Gene name:
ST3GAL1 (SIAT4;SIAT4A) ;
Protein name:
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (Alpha 2,3-ST 1;Beta-galactoside alpha-2,3-sialyltransferase 1) ;
Alternative:
Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase ;Gal-NAc6S ;ST3Gal I (ST3GalI) ;SIATFL ;ST3O ;ST3GalA.1 ;Sialyltransferase 4A (SIAT4-A) ;
Organism:
Human (Homo sapiens).
General Annotation
Function:
It may be responsible for the synthesis of the sequence NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- found on sugar chains O-linked to Thr or Ser and also as a terminal sequence on certain gangliosides. SIAT4A and SIAT4B sialylate the same acceptor substrates but exhibit different Km values.
Subcellular Location:
Golgi apparatus
Golgi stack membrane
Single-pass type II membrane protein
Secreted
Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
Protein Attributes:
50:
MVTLRKRTLK | VLTFLVLFIF | LTSFFLNYSH | TMVATTWFPK | QMVLELSENL |
100:
KRLIKHRPCT | CTHCIGQRKL | SAWFDERFNQ | TMQPLLTAQN | ALLEDDTYRW |
150:
WLRLQREKKP | NNLNDTIKEL | FRVVPGNVDP | MLEKRSVGCR | RCAVVGNSGN |
200:
LRESSYGPEI | DSHDFVLRMN | KAPTAGFEAD | VGTKTTHHLV | YPESFRELGD |
250:
NVSMILVPFK | TIDLEWVVSA | ITTGTISHTY | IPVPAKIRVK | QDKILIYHPA |
300:
FIKYVFDNWL | QGHGRYPSTG | ILSVIFSMHV | CDEVDLYGFG | ADSKGNWHHY |
340:
WENNPSAGAF | RKTGVHDADF | ESNVTATLAS | INKIRIFKGR |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Chicken
Mouse
Pig
Human
ELISA Kit for Human Alpha 2,3-ST 1
ELISA Kit for Human Alpha 2,3-ST 1
ELISA Kit for Human Alpha 2,3-ST 1
ELISA Kit for Human Alpha 2,3-ST 1
CLIA Kit for Human Alpha 2,3-ST 1
CLIA Kit for Human Alpha 2,3-ST 1
CLIA Kit for Human Alpha 2,3-ST 1
CLIA Kit for Human Alpha 2,3-ST 1
Polyclonal Antibody for Human Alpha 2,3-ST 1
Polyclonal Antibody for Human Alpha 2,3-ST 1
Polyclonal Antibody for Human Alpha 2,3-ST 1
Polyclonal Antibody for Human Alpha 2,3-ST 1
Monoclonal Antibody for Human Alpha 2,3-ST 1
Monoclonal Antibody for Human Alpha 2,3-ST 1
Monoclonal Antibody for Human Alpha 2,3-ST 1
Monoclonal Antibody for Human Alpha 2,3-ST 1
Protein for Human Alpha 2,3-ST 1
Protein for Human Alpha 2,3-ST 1
Protein for Human Alpha 2,3-ST 1
Protein for Human Alpha 2,3-ST 1
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Placenta .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Submandibular gland .
3.
"Molecular cloning and expression of Galbeta1,3GalNAc alpha2, 3-sialyltransferase from human fetal liver."
Shang J.
,
Qiu R.
,
Wang J.
,
Liu J.
,
Zhou R.
,
Ding H.
,
Yang S.
,
Zhang S.
,
Jin C.
Eur. J. Biochem.265:580-588(1999)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Fetal liver .
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
tissue :
Skin .