Scn11a ELISA Kit for Mouse(Mus musculus) | EIAab.comScn11a ELISA Kit for Mouse(Mus musculus)

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Scn11a (Gene name),

Sodium channel protein type 11 subunit alpha (Protein name ), SCNBA_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Scn11a(Nan;Nat;Sns2);

Protein name:

Sodium channel protein type 11 subunit alpha;

Alternative:

Sensory neuron sodium channel 2;NaN;Voltage-gated sodium channel subunit alpha Nav1.9;Sodium channel protein type XI subunit alpha;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

The voltage-resistant sodium channel consists of an ion conducting pore forming alpha-subunit regulated by one or more auxiliary subunits SCN1B, SCN2B and SCN3B.

Function:

This protein mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform. Also involved, with the contribution of the receptor tyrosine kinase NTRK2, in rapid BDNF-evoked neuronal depolarization.

Subcellular Location:

Membrane Multi-pass membrane protein

Protein Attributes:

Sequence length:

1765

Sequence:

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1750:

1765:

DLSSLDVPKI | KVHCD

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9R053

Pfam:

PF00520

SMR:

Q9R053

UniGene:

Mm.89981

KEGG:

mmu:24046

Uniprot:

Q9R053

FOR

ELISA Kit for Mouse Sodium channel protein type 11 subunit alpha

CLIA Kit for Mouse Sodium channel protein type 11 subunit alpha

Polyclonal Antibody for Mouse Sodium channel protein type 11 subunit alpha

Monoclonal Antibody for Mouse Sodium channel protein type 11 subunit alpha

Protein for Mouse Sodium channel protein type 11 subunit alpha

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Coding sequence, genomic organization, and conserved chromosomal localization of the mouse gene Scn11a encoding the sodium channel NaN."
Dib-Hajj S.D. , Tyrrell L. , Escayg A. , Wood P.M. , Meisler M.H. , Waxman S.G.
Genomics59:309-318(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: ICR.
tissue: Trigeminal ganglion.
2.

"Cloning and expression study of the mouse tetrodotoxin-resistant voltage-gated sodium channel alpha subunit NaT/Scn11a."
Ogata K. , Jeong S.-Y. , Murakami H. , Hashida H. , Suzuki T. , Masuda N. , Hirai M. , Isahara K. , Uchiyama Y. , Goto J. , Kanazawa I.
Biochem. Biophys. Res. Commun.267:271-277(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];TISSUE SPECIFICITY;DEVELOPMENTAL STAGE
tissue: Testis.
3.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
4.

"Patterned electrical activity modulates sodium channel expression in sensory neurons."
Klein J.P. , Tendi E.A. , Dib-Hajj S.D. , Fields R.D. , Waxman S.G.
J. Neurosci. Res.74:192-198(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INDUCTION
5.

"Na+ channel Nav1.9: in search of a gating mechanism."
Delmas P. , Coste B.
Trends Neurosci.26:55-57(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW

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