Protein name:
Amiloride-sensitive sodium channel subunit gamma ;
Alternative:
Gamma-NaCH ;Epithelial Na(+) channel subunit gamma (Gamma-ENaC) ;SCNEG ;Nonvoltage-gated sodium channel 1 subunit gamma ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Sub Unit:
Probable heterotrimer containing one alpha, one beta and one gamma subunit. A delta subunit can replace the alpha subunit. Interacts with the WW domains of NEDD4, NEDD4L, WWP1 and WWP2.
Function:
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Subcellular Location:
Apical cell membrane
Multi-pass membrane protein
Apical membrane of epithelial cells.
Protein Attributes:
50:
MAPGEKIKAK | IKKNLPVRGP | QAPTIKDLMH | WYCMNTNTHG | CRRIVVSRGR |
100:
LRRLLWIAFT | LTAVALIIWQ | CALLVFSFYT | VSVSIKVHFQ | KLDFPAVTIC |
150:
NINPYKYSAV | SDLLTDLDSE | TKQALLSLYG | VKESRKRREA | GSMPSTLEGT |
200:
PPRFFKLIPL | LVFNENEKGK | ARDFFTGRKR | KISGKIIHKA | SNVMHVHESK |
250:
KLVGFQLCSN | DTSDCATYTF | SSGINAIQEW | YKLHYMNIMA | QVPLEKKINM |
300:
SYSAEELLVT | CFFDGMSCDA | RNFTLFHHPM | YGNCYTFNNK | ENATILSTSM |
350:
GGSEYGLQVI | LYINEDEYNP | FLVSSTGAKV | LIHQQNEYPF | IEDVGMEIET |
400:
AMSTSIGMHL | TESFKLSEPY | SQCTEDGSDV | PVTNIYNAAY | SLQICLYSCF |
450:
QTKMVEKCGC | AQYSQPLPPA | ANYCNYQQHP | NWMYCYYQLY | QAFVREELGC |
500:
QSVCKQSCSF | KEWTLTTSLA | QWPSEASEKW | LLNVLTWDQS | QQINKKLNKT |
550:
DLAKLLIFYK | DLNQRSIMES | PANSIEMLLS | NFGGQLGLWM | SCSVVCVIEI |
600:
IEVFFIDFFS | IIARRQWHKA | KDWWARRQTP | PSTETPSSRQ | GQDNPALDTD |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Mouse
Human
Rabbit
Rat
ELISA Kit for Rat Amiloride-sensitive sodium channel subunit gamma
ELISA Kit for Rat Amiloride-sensitive sodium channel subunit gamma
ELISA Kit for Rat Amiloride-sensitive sodium channel subunit gamma
ELISA Kit for Rat Amiloride-sensitive sodium channel subunit gamma
CLIA Kit for Rat Amiloride-sensitive sodium channel subunit gamma
CLIA Kit for Rat Amiloride-sensitive sodium channel subunit gamma
CLIA Kit for Rat Amiloride-sensitive sodium channel subunit gamma
CLIA Kit for Rat Amiloride-sensitive sodium channel subunit gamma
Polyclonal Antibody for Rat Amiloride-sensitive sodium channel subunit gamma
Polyclonal Antibody for Rat Amiloride-sensitive sodium channel subunit gamma
Polyclonal Antibody for Rat Amiloride-sensitive sodium channel subunit gamma
Polyclonal Antibody for Rat Amiloride-sensitive sodium channel subunit gamma
Monoclonal Antibody for Rat Amiloride-sensitive sodium channel subunit gamma
Monoclonal Antibody for Rat Amiloride-sensitive sodium channel subunit gamma
Monoclonal Antibody for Rat Amiloride-sensitive sodium channel subunit gamma
Monoclonal Antibody for Rat Amiloride-sensitive sodium channel subunit gamma
Protein for Rat Amiloride-sensitive sodium channel subunit gamma
Protein for Rat Amiloride-sensitive sodium channel subunit gamma
Protein for Rat Amiloride-sensitive sodium channel subunit gamma
Protein for Rat Amiloride-sensitive sodium channel subunit gamma
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley .
tissue :
Distal colon epithelium .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Wistar .
tissue :
Distal colon .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
strain :
Sprague-Dawley .
tissue :
Distal colon .
tissue :
Kidney .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : MUTAGENESIS OF LYS-6 AND LYS-13;UBIQUITINATION
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : PHOSPHORYLATION
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INTERACTION WITH NEDD4