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Index > Protein center > Scfd1(Gene name) > Rat
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  • Scfd1 (Gene name),
  • Sec1 family domain-containing protein 1 (Protein name ),  SCFD1_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Scfd1(Ra410;Sly1;Stxbp1l2);
    Protein name:
    Sec1 family domain-containing protein 1;
    Alternative:
    Syntaxin-binding protein 1-like 2;SLY1 homolog(Sly1p);Vesicle transport-related protein Ra410;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with the COG complex via COG4. Binds STX5A.
    Function:
    Plays a role in SNARE-pin assembly and Golgi-to-ER retrograde transport via its interaction with COG4. Involved in vesicular transport between the endoplasmic reticulum and the Golgi.
    Subcellular Location:
    Cytoplasm Endoplasmic reticulum membrane Peripheral membrane protein Golgi apparatus Golgi stack membrane Peripheral membrane protein
    Protein Attributes:
    Sequence length:
    637
    Sequence:
    50:
    MVGSKMAASI | RERQTVALKR | MLNFNVPHVK | NSPGEPVWKV | LIYDRFGQDI | 
    100:
    ISPLLSVKEL | RDMGITLHLL | LHSDRDPIRD | VPAVYFVMPT | EENIDRLCQD | 
    150:
    LRNQLYESYY | LNFISAISRS | KLEDIANAAL | AANAVTQVAK | VFDQYLNFIT | 
    200:
    LEEDMFVLCN | QNKELVSYRA | INRPDITDTE | METVMDTIVD | SLFCFFVTLG | 
    250:
    AVPIIRCSRG | TAAEMVAVKL | DKKLRENLRD | ARNSLFTGDP | LGTGQFSFQR | 
    300:
    PLLVLVDRNI | DLATPLHHTW | TYQALVHDVL | DFHLNRVNLE | ESTGVENSPT | 
    350:
    GARPKRKNKK | SYDLTPVDKF | WQKHKGSPFP | EVAESVQQEL | ESYRAQEDEV | 
    400:
    KRLKSIMGLE | GEDEGAISML | SDNTAKLTSA | VSSLPELLEK | KRLIDLHTNV | 
    450:
    ATAVLEHIKA | RKLDVYFEYE | EKIMSKTTLD | KSLLDVISDP | DAGTPEDKMR | 
    500:
    LFLIYYISAQ | QAPSEVDLEQ | YKKALTDAGC | NLSPLQYIKQ | WKAFAKMAST | 
    550:
    PASYGNTTTK | PMGLLSRVMN | TGSQFVMEGV | KNLVLKQQNL | PVTRILDNLM | 
    600:
    EMKSNPETDD | YRYFDPKMLR | SNDSSVPRNK | SPFQEAIVFV | VGGGNYIEYQ | 
    637:
    NLVDYIKGKQ | GKHILYGCSE | IFNATQFIKQ | LSQLGQK
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    UniGene:
    Pfam:
    String:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Sec1 family domain-containing protein 1
    ELISA Kit for Rat Sec1 family domain-containing protein 1
    ELISA Kit for Rat Sec1 family domain-containing protein 1
    CLIA Kit for Rat Sec1 family domain-containing protein 1
    CLIA Kit for Rat Sec1 family domain-containing protein 1
    CLIA Kit for Rat Sec1 family domain-containing protein 1
    Polyclonal Antibody for Rat Sec1 family domain-containing protein 1
    Polyclonal Antibody for Rat Sec1 family domain-containing protein 1
    Polyclonal Antibody for Rat Sec1 family domain-containing protein 1
    Monoclonal Antibody for Rat Sec1 family domain-containing protein 1
    Monoclonal Antibody for Rat Sec1 family domain-containing protein 1
    Monoclonal Antibody for Rat Sec1 family domain-containing protein 1
    Protein for Rat Sec1 family domain-containing protein 1
    Protein for Rat Sec1 family domain-containing protein 1
    Protein for Rat Sec1 family domain-containing protein 1

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Mammalian Sly1 regulates syntaxin 5 function in endoplasmic reticulum to Golgi transport."
      Dascher C. , Balch W.E.
      J. Biol. Chem.271:15866-15869(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];PROTEIN SEQUENCE OF 21-30; 81-92; 211-219 AND 554-561;FUNCTION;INTERACTION WITH STX5A
      strain: Sprague-Dawley.
      tissue: Liver.
    2. 2.
      "Cloning of a putative vesicle transport-related protein, RA410, from cultured rat astrocytes and its expression in ischemic rat brain."
      Matsuo N. , Ogawa S. , Takagi T. , Wanaka A. , Mori T. , Matsuyama T. , Pinsky D.J. , Stern D.M. , Tohyama M.
      J. Biol. Chem.272:16438-16444(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];FUNCTION;INDUCTION;TISSUE SPECIFICITY;SUBCELLULAR LOCATION
      tissue: Brain.
    3. 3.
      "A mammalian homologue of SLY1, a yeast gene required for transport from endoplasmic reticulum to Golgi."
      Peterson M.R. , Hsu S.C. , Scheller R.H.
      Gene169:293-294(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 9-637;TISSUE SPECIFICITY
      tissue: Brain.
    4. 4.
      "Syntaxin 17 is abundant in steroidogenic cells and implicated in smooth endoplasmic reticulum membrane dynamics."
      Steegmaier M. , Oorschot V. , Klumperman J. , Scheller R.H.
      Mol. Biol. Cell11:2719-2731(2000) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH STX17
    5. 5.
      "Direct interaction between the COG complex and the SM protein, Sly1, is required for Golgi SNARE pairing."
      Laufman O. , Kedan A. , Hong W. , Lev S.
      EMBO J.28:2006-2017(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH COG4
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