Protein name:
    Sesquipedalian-1 (Ses1) ;
    
    Alternative:
    
    27 kDa inositol polyphosphate phosphatase-interacting protein A (IPIP27A) ;
    
    
 
    Organism:
        
        
        
        
        
        
    
        Human  (Homo sapiens).  
    
 
General Annotation
    Sub Unit:
    Forms homodimers and heterodimers with FAM109B. Interacts with OCRL and INPP5B.
    
 
    Function:
    Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
    
 
    
        
        Subcellular Location:
        
    
     
     
      Early endosome 
      
     
      Recycling endosome 
      
     
      Golgi apparatus  
      trans-Golgi network 
      
     
      Cytoplasmic vesicle  
      clathrin-coated vesicle 
      
    Interaction with OCRL may be crucial for targeting to endosome and to the trans-Golgi network. Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes. 
  
    
 
    
    Protein Attributes:
    
    50:
    MKLNERSLAF |  YATCDAPVDN |  AGFLYKKGGR |  HAAYHRRWFV |  LRGNMLFYFE |  
    
 
    100:
    DAASREPVGV |  IILEGCTVEL |  VEAAEEFAFA |  VRFAGTRART |  YVLAAESQDA |  
    
 
    150:
    MEGWVKALSR |  ASFDYLRLVV |  RELEQQLAAV |  RGGGGMALPQ |  PQPQSLPLPP |  
    
 
    200:
    SLPSALAPVP |  SLPSAPAPVP |  ALPLPRRPSA |  LPPKENGCAV |  WSTEATFRPG |  
    
 
    249:
    PEPPPPPPRR |  RASAPHGPLD |  MAPFARLHEC |  YGQEIRALRG |  QWLSSRVQP
    
 
      Vaild Sequence:
    
 
Related Databases
Uniprot:
 
 
    
        
        ELISA Kit
         
        
        CLIA Kit
         
        
        Polyclonal Antibody
         
        
        Monoclonal Antibody
         
        
        Protein
         
        
     
FOR
    
        
        Rat
         
        
        Mouse
         
        
        Human
         
        
     
    
        Polyclonal Antibody for Human Ses1
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Ses1
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Ses1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Ses1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Ses1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Ses1
        
     
    
    
    
    
    
    
 
 
 
 
 
 
 
 
    R&D Technical Data
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
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    Precision
    
    
    
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        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
        For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
    
    
    
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    Recovery
    
    
    
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    Linearity
    
    
    
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    References
    
    
        
            
        
            
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                              more...   
                             
                        
                        
                        
                            Nat. Genet.36:40-45(2004)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2) 
                    
                    
                    tissue :
                    
Prostate .  
             
         
            
        
            
                2.
                
                    
                        
                            "The finished DNA sequence of human chromosome 12." 
                        
                        
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                              more...   
                             
                        
                        
                        
                            Nature440:346-351(2006)
                         
                        
                        
                        [
PubMed ]
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Europe PMC ]
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                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA] 
                    
                    
                 
             
         
            
        
            
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                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 3);NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 1-80 (ISOFORM 4) 
                    
                    
                    tissue :
                    
Brain .  
             
         
            
        
            
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                        Cited for INTERACTION WITH OCRL AND INPP5B;SUBCELLULAR LOCATION;F&H MOTIF;MUTAGENESIS OF PHE-224 AND HIS-228 
                    
                    
                 
             
         
            
        
            
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                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for FUNCTION;INTERACTION WITH OCRL AND INPP5B;SUBUNIT;SUBCELLULAR LOCATION;MUTAGENESIS OF PHE-224; HIS-228 AND 234-GLU-ILE-235 
                    
                    
                 
             
         
            
        
            
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                        Cited for X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF 223-235 IN COMPLEX WITH OCRL;F&H MOTIF