. , Lin Y. , Phelan M. , Farmer A.
      Submitted (2003-05) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1109-1400 (ISOFORM 1)
    8. 9.
      "SCAPER, a novel cyclin A-interacting protein that regulates cell cycle progression."
      Tsang W.Y. , Wang L. , Chen Z. , Sanchez I. , Dynlacht B.D.
      J. Cell Biol.178:621-633(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH CCNA2/CDK2 COMPLEX;SUBCELLULAR LOCATION;TISSUE SPECIFICITY;DEVELOPMENTAL STAGE;MUTAGENESIS OF 26-ARG--LEU-28; 199-ARG--LEU-201 AND 678-ARG--LEU-680
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