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Index > Protein center > Sfrp4(Gene name) > Mouse
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  • Sfrp4 (Gene name),
  • Secreted frizzled-related sequence protein 4 (Protein name ),  SFRP4_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Sfrp4;
    Protein name:
    Secreted frizzled-related sequence protein 4(FRP-4;sFRP-4);
    Alternative:

    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling. Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
    Subcellular Location:
    Secreted
    Protein Attributes:
    Sequence length:
    351
    Sequence:
    50:
    MLRSILVALC | LWLRLALGVR | GAPCEAVRIP | MCRHMPWNIT | RMPNHLHHST | 
    100:
    QENAILAIEQ | YEELVDVNCS | SVLRFFLCAM | YAPICTLEFL | HDPIKPCKSV | 
    150:
    CQRARDDCEP | LMKMYNHSWP | ESLACDELPV | YDRGVCISPE | AIVTDLPEDV | 
    200:
    KWIDITPDMM | VQERSFDADC | KRLSPDRCKC | KKVKPTLATY | LSKNYSYVIH | 
    250:
    AKIKAVQRSG | CNEVTTVVDV | KEIFKSLSPI | PRTQVPLITN | SSCQCPHILP | 
    300:
    HQDVLIMCYE | WRSRMMLLEN | CLVEKWRDQL | SRRSIQWEER | LQEQQRTIQD | 
    350:
    KKQIASRTSR | TSRSNPPKSK | GRPPAPKPAS | PKKNIKARSA | PKKSNLKKSA | 
    351:
    S
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    UniGene:
    Pfam:
    SMR:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse FRP-4
    Cat.:
    E1650m
    Price:
    Please sign in first.
    MSDS:
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    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse FRP-4
    Cat.:
    E1650h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    ELISA Kit for Mouse FRP-4
    Cat.:
    E1650r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse FRP-4
    Cat.:
    U1650h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse FRP-4
    Cat.:
    U1650m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse FRP-4
    Cat.:
    U1650r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse FRP-4
    Cat.:
    P1650Rb-h
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse FRP-4
    Cat.:
    P1650Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse FRP-4
    Cat.:
    P1650Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse FRP-4
    Monoclonal Antibody for Mouse FRP-4
    Monoclonal Antibody for Mouse FRP-4
    Protein for Mouse FRP-4
    Protein for Mouse FRP-4
    Protein for Mouse FRP-4

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    Precision
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    Linearity
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    References
    1. 1.
      "Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium."
      Chang J.T. , Esumi N. , Moore K. , Li Y. , Zhang S. , Chew C. , Goodman B. , Rattner A. , Moody S. , Stetten G. , Campochiaro P.A. , Zack D.J.
      Hum. Mol. Genet.8:575-583(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "The transcriptional landscape of the mammalian genome."
      Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
      Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Retina.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6J.
      tissue: Mammary gland.
    4. 4.
      "A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors."
      Rattner A. , Hsieh J.-C. , Smallwood P.M. , Gilbert D.J. , Copeland N.G. , Jenkins N.A. , Nathans J.
      Proc. Natl. Acad. Sci. U.S.A.94:2859-2863(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-161
      strain: C57BL/6J.
      tissue: Embryonic eye.
    5. 5.
      "Transcriptional activity of the promoter region of rat frizzled-related protein gene."
      Yam J.W.P. , Chan K.W. , Wong V.K.W. , Hsiao W.L.W.
      Biochem. Biophys. Res. Commun.286:94-100(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-148
      strain: 129/SvCp.
    6. 6.
      "Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family."
      Leimeister C. , Bach A. , Gessler M.
      Mech. Dev.75:29-42(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: DEVELOPMENTAL STAGE
    7. 7.
      "Expression and localization of secreted frizzled-related protein-4 in the rodent ovary: evidence for selective up-regulation in luteinized granulosa cells."
      Hsieh M. , Mulders S.M. , Friis R.R. , Dharmarajan A. , Richards J.S.
      Endocrinology144:4597-4606(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY;INDUCTION
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