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Index > Protein center > SESN1(Gene name) > Human
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  • SESN1 (Gene name),
  • Sestrin-1 (Protein name ),  SESN1_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    SESN1(PA26;SEST1);
    Protein name:
    Sestrin-1;
    Alternative:
    p53-regulated protein PA26;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Involved in the reduction of peroxiredoxins. May also be regulator of cellular growth.
    Subcellular Location:
    Nucleus
    Protein Attributes:
    Sequence length:
    492
    Sequence:
    50:
    MRLAAAANEA | YTAPLAVSGL | LGCKQCGGGR | DQDEELGIRI | PRPLGQGPSR | 
    100:
    FIPEKEILQV | GSEDAQMHAL | FADSFAALGR | LDNITLVMVF | HPQYLESFLK | 
    150:
    TQHYLLQMDG | PLPLHYRHYI | GIMAAARHQC | SYLVNLHVND | FLHVGGDPKW | 
    200:
    LNGLENAPQK | LQNLGELNKV | LAHRPWLITK | EHIEGLLKAE | EHSWSLAELV | 
    250:
    HAVVLLTHYH | SLASFTFGCG | ISPEIHCDGG | HTFRPPSVSN | YCICDITNGN | 
    300:
    HSVDEMPVNS | AENVSVSDSF | FEVEALMEKM | RQLQECRDEE | EASQEEMASR | 
    350:
    FEIEKRESMF | VFSSDDEEVT | PARAVSRHFE | DTSYGYKDFS | RHGMHVPTFR | 
    400:
    VQDYCWEDHG | YSLVNRLYPD | VGQLIDEKFH | IAYNLTYNTM | AMHKDVDTSM | 
    450:
    LRRAIWNYIH | CMFGIRYDDY | DYGEINQLLD | RSFKVYIKTV | VCTPEKVTKR | 
    492:
    MYDSFWRQFK | HSEKVHVNLL | LIEARMQAEL | LYALRAITRY | MT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    MIM:
    UniGene:
    Pfam:
    SMR:
    String:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Sestrin-1
    Cat.:
    E0440h
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Human Sestrin-1
    Cat.:
    E0440m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Sestrin-1
    Cat.:
    U0440h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Human Sestrin-1
    Cat.:
    U0440m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Human Sestrin-1
    Cat.:
    P0440Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Human Sestrin-1
    Cat.:
    P0440Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Human Sestrin-1
    Monoclonal Antibody for Human Sestrin-1
    Protein for Human Sestrin-1
    Protein for Human Sestrin-1

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes."
      Velasco-Miguel S. , Buckbinder L. , Jean P. , Gelbert L. , Talbott R. , Laidlaw J. , Seizinger B. , Kley N.
      Oncogene18:127-137(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS T1; T2 AND T3)
    2. 2.
      "PA26 is a candidate gene for heterotaxia in humans: identification of a novel PA26-related gene family in human and mouse."
      Peeters H. , Debeer P. , Bairoch A. , Wilquet V. , Huysmans C. , Parthoens E. , Fryns J.-P. , Gewillig M. , Nakamura Y. , Niikawa N. , Van De Ven W. , Devriendt K.
      Hum. Genet.112:573-580(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA];VARIANT ILE-44;TISSUE SPECIFICITY
    3. 3.
      "The DNA sequence and analysis of human chromosome 6."
      Mungall A.J. , Palmer S.A. , Sims S.K. , Edwards C.A. , Ashurst J.L. , Wilming L. , Jones M.C. , Horton R. , Hunt S.E. , Scott C.E. , Gilbert J.G.R. , Clamp M.E. , Bethel G. , Milne S. , Ainscough R. , Almeida J.P. , Ambrose K.D. , Andrews T.D. , more...
      Nature425:805-811(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    4. 4.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM T1)
      tissue: Lung.
    6. 6.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 309-492
      tissue: Placenta.
    7. 7.
      "Regeneration of peroxiredoxins by p53-regulated sestrins, homologs of bacterial AhpD."
      Budanov A.V. , Sablina A.A. , Feinstein E. , Koonin E.V. , Chumakov P.M.
      Science304:596-600(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
    8. 8.
      "ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage."
      Matsuoka S. , Ballif B.A. , Smogorzewska A. , McDonald E.R. III , Hurov K.E. , Luo J. , Bakalarski C.E. , Zhao Z. , Solimini N. , Lerenthal Y. , Shiloh Y. , Gygi S.P. , Elledge S.J.
      Science316:1160-1166(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-293;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Embryonic kidney.
    9. 9.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-314;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
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