SHC4 ELISA Kit for Human(Homo sapiens) | EIAab.comSHC4 ELISA Kit for Human(Homo sapiens) | EIAab.com

Language:

[Sign in] [Register]

Search Protein-oriented Product center.

For antibodies, ELISA/CLIA, proteins... Product center

Tips

Index > Protein center > SHC4(Gene name) > Human

Add your favorite

SHC4 (Gene name),

SHC-transforming protein 4 (Protein name ), SHC4_HUMAN from NCBI database.

top

Come back to page head.

|

General Annotation

|

Antigen Annotation

|

3D

|

Predicted Eptitope

|

Vaild Sequence

|

Related Databases

|

Feedback

Gene name:

SHC4(UNQ6438/PRO21364;SHCD);

Protein name:

SHC-transforming protein 4;

Alternative:

SHC-transforming protein D(hShcD);Rai-like protein(RaLP);Src homology 2 domain-containing-transforming protein C4(SH2 domain protein C4);

Organism:

Human (Homo sapiens).

General Annotation

Sub Unit:

Interacts (via PID domain) with phosphorylated MUSK (via NPXY motif); undergoes tyrosine phosphorylation downstream of activated MUSK. Interacts with GRB2; the interaction is dependent of Tyr-424 phosphorylation and increased by EGF.

Function:

Activates both Ras-dependent and Ras-independent migratory pathways in melanomas. Contributes to the early phases of agrin-induced tyrosine phosphorylation of CHRNB1.

Subcellular Location:

Cell junction synapse postsynaptic cell membrane Colocalized with MUSK at the neuromuscular junction.

Protein Attributes:

Sequence length:

630

Sequence:

50:

MRERGQDSLA | GLVLYVGLFG | HPGMLHRAKY | SRFRNESITS | LDEGSSGGSV |

100:

GNKGSPQPPH | PALAPHLPTE | DATLPSQESP | TPLCTLIPRM | ASMKLANPAT |

150:

LLSLKNFCLG | TKEVPRLKLQ | ESRDPGSSGP | SSPETSLSRS | GTAPPPQQDL |

200:

VGHRATALTP | DSCPLPGPGE | PTLRSRQDRH | FLQHLLGMGM | NYCVRYMGCV |

250:

EVLQSMRSLD | FGMRTQVTRE | AISRLCEAVP | GANGAIKKRK | PPVKFLSTVL |

300:

GKSNLQFSGM | NIKLTISTCS | LTLMNLDNQQ | IIANHHMQSI | SFASGGDPDT |

350:

TDYVAYVAKD | PVNQRACHIL | ECHNGMAQDV | ISTIGQAFEL | RFKQYLKNPS |

400:

LNTSCESEEV | HIDSHAEERE | DHEYYNEIPG | KQPPVGGVSD | MRIKVQATEQ |

450:

MAYCPIQCEK | LCYLPGNSKC | SSVYENCLEQ | SRAIGNVHPR | GVQSQRDTSL |

500:

LKHTCRVDLF | DDPCYINTQA | LQSTPGSAGN | QRSAQPLGSP | WHCGKAPETV |

550:

QPGATAQPAS | SHSLPHIKQQ | LWSEECYHGK | LSRKAAESLL | VKDGDFLVRE |

600:

SATSPGQYVL | SGLQGGQAKH | LLLVDPEGKV | RTKDHVFDNV | GHLIRYHMDN |

630:

SLPIISSGSE | VSLKQPVRKD | NNPALLHSNK |

3D Structure:

N/A

Predicted Eptitope:

Please Sign in.

Vaild Sequence:

Please Sign in.

Related Databases

KEGG:

STRING:

9606.ENSP00000329668

SMR:

Pfam:

String:

UniGene:

Uniprot:

FOR

ELISA Kit for Human SHC-transforming protein 4

ELISA Kit for Human SHC-transforming protein 4

CLIA Kit for Human SHC-transforming protein 4

CLIA Kit for Human SHC-transforming protein 4

Polyclonal Antibody for Human SHC-transforming protein 4

Polyclonal Antibody for Human SHC-transforming protein 4

Monoclonal Antibody for Human SHC-transforming protein 4

Monoclonal Antibody for Human SHC-transforming protein 4

Protein for Human SHC-transforming protein 4

Protein for Human SHC-transforming protein 4

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Linearity

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

References

1.

"RaLP, a new member of the Src homology and collagen family, regulates cell migration and tumor growth of metastatic melanomas."
Fagiani E. , Giardina G. , Luzi L. , Cesaroni M. , Quarto M. , Capra M. , Germano G. , Bono M. , Capillo M. , Pelicci P. , Lanfrancone L.
Cancer Res.67:3064-3073(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1);FUNCTION;TISSUE SPECIFICITY
2.

"The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment."
Clark H.F. , Gurney A.L. , Abaya E. , Baker K. , Baldwin D.T. , Brush J. , Chen J. , Chow B. , Chui C. , Crowley C. , Currell B. , Deuel B. , Dowd P. , Eaton D. , Foster J.S. , Grimaldi C. , Gu Q. , Hass P.E. , more...
Genome Res.13:2265-2270(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2)
3.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1);VARIANTS ASP-52; GLU-244 AND GLY-447
tissue: Testis.
4.

"Analysis of a Shc family adaptor protein, ShcD/Shc4, that associates with muscle-specific kinase."
Jones N. , Hardy W.R. , Friese M.B. , Jorgensen C. , Smith M.J. , Woody N.M. , Burden S.J. , Pawson T.
Mol. Cell. Biol.27:4759-4773(2007) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH MUSK AND GRB2;PHOSPHORYLATION AT TYR-424;MUTAGENESIS OF ARG-315; 374-TYR-TYR-375; TYR-403; TYR-413; TYR-424; TYR-465 AND ARG-549

Product Feedback Wall

Hot Genes: Atf2 ASPRO ACE ALCAM C19orf80 Trap1a Gdf5

Top Searches: Ubiquitin-protein ligase metalloproteinase Ubiquitin ELISA Alpha Tumor necrosis Asprosin TRAP1A

Why choose EIAAB: Our products have been quoted by many publications in famous journals such as Cell; Cell Metabolism; Hepatology; Biomaterials.more

Further Information: About us Protein center Bank account Distributors Terms & Conditions Career eiaab.com.cn

Copyright & copy www.eiaab.com2006-2016 All Rights Reserved EIAab Email:eiaab@eiaab.com

鄂ICP备10015095号-1

鄂公网安备 42018502005535号