Shank1 ELISA Kit for Mouse(Mus musculus) | EIAab.comShank1 ELISA Kit for Mouse(Mus musculus)

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Index > Protein center > Shank1(Gene name) > Mouse

Shank1 (Gene name),

SH3 and multiple ankyrin repeat domains protein 1 (Protein name ), SHAN1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Shank1;

Protein name:

SH3 and multiple ankyrin repeat domains protein 1(Shank1);

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

May homomultimerize via its SAM domain. Interacts with the C-terminus of SSTR2 via the PDZ domain. Interacts with SHARPIN, SPTAN1, HOMER1 and DLGAP1/GKAP. Part of a complex with DLG4/PSD-95 and DLGAP1/GKAP. Interacts with BAIAP2. Interacts with IGSF9.

Function:

Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction. Overexpression promotes maturation of dendritic spines and the enlargement of spine heads via its ability to recruit Homer to postsynaptic sites, and enhances presynaptic function.

Subcellular Location:

Cytoplasm Cell junction synapse Cell junction synapse postsynaptic cell membrane postsynaptic density Postsynaptic density of neuronal cells. Colocalizes with alpha-latrotoxin receptor 1.

Protein Attributes:

Sequence length:

2167

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2167:

VGHRMNIDRA | LKFFLER

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

SMR:

D3YZU1

KEGG:

mmu:243961

UniGene:

Mm.360368

Pfam:

PF12796

Uniprot:

D3YZU1

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ELISA Kit for Mouse Shank1

Cat.:

E14502r

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Manual:

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MSDS:

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Packing:

96T

Range:

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ELISA Kit for Mouse Shank1

Cat.:

E14502m

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MSDS:

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Packing:

96T

ELISA Kit for Mouse Shank1

Cat.:

E14502h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Shank1

Cat.:

U14502m

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Shank1

Cat.:

U14502h

Price:

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MSDS:

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Packing:

96T

CLIA Kit for Mouse Shank1

Cat.:

U14502r

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse Shank1

Cat.:

P14502Rb-r

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Shank1

Cat.:

P14502Rb-h

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse Shank1

Cat.:

P14502Rb-m

Price:

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse Shank1

Protein for Mouse Shank1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"Lineage-specific biology revealed by a finished genome assembly of the mouse."
Church D.M. , Goodstadt L. , Hillier L.W. , Zody M.C. , Goldstein S. , She X. , Bult C.J. , Agarwala R. , Cherry J.L. , DiCuccio M. , Hlavina W. , Kapustin Y. , Meric P. , Maglott D. , Birtle Z. , Marques A.C. , Graves T. , Zhou S. , more...
PLoS Biol.7:E1000112-E1000112(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
strain: C57BL/6J.
2.

"Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta."
Thuret S. , Bhatt L. , O'Leary D.D. , Simon H.H.
Mol. Cell. Neurosci.25:394-405(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 854-939
3.

"Comprehensive identification of phosphorylation sites in postsynaptic density preparations."
Trinidad J.C. , Specht C.G. , Thalhammer A. , Schoepfer R. , Burlingame A.L.
Mol. Cell. Proteomics5:914-922(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain.
4.

"Large-scale identification and evolution indexing of tyrosine phosphorylation sites from murine brain."
Ballif B.A. , Carey G.R. , Sunyaev S.R. , Gygi S.P.
J. Proteome Res.7:311-318(2008) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT TYR-186;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Brain.
5.

"Shank3 mutant mice display autistic-like behaviours and striatal dysfunction."
Peca J. , Feliciano C. , Ting J.T. , Wang W. , Wells M.F. , Venkatraman T.N. , Lascola C.D. , Fu Z. , Feng G.
Nature472:437-442(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY

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