Senp2 ELISA Kit for Rat(Rattus norvegicus) | EIAab.comSenp2 ELISA Kit for Rat(Rattus norvegicus)

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Senp2 (Gene name),

Sentrin-specific protease 2 (Protein name ), SENP2_RAT from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Senp2;

Protein name:

Sentrin-specific protease 2;

Alternative:

Sentrin/SUMO-specific protease SENP2;Axin-associating molecule(Axam);

Organism:

Rat (Rattus norvegicus).

General Annotation

Sub Unit:

Binds to SUMO2 and SUMO3. Interacts with the C-terminal domain of NUP153 via its N-terminus (By similarity). Binds to axin.

Function:

Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.

Subcellular Location:

Nucleus nuclear pore complex Nucleus membrane Peripheral membrane protein Nucleoplasmic side Cytoplasm Cytoplasmic vesicle Cytoplasmic and in cytoplasmic vesicles, together with axin. May shuttle between the nucleus and the cytoplasm.

Protein Attributes:

Sequence length:

588

Sequence:

50:

100:

150:

200:

250:

300:

350:

400:

450:

500:

550:

588:

TCKYADYISR | DKPITFTQHQ | MPLFRKKMVW | EILHQQLL

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

String:

Q9EQE1

Pfam:

PF02902

KEGG:

rno:78973

UniGene:

Rn.9367

SMR:

Q9EQE1

STRING:

10116.ENSRNOP00000002425

Uniprot:

Q9EQE1

FOR

ELISA Kit for Rat Sentrin-specific protease 2

CLIA Kit for Rat Sentrin-specific protease 2

Polyclonal Antibody for Rat Sentrin-specific protease 2

Monoclonal Antibody for Rat Sentrin-specific protease 2

Protein for Rat Sentrin-specific protease 2

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Inhibition of Wnt signaling pathway by a novel Axin-binding protein."
Kadoya T. , Kishida S. , Fukui A. , Hinoi T. , Michiue T. , Asashima M. , Kikuchi A.
J. Biol. Chem.275:37030-37037(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Brain.
2.

"Desumoylation activity of Axam, a novel Axin-binding protein, is involved in downregulation of beta-catenin."
Kadoya T. , Yamamoto H. , Suzuki T. , Yukita A. , Fukui A. , Michiue T. , Asahara T. , Tanaka K. , Asashima M. , Kikuchi A.
Mol. Cell. Biol.22:3803-3819(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;MUTAGENESIS OF CYS-547

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