Gene name:
    ST3GAL1 (SIAT4;SIAT4A) ;
    
 
    Protein name:
    CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (Alpha 2,3-ST 1;Beta-galactoside alpha-2,3-sialyltransferase 1) ;
    
    Alternative:
    
    Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase ;Gal-NAc6S ;ST3Gal I (ST3GalI) ;SIATFL ;ST3O ;ST3GalA.1 ;Sialyltransferase 4A (SIAT4-A) ;
    
    
 
    Organism:
        
        
        
        
        
        
    
        Human  (Homo sapiens).  
    
 
General Annotation
    Function:
    It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O-linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values.
    
 
    
        
        Subcellular Location:
        
    
     
     
      Golgi apparatus  
      Golgi stack membrane  
      Single-pass type II membrane protein 
      
     
      Secreted 
      
    Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid. 
  
    
 
    
    Protein Attributes:
    
    50:
    MVTLRKRTLK |  VLTFLVLFIF |  LTSFFLNYSH |  TMVATTWFPK |  QMVLELSENL |  
    
 
    100:
    KRLIKHRPCT |  CTHCIGQRKL |  SAWFDERFNQ |  TMQPLLTAQN |  ALLEDDTYRW |  
    
 
    150:
    WLRLQREKKP |  NNLNDTIKEL |  FRVVPGNVDP |  MLEKRSVGCR |  RCAVVGNSGN |  
    
 
    200:
    LRESSYGPEI |  DSHDFVLRMN |  KAPTAGFEAD |  VGTKTTHHLV |  YPESFRELGD |  
    
 
    250:
    NVSMILVPFK |  TIDLEWVVSA |  ITTGTISHTY |  IPVPAKIRVK |  QDKILIYHPA |  
    
 
    300:
    FIKYVFDNWL |  QGHGRYPSTG |  ILSVIFSMHV |  CDEVDLYGFG |  ADSKGNWHHY |  
    
 
    340:
    WENNPSAGAF |  RKTGVHDADF |  ESNVTATLAS |  INKIRIFKGR |  
    
 
      Vaild Sequence:
    
 
Related Databases
Uniprot:
 
 
    
        
        ELISA Kit
         
        
        CLIA Kit
         
        
        Polyclonal Antibody
         
        
        Monoclonal Antibody
         
        
        Protein
         
        
     
FOR
    
        
        Chicken
         
        
        Mouse
         
        
        Pig
         
        
        Human
         
        
     
    
        ELISA Kit for Human Alpha 2,3-ST 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human Alpha 2,3-ST 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human Alpha 2,3-ST 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        ELISA Kit for Human Alpha 2,3-ST 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human Alpha 2,3-ST 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human Alpha 2,3-ST 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human Alpha 2,3-ST 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        CLIA Kit for Human Alpha 2,3-ST 1
        
     
    
    
    
    
   
    
    
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Alpha 2,3-ST 1
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Alpha 2,3-ST 1
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Alpha 2,3-ST 1
        
     
    
    
    
    
    
    
 
    
        Polyclonal Antibody for Human Alpha 2,3-ST 1
        
     
    
    
    
    
   
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Alpha 2,3-ST 1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Alpha 2,3-ST 1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Alpha 2,3-ST 1
        
     
    
    
    
    
    
    
 
    
        Monoclonal Antibody for Human Alpha 2,3-ST 1
        
     
    
    
    
    
    
    
 
    
        Protein for Human Alpha 2,3-ST 1
        
     
    
    
    
    
    
    
 
    
        Protein for Human Alpha 2,3-ST 1
        
     
    
    
    
    
    
    
 
    
        Protein for Human Alpha 2,3-ST 1
        
     
    
    
    
    
    
    
 
    
        Protein for Human Alpha 2,3-ST 1
        
     
    
    
    
    
    
    
 
 
 
 
 
 
 
 
    R&D Technical Data
    
    
    
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    Precision
    
    
    
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    Recovery
    
    
    
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    Linearity
    
    
    
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    References
    
    
        
            
        
            
                1.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] 
                    
                    
                    tissue :
                    
Placenta .  
             
         
            
        
            
                2.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] 
                    
                    
                    tissue :
                    
Submandibular gland .  
             
         
            
        
            
                3.
                
                    
                        
                            "Molecular cloning and expression of Galbeta1,3GalNAc alpha2, 3-sialyltransferase from human fetal liver." 
                        
                        
                            Shang J. 
                        ,
                            
Qiu R. 
                        ,
                            
Wang J. 
                        ,
                            
Liu J. 
                        ,
                            
Zhou R. 
                        ,
                            
Ding H. 
                        ,
                            
Yang S. 
                        ,
                            
Zhang S. 
                        ,
                            
Jin C. 
                        
                        
                        
                        
                            Eur. J. Biochem.265:580-588(1999)
                         
                        
                        
                        [
PubMed ]
                        [
Europe PMC ]
                        [
Abstract ]
                        
                    
 
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [MRNA] 
                    
                    
                    tissue :
                    
Fetal liver .  
             
         
            
        
            
                4.
                
                    
                    
                        [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
                        Cited for NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] 
                    
                    
                    tissue :
                    
Skin .