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Index > Protein center > SGTA(Gene name) > Human
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  • SGTA (Gene name),
  • Small glutamine-rich tetratricopeptide repeat-containing protein alpha (Protein name ),  SGTA_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    SGTA(SGT;SGT1);
    Protein name:
    Small glutamine-rich tetratricopeptide repeat-containing protein alpha;
    Alternative:
    Vpu-binding protein(UBP);Alpha-SGT;
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    Homooligomerize (By similarity). Interacts with NS1 from parvovirus H-1, with Vpu and Gag from HIV-1. Interacts with SARS-CoV accessory protein 7a. Interacts with DNAJC5 and DNAJC5B.
    Function:
    Co-chaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    313
    Sequence:
    50:
    MDNKKRLAYA | IIQFLHDQLR | HGGLSSDAQE | SLEVAIQCLE | TAFGVTVEDS | 
    100:
    DLALPQTLPE | IFEAAATGKE | MPQDLRSPAR | TPPSEEDSAE | AERLKTEGNE | 
    150:
    QMKVENFEAA | VHFYGKAIEL | NPANAVYFCN | RAAAYSKLGN | YAGAVQDCER | 
    200:
    AICIDPAYSK | AYGRMGLALS | SLNKHVEAVA | YYKKALELDP | DNETYKSNLK | 
    250:
    IAELKLREAP | SPTGGVGSFD | IAGLLNNPGF | MSMASNLMNN | PQIQQLMSGM | 
    300:
    ISGGNNPLGT | PGTSPSQNDL | ASLIQAGQQF | AQQMQQQNPE | LIEQLRSQIR | 
    313:
    SRTPSASNDD | QQE
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    String:
    Pfam:
    MIM:
    SMR:
    UniGene:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    ELISA Kit for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    ELISA Kit for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    ELISA Kit for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    CLIA Kit for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    CLIA Kit for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    CLIA Kit for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    CLIA Kit for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    Polyclonal Antibody for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    Polyclonal Antibody for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    Polyclonal Antibody for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    Polyclonal Antibody for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    Monoclonal Antibody for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    Monoclonal Antibody for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    Monoclonal Antibody for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    Monoclonal Antibody for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    Protein for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    Protein for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    Protein for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha
    Protein for Human Small glutamine-rich tetratricopeptide repeat-containing protein alpha

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Isolation and characterization of human SGT and identification of homologues in Saccharomyces cerevisiae and Caenorhabditis elegans."
      Kordes E. , Savelyeva L. , Schwab M. , Rommelaere J. , Jauniaux J.-C. , Cziepluch C.
      Genomics52:90-94(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Specific interaction of the 70-kDa heat shock cognate protein with the tetratricopeptide repeats."
      Liu F.H. , Wu S.J. , Hu S.M. , Hsiao C.D. , Wang C.
      J. Biol. Chem.274:34425-34432(1999) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Functional interaction of human immunodeficiency virus type 1 Vpu and Gag with a novel member of the tetratricopeptide repeat protein family."
      Callahan M.A. , Handley M.A. , Lee Y.H. , Talbot K.J. , Harper J.W. , Panganiban A.T.
      J. Virol.72:5189-5197(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    4. 4.
      Tobaben S. , Stahl B.
      Submitted (2001-04) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Uterus.
    6. 6.
      "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
      Halleck A. , Ebert L. , Mkoundinya M. , Schick M. , Eisenstein S. , Neubert P. , Kstrang K. , Schatten R. , Shen B. , Henze S. , Mar W. , Korn B. , Zuo D. , Hu Y. , LaBaer J.
      Submitted (2004-06) to the EMBL/GenBank/DDBJ databases
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    7. 7.
      "The DNA sequence and biology of human chromosome 19."
      Grimwood J. , Gordon L.A. , Olsen A.S. , Terry A. , Schmutz J. , Lamerdin J.E. , Hellsten U. , Goodstein D. , Couronne O. , Tran-Gyamfi M. , Aerts A. , Altherr M. , Ashworth L. , Bajorek E. , Black S. , Branscomb E. , Caenepeel S. , Carrano A.V. , more...
      Nature428:529-535(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    8. 8.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    9. 9.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      tissue: Lung.
      tissue: Muscle.
      tissue: Uterus.
    10. 10.
      Lubec G. , Chen W.-Q. , Sun Y.
      Submitted (2008-12) to the UniProtKB
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 138-160; 165-174 AND 185-196
      tissue: Fetal brain cortex.
    11. 11.
      "Severe acute respiratory syndrome coronavirus protein 7a interacts with hSGT."
      Fielding B.C. , Gunalan V. , Tan T.H.P. , Chou C.-F. , Shen S. , Khan S. , Lim S.G. , Hong W. , Tan Y.-J.
      Biochem. Biophys. Res. Commun.343:1201-1208(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH SARS-COV ACCESSORY PROTEIN 7A
    12. 12.
      "A probability-based approach for high-throughput protein phosphorylation analysis and site localization."
      Beausoleil S.A. , Villen J. , Gerber S.A. , Rush J. , Gygi S.P.
      Nat. Biotechnol.24:1285-1292(2006) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-305;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    13. 13.
      "Cysteine-string protein isoform beta (Cspbeta) is targeted to the trans-Golgi network as a non-palmitoylated CSP in clonal beta-cells."
      Boal F. , Le Pevelen S. , Cziepluch C. , Scotti P. , Lang J.
      Biochim. Biophys. Acta1773:109-119(2007) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH DNAJC5 AND DNAJC5B
    14. 14.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-77; THR-81; SER-301; THR-303 AND SER-305;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    15. 15.
      "Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions."
      Mayya V. , Lundgren D.H. , Hwang S.-I. , Rezaul K. , Wu L. , Eng J.K. , Rodionov V. , Han D.K.
      Sci. Signal.2:RA46-RA46(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-77; THR-81 AND SER-305;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Leukemic T-cell.
    16. 16.
      "Lysine acetylation targets protein complexes and co-regulates major cellular functions."
      Choudhary C. , Kumar C. , Gnad F. , Nielsen M.L. , Rehman M. , Walther T.C. , Olsen J.V. , Mann M.
      Science325:834-840(2009) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT LYS-137;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    17. 17.
      "Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis."
      Olsen J.V. , Vermeulen M. , Santamaria A. , Kumar C. , Miller M.L. , Jensen L.J. , Gnad F. , Cox J. , Jensen T.S. , Nigg E.A. , Brunak S. , Mann M.
      Sci. Signal.3:RA3-RA3(2010) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-303;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
      tissue: Cervix carcinoma.
    18. 18.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    19. 19.
      "System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation."
      Rigbolt K.T. , Prokhorova T.A. , Akimov V. , Henningsen J. , Johansen P.T. , Kratchmarova I. , Kassem M. , Mann M. , Olsen J.V. , Blagoev B.
      Sci. Signal.4:RS3-RS3(2011) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-301 AND SER-305;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
    20. 20.
      "Structural and functional characterization of human SGT and its interaction with Vpu of the human immunodeficiency virus type 1."
      Dutta S. , Tan Y.J.
      Biochemistry47:10123-10131(2008) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 84-210;SUBUNIT;FUNCTION
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