Gene name:
SF3A1 (SAP114) ;
Protein name:
Splicing factor 3A subunit 1 ;
Alternative:
Spliceosome-associated protein 114 (SAP 114) ;SF3a120 ;
Organism:
Human (Homo sapiens).
General Annotation
Sub Unit:
Identified in the spliceosome C complex. Component of splicing factor SF3A which is composed of three subunits; SF3A3/SAP61, SF3A2/SAP62, SF3A1/SAP114. SF3A associates with the splicing factor SF3B and a 12S RNA unit to form the U2 small nuclear ribonucleoproteins complex (U2 snRNP). Interacts with SF3A3.
Function:
Subunit of the splicing factor SF3A required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. May also be involved in the assembly of the 'E' complex.
Subcellular Location:
Nucleus
Protein Attributes:
50:
MPAGPVQAVP | PPPPVPTEPK | QPTEEEASSK | EDSAPSKPVV | GIIYPPPEVR |
100:
NIVDKTASFV | ARNGPEFEAR | IRQNEINNPK | FNFLNPNDPY | HAYYRHKVSE |
150:
FKEGKAQEPS | AAIPKVMQQQ | QQTTQQQLPQ | KVQAQVIQET | IVPKEPPPEF |
200:
EFIADPPSIS | AFDLDVVKLT | AQFVARNGRQ | FLTQLMQKEQ | RNYQFDFLRP |
250:
QHSLFNYFTK | LVEQYTKILI | PPKGLFSKLK | KEAENPREVL | DQVCYRVEWA |
300:
KFQERERKKE | EEEKEKERVA | YAQIDWHDFV | VVETVDFQPN | EQGNFPPPTT |
350:
PEELGARILI | QERYEKFGES | EEVEMEVESD | EEDDKQEKAE | EPPSQLDQDT |
400:
QVQDMDEGSD | DEEEGQKVPP | PPETPMPPPL | PPTPDQVIVR | KDYDPKASKP |
450:
LPPAPAPDEY | LVSPITGEKI | PASKMQEHMR | IGLLDPRWLE | QRDRSIREKQ |
500:
SDDEVYAPGL | DIESSLKQLA | ERRTDIFGVE | ETAIGKKIGE | EEIQKPEEKV |
550:
TWDGHSGSMA | RTQQAAQANI | TLQEQIEAIH | KAKGLVPEDD | TKEKIGPSKP |
600:
NEIPQQPPPP | SSATNIPSSA | PPITSVPRPP | TMPPPVRTTV | VSAVPVMPRP |
650:
PMASVVRLPP | GSVIAPMPPI | IHAPRINVVP | MPPSAPPIMA | PRPPPMIVPT |
700:
AFVPAPPVAP | VPAPAPMPPV | HPPPPMEDEP | TSKKLKTEDS | LMPEEEFLRR |
750:
NKGPVSIKVQ | VPNMQDKTEW | KLNGQVLVFT | LPLTDQVSVI | KVKIHEATGM |
793:
PAGKQKLQYE | GIFIKDSNSL | AYYNMANGAV | IHLALKERGG | RKK
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Bovine
Mouse
ELISA Kit for Human Splicing factor 3A subunit 1
ELISA Kit for Human Splicing factor 3A subunit 1
ELISA Kit for Human Splicing factor 3A subunit 1
CLIA Kit for Human Splicing factor 3A subunit 1
CLIA Kit for Human Splicing factor 3A subunit 1
CLIA Kit for Human Splicing factor 3A subunit 1
Polyclonal Antibody for Human Splicing factor 3A subunit 1
Polyclonal Antibody for Human Splicing factor 3A subunit 1
Polyclonal Antibody for Human Splicing factor 3A subunit 1
Monoclonal Antibody for Human Splicing factor 3A subunit 1
Monoclonal Antibody for Human Splicing factor 3A subunit 1
Monoclonal Antibody for Human Splicing factor 3A subunit 1
Protein for Human Splicing factor 3A subunit 1
Protein for Human Splicing factor 3A subunit 1
Protein for Human Splicing factor 3A subunit 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
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[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
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