Protein name:
Sodium channel protein type 1 subunit alpha ;
Alternative:
Sodium channel protein type I subunit alpha ;Sodium channel protein brain I subunit alpha ;Voltage-gated sodium channel subunit alpha Nav1.1 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
The sodium channel consists of a large polypeptide and 2-3 smaller ones. This sequence represents a large polypeptide.
Function:
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient.
Subcellular Location:
Membrane
Multi-pass membrane protein
Protein Attributes:
50:
MEQTVLVPPG | PDSFNFFTRE | SLAAIERRIA | EEKAKNPKPD | KKDDDENGPK |
100:
PNSDLEAGKN | LPFIYGDIPP | EMVSEPLEDL | DPYYINKKTF | IVLNKGKAIF |
150:
RFSATSALYI | LTPFNPLRKI | AIKILVHSLF | SMLIMCTILT | NCVFMTMSNP |
200:
PDWTKNVEYT | FTGIYTFESL | IKIIARGFCL | EDFTFLRDPW | NWLDFTVITF |
250:
AYVTEFVDLG | NVSALRTFRV | LRALKTISVI | PGLKTIVGAL | IQSVKKLSDV |
300:
MILTVFCLSV | FALIGLQLFM | GNLRNKCVQW | PPTNASLEEH | SIEKNVTTDY |
350:
NGTLVNETVF | EFDWKSYIQD | SRYHYFLEGV | LDALLCGNSS | DAGQCPEGYM |
400:
CVKAGRNPNY | GYTSFDTFSW | AFLSLFRLMT | QDFWENLYQL | TLRAAGKTYM |
450:
IFFVLVIFLG | SFYLINLILA | VVAMAYEEQN | QATLEEAEQK | EAEFQQMLEQ |
500:
LKKQQEAAQQ | AAAATASEHS | REPSAAGRLS | DSSSEASKLS | SKSAKERRNR |
550:
RKKRKQKEQS | GGEEKDDDEF | HKSESEDSIR | RKGFRFSIEG | NRLTYEKRYS |
600:
SPHQSLLSIR | GSLFSPRRNS | RTSLFSFRGR | AKDVGSENDF | ADDEHSTFED |
650:
NESRRDSLFV | PRRHGERRNS | NLSQTSRSSR | MLAGLPANGK | MHSTVDCNGV |
700:
VSLVGGPSVP | TSPVGQLLPE | VIIDKPATDD | NGTTTETEMR | KRRSSSFHVS |
750:
MDFLEDPSQR | QRAMSIASIL | TNTVEELEES | RQKCPPCWYK | FSNIFLIWDC |
800:
SPYWLKVKHI | VNLVVMDPFV | DLAITICIVL | NTLFMAMEHY | PMTEHFNHVL |
850:
TVGNLVFTGI | FTAEMFLKII | AMDPYYYFQE | GWNIFDGFIV | TLSLVELGLA |
900:
NVEGLSVLRS | FRLLRVFKLA | KSWPTLNMLI | KIIGNSVGAL | GNLTLVLAII |
950:
VFIFAVVGMQ | LFGKSYKDCV | CKIATDCKLP | RWHMNDFFHS | FLIVFRVLCG |
1000:
EWIETMWDCM | EVAGQAMCLT | VFMMVMVIRN | LVVLNLFLAL | LLSSFSADNL |
1050:
AATDDDNEMN | NLQIAVDRMH | KGVAYVKRKI | YEFIQQSFVR | KQKILDEIKP |
1100:
LDDLNNRKDN | CTSNHTTEIG | KDLDCLKDVN | GTTSGIGTGS | SVEKYIIDES |
1150:
DYMSFINNPS | LTVTVPIAVG | ESDFENLNTE | DFSSESDLEE | SKEKLNESSS |
1200:
SSEGSTVDIG | APAEEQPVME | PEETLEPEAC | FTEGCVQRFK | CCQISVEEGR |
1250:
GKQWWNLRRT | CFRIVEHNWF | ETFIVFMILL | SSGALAFEDI | YIDQRKTIKT |
1300:
MLEYADKVFT | YIFILEMLLK | WVAYGYQTYF | TNAWCWLDFL | IVDVSLVSLT |
1350:
ANALGYSELG | AIKSLRTLRA | LRPLRALSRF | EGMRVVVNAL | LGAIPSIMNV |
1400:
LLVCLIFWLI | FSIMGVNLFA | GKFYHCVNTT | TGDTFEITEV | NNHSDCLKLI |
1450:
ERNETARWKN | VKVNFDNVGF | GYLSLLQVAT | FKGWMDIMYA | AVDSRNVELQ |
1500:
PKYEESLYMY | LYFVIFIIFG | SFFTLNLFIG | VIIDNFNQQK | KKFGGQDIFM |
1550:
TEEQKKYYNA | MKKLGSKKPQ | KPIPRPGNKF | QGMVFDFVTR | QVFDISIMIL |
1600:
ICLNMVTMMV | ETDDQSDYVT | SILSRINLVF | IVLFTGECVL | KLISLRHYYF |
1650:
TIGWNIFDFV | VVILSIVGMF | LAELIEKYFV | SPTLFRVIRL | ARIGRILRLI |
1700:
KGAKGIRTLL | FALMMSLPAL | FNIGLLLFLV | MFIYAIFGMS | NFAYVKREVG |
1750:
IDDMFNFETF | GNSMICLFQI | TTSAGWDGLL | APILNSKPPD | CDPNKVNPGS |
1800:
SVKGDCGNPS | VGIFFFVSYI | IISFLVVVNM | YIAVILENFS | VATEESAEPL |
1850:
SEDDFEMFYE | VWEKFDPDAT | QFMEFEKLSQ | FAAALEPPLN | LPQPNKLQLI |
1900:
AMDLPMVSGD | RIHCLDILFA | FTKRVLGESG | EMDALRIQME | ERFMASNPSK |
1950:
VSYQPITTTL | KRKQEEVSAV | IIQRAYRRHL | LKRTVKQASF | TYNKNKLKGG |
2000:
ANLLVKEDMI | IDRINENSIT | EKTDLTMSTA | ACPPSYDRVT | KPIVEKHEQE |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Rat
Human
ELISA Kit for Rat Sodium channel protein type 1 subunit alpha
ELISA Kit for Rat Sodium channel protein type 1 subunit alpha
CLIA Kit for Rat Sodium channel protein type 1 subunit alpha
CLIA Kit for Rat Sodium channel protein type 1 subunit alpha
Polyclonal Antibody for Rat Sodium channel protein type 1 subunit alpha
Polyclonal Antibody for Rat Sodium channel protein type 1 subunit alpha
Monoclonal Antibody for Rat Sodium channel protein type 1 subunit alpha
Monoclonal Antibody for Rat Sodium channel protein type 1 subunit alpha
Protein for Rat Sodium channel protein type 1 subunit alpha
Protein for Rat Sodium channel protein type 1 subunit alpha
R&D Technical Data
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Precision
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Recovery
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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Linearity
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For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 177-253
strain :
Sprague-Dawley .
tissue :
Brain .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION AT SER-470; SER-551 AND SER-607