FRZB ELISA Kit for Bovine(Bos taurus) | EIAab.comFRZB ELISA Kit for Bovine(Bos taurus)

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Index > Protein center > FRZB(Gene name) > Bovine

FRZB (Gene name),

Secreted frizzled-related protein 3 (Protein name ), SFRP3_BOVIN from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

FRZB(FRZB1;SFRP3);

Protein name:

Secreted frizzled-related protein 3(sFRP-3);

Alternative:

FrzB-1;Frizzled-related protein 1;

Organism:

Bovine (Bos taurus).

General Annotation

Sub Unit:

N/A

Function:

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appears to be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bone development.

Subcellular Location:

Secreted

Protein Attributes:

Sequence length:

325

Sequence:

50:

100:

150:

200:

250:

300:

325:

SDSSHSDSTQ | SQKPGRNSNS | RQARN

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

bta:281170

Pfam:

PF01392

UniGene:

Bt.121

SMR:

Q95117

String:

Q95117

Uniprot:

Q95117

FOR

ELISA Kit for Bovine sFRP-3

CLIA Kit for Bovine sFRP-3

Polyclonal Antibody for Bovine sFRP-3

Monoclonal Antibody for Bovine sFRP-3

Protein for Bovine sFRP-3

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Primary structure and tissue distribution of FRZB, a novel protein related to Drosophila frizzled, suggest a role in skeletal morphogenesis."
Hoang B. , Moos M. Jr. , Vukicevic S. , Luyten F.P.
J. Biol. Chem.271:26131-26137(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
tissue: Cartilage.
2.

NIH - Mammalian Gene Collection (MGC) project
Submitted (2006-01) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: Hereford.
tissue: Kidney.
3.

"The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling."
Lin K. , Wang S. , Julius M.A. , Kitajewski J. , Moos M. Jr. , Luyten F.P.
Proc. Natl. Acad. Sci. U.S.A.94:11196-11200(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION OF THE FZ DOMAIN WITH WNT PROTEINS

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