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Index > Protein center > Shc2(Gene name) > Rat
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  • Shc2 (Gene name),
  • SHC-transforming protein 2 (Protein name ),  SHC2_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    Shc2(Sck);
    Protein name:
    SHC-transforming protein 2;
    Alternative:
    SH2 domain protein C2;Protein Sck;Src homology 2 domain-containing-transforming protein C2;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    Interacts with the Trk receptors in a phosphotyrosine-dependent manner and MEGF12. Once activated, binds to GRB2.
    Function:
    Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
    Subcellular Location:
    N/A
    Protein Attributes:
    Sequence length:
    573
    Sequence:
    50:
    MTQGPGGRAA | PEPEAPTTFC | ALLPRMPQWK | FAAPGSFLGR | GPAAARVAGA | 
    100:
    AEAQPEPGVP | ALAAVLGACE | PRCAAPCPLP | ALGRCRGSGS | RGARGTPDVA | 
    150:
    DEWVRKGGFI | HKPAHGWLHP | DARVLGPGVS | YIVRYMGCIE | VLRSMRSLDF | 
    200:
    NTRTQVTREA | INRLHEAVPG | VRGSWKKKAP | NKALASILGK | SNLRFAGMSI | 
    250:
    SVNISVDGLN | LSVPATRQII | ANHHMQSISF | ASGGDTDMTD | YVAYVAKDPI | 
    300:
    NQRACHILEC | CEGLAQSVIS | TVGQAFELRF | KQYLHSPPKA | VVPPERLTGL | 
    350:
    EESAWGDGEV | TADHDYYNSI | PGKEPPLGGL | VDSRLAVTQP | CALTTLGGLG | 
    400:
    QGLSPAWRDV | RGLPWDMGPS | GAVPPGDGYV | QADARGPHDY | EEHLYVNTQG | 
    450:
    LDALELEDTS | ETPLQPEDSP | KKDLFDMRPF | EDALKLHECS | VAAGITAASL | 
    500:
    PLEDQWPSPP | TRRAPIAPTE | EQLRQEPWYH | GRMSRRAAEK | LLRADGDFLV | 
    550:
    RDSITNPGQY | VLTGMHAGQP | KHLLLVDPEG | VVRTKDVLFE | SISHLIDYHL | 
    573:
    KNGLPIVAAE | SELHLRGVVS | REP
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    Pfam:
    String:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Rat SHC-transforming protein 2
    ELISA Kit for Rat SHC-transforming protein 2
    ELISA Kit for Rat SHC-transforming protein 2
    CLIA Kit for Rat SHC-transforming protein 2
    CLIA Kit for Rat SHC-transforming protein 2
    CLIA Kit for Rat SHC-transforming protein 2
    Polyclonal Antibody for Rat SHC-transforming protein 2
    Polyclonal Antibody for Rat SHC-transforming protein 2
    Polyclonal Antibody for Rat SHC-transforming protein 2
    Monoclonal Antibody for Rat SHC-transforming protein 2
    Monoclonal Antibody for Rat SHC-transforming protein 2
    Monoclonal Antibody for Rat SHC-transforming protein 2
    Protein for Rat SHC-transforming protein 2
    Protein for Rat SHC-transforming protein 2
    Protein for Rat SHC-transforming protein 2

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Genome sequence of the Brown Norway rat yields insights into mammalian evolution."
      Gibbs R.A. , Weinstock G.M. , Metzker M.L. , Muzny D.M. , Sodergren E.J. , Scherer S. , Scott G. , Steffen D. , Worley K.C. , Burch P.E. , Okwuonu G. , Hines S. , Lewis L. , Deramo C. , Delgado O. , Dugan-Rocha S. , Miner G. , Morgan M. , more...
      Nature428:493-521(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
      strain: Brown Norway.
    2. 2.
      "N-Shc and Sck, two neuronally expressed Shc adapter homologs. Their differential regional expression in the brain and roles in neurotrophin and Src signaling."
      Nakamura T. , Muraoka S. , Sanokawa R. , Mori N.
      J. Biol. Chem.273:6960-6967(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 97-573
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