Protein name:
Sodium channel subunit beta-3 ;
Alternative:
Organism:
Bovine (Bos taurus).
General Annotation
Sub Unit:
The voltage-sensitive sodium channel consists of an ion conducting pore forming alpha-subunit regulated by one or more beta-1, beta-2 and/or beta-3 subunits. Beta-1 and beta-3 are non-covalently associated with alpha, while beta-2 is covalently linked by disulfide bonds. Beta-1 or beta-3 subunits associate with neurofascin. Associates with SCN10A.
Function:
Modulates channel gating kinetics. Causes unique persistent sodium currents. Inactivates the sodium channel opening more slowly than the subunit beta-1. Its association with neurofascin may target the sodium channels to the nodes of Ranvier of developing axons and retain these channels at the nodes in mature myelinated axons.
Subcellular Location:
Membrane
Single-pass type I membrane protein
Protein Attributes:
50:
MPAFNRLFPL | ASLLLILWVG | VCFPVCVEVP | SETEAVQGNP | MKLRCISCMK |
100:
REEVEATTVV | EWFYRPEGGK | DFLIYEYRNG | HQEVESPFQG | RLQWNGSKDL |
150:
QDVSITVLNV | TLNDSGLYTC | NVSREFEFEA | HRPFVKTTRL | IPLRVTEEAG |
200:
EDFTSVVSEI | MMYILLVFLT | LWLLIEMIYC | YRKVSKAEEA | AQENASDYLA |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Rat
Mouse
ELISA Kit for Bovine Sodium channel subunit beta-3
ELISA Kit for Bovine Sodium channel subunit beta-3
ELISA Kit for Bovine Sodium channel subunit beta-3
ELISA Kit for Bovine Sodium channel subunit beta-3
CLIA Kit for Bovine Sodium channel subunit beta-3
CLIA Kit for Bovine Sodium channel subunit beta-3
CLIA Kit for Bovine Sodium channel subunit beta-3
CLIA Kit for Bovine Sodium channel subunit beta-3
Polyclonal Antibody for Bovine Sodium channel subunit beta-3
Polyclonal Antibody for Bovine Sodium channel subunit beta-3
Polyclonal Antibody for Bovine Sodium channel subunit beta-3
Polyclonal Antibody for Bovine Sodium channel subunit beta-3
Monoclonal Antibody for Bovine Sodium channel subunit beta-3
Monoclonal Antibody for Bovine Sodium channel subunit beta-3
Monoclonal Antibody for Bovine Sodium channel subunit beta-3
Monoclonal Antibody for Bovine Sodium channel subunit beta-3
Protein for Bovine Sodium channel subunit beta-3
Protein for Bovine Sodium channel subunit beta-3
Protein for Bovine Sodium channel subunit beta-3
Protein for Bovine Sodium channel subunit beta-3
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
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Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
Hereford .
tissue :
Heart ventricle .