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Index > Protein center > FAM109B(Gene name) > Human
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  • FAM109B (Gene name),
  • Sesquipedalian-2 (Protein name ),  SESQ2_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Related Databases
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  • Gene name:
    FAM109B;
    Protein name:
    Sesquipedalian-2(Ses2);
    Alternative:
    27 kDa inositol polyphosphate phosphatase interacting protein B(IPIP27B);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Forms homodimers and heterodimers with FAM109A. Interacts with OCRL and INPP5B.
    Function:
    Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the trans-Golgi network and the plasma membrane.
    Subcellular Location:
    Early endosome Recycling endosome Golgi apparatus trans-Golgi network Cytoplasmic vesicle clathrin-coated vesicle Also found on macropinosomes. Not detected in late endosomes, nor in lysosomes.
    Protein Attributes:
    Sequence length:
    259
    Sequence:
    50:
    MKLNERSVAH | YALSDSPADH | MGFLRTWGGP | GTPPTPSGTG | RRCWFVLKGN | 
    100:
    LLFSFESREG | RAPLSLVVLE | GCTVELAEAP | VPEEFAFAIC | FDAPGVRPHL | 
    150:
    LAAEGPAAQE | AWVKVLSRAS | FGYMRLVVRE | LESQLQDARQ | SLALQRRSSW | 
    200:
    KSVASRCKPQ | APNHRAAGLE | NGHCLSKDSS | PVGLVEEAGS | RSAGWGLAEW | 
    250:
    ELQGPASLLL | GKGQSPVSPE | TSCFSTLHDW | YGQEIVELRQ | CWQKRAQGSH | 
    259:
    SKCEEQDRP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Ses2
    ELISA Kit for Human Ses2
    ELISA Kit for Human Ses2
    CLIA Kit for Human Ses2
    CLIA Kit for Human Ses2
    CLIA Kit for Human Ses2
    Polyclonal Antibody for Human Ses2
    Polyclonal Antibody for Human Ses2
    Polyclonal Antibody for Human Ses2
    Monoclonal Antibody for Human Ses2
    Monoclonal Antibody for Human Ses2
    Monoclonal Antibody for Human Ses2
    Protein for Human Ses2
    Protein for Human Ses2
    Protein for Human Ses2

    R&D Technical Data
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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    2. 2.
      "The DNA sequence of human chromosome 22."
      Dunham I. , Hunt A.R. , Collins J.E. , Bruskiewich R. , Beare D.M. , Clamp M. , Smink L.J. , Ainscough R. , Almeida J.P. , Babbage A.K. , Bagguley C. , Bailey J. , Barlow K.F. , Bates K.N. , Beasley O.P. , Bird C.P. , Blakey S.E. , Bridgeman A.M. , more...
      Nature402:489-495(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA];VARIANT GLY-188
      tissue: Colon.
    4. 4.
      "Two closely related endocytic proteins that share a common OCRL-binding motif with APPL1."
      Swan L.E. , Tomasini L. , Pirruccello M. , Lunardi J. , De Camilli P.
      Proc. Natl. Acad. Sci. U.S.A.107:3511-3516(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH OCRL;F&H MOTIF;SUBCELLULAR LOCATION
    5. 5.
      "The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway."
      Noakes C.J. , Lee G. , Lowe M.
      Mol. Biol. Cell22:606-623(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION;INTERACTION WITH OCRL AND INPP5B;SUBUNIT;SUBCELLULAR LOCATION;MUTAGENESIS OF PHE-224; HIS-228 AND 234-GLU-ILE-235
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