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Index > Protein center > ST3GAL4(Gene name) > Human
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  • ST3GAL4 (Gene name),
  • CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4 (Protein name ),  SIA4C_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • 3D
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  • Predicted Eptitope
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  • Vaild Sequence
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  • Gene name:
    ST3GAL4(CGS23;NANTA3;SIAT4C;STZ);
    Protein name:
    CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 4(Alpha 2,3-ST 4;Beta-galactoside alpha-2,3-sialyltransferase 4);
    Alternative:
    Gal-NAc6S;Alpha 2,3-sialyltransferase IV;SAT-3;Gal-beta-1,4-GalNAc-alpha-2,3-sialyltransferase;ST3Gal IV(ST3GalIV);ST-4;STZ;ST3GalA.2;Sialyltransferase 4C(SIAT4-C);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    It may catalyze the formation of the NeuAc-alpha-2,3-Gal-beta-1,3-GalNAc- or NeuAc-alpha-2,3-Gal-beta-1,3-GlcNAc-sequences found in terminal carbohydrate groups of glycoproteins and glycolipids. It may be involved in the biosynthesis of the sialyl Lewis X determinant. Also acts on the corresponding 1,3-galactosyl derivative.
    Subcellular Location:
    Golgi apparatus Golgi stack membrane Single-pass type II membrane protein Secreted Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
    Protein Attributes:
    Sequence length:
    333
    Sequence:
    50:
    MVSKSRWKLL | AMLALVLVVM | VWYSISREDR | YIELFYFPIP | EKKEPCLQGE | 
    100:
    AESKASKLFG | NYSRDQPIFL | RLEDYFWVKT | PSAYELPYGT | KGSEDLLLRV | 
    150:
    LAITSSSIPK | NIQSLRCRRC | VVVGNGHRLR | NSSLGDAINK | YDVVIRLNNA | 
    200:
    PVAGYEGDVG | SKTTMRLFYP | ESAHFDPKVE | NNPDTLLVLV | AFKAMDFHWI | 
    250:
    ETILSDKKRV | RKGFWKQPPL | IWDVNPKQIR | ILNPFFMEIA | ADKLLSLPMQ | 
    300:
    QPRKIKQKPT | TGLLAITLAL | HLCDLVHIAG | FGYPDAYNKK | QTIHYYEQIT | 
    333:
    LKSMAGSGHN | VSQEALAIKR | MLEMGAIKNL | TSF
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    UniGene:
    String:
    Pfam:
    MIM:
    KEGG:
    SMR:
    Uniprot:
     
    FOR
    ELISA Kit for Human Alpha 2,3-ST 4
    ELISA Kit for Human Alpha 2,3-ST 4
    ELISA Kit for Human Alpha 2,3-ST 4
    CLIA Kit for Human Alpha 2,3-ST 4
    CLIA Kit for Human Alpha 2,3-ST 4
    CLIA Kit for Human Alpha 2,3-ST 4
    Polyclonal Antibody for Human Alpha 2,3-ST 4
    Polyclonal Antibody for Human Alpha 2,3-ST 4
    Polyclonal Antibody for Human Alpha 2,3-ST 4
    Monoclonal Antibody for Human Alpha 2,3-ST 4
    Monoclonal Antibody for Human Alpha 2,3-ST 4
    Monoclonal Antibody for Human Alpha 2,3-ST 4
    Protein for Human Alpha 2,3-ST 4
    Protein for Human Alpha 2,3-ST 4
    Protein for Human Alpha 2,3-ST 4

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    Precision
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    Recovery
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    Linearity
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    References
    1. 1.
      "Genomic organization and chromosomal mapping of the Gal beta 1,3GalNAc/Gal beta 1,4GlcNAc alpha 2,3-sialyltransferase."
      Kitagawa H. , Mattei M.-G. , Paulson J.C.
      J. Biol. Chem.271:931-938(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Placenta.
    2. 2.
      "Cloning of a novel alpha 2,3-sialyltransferase that sialylates glycoprotein and glycolipid carbohydrate groups."
      Kitagawa H. , Paulson J.C.
      J. Biol. Chem.269:1394-1401(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2)
      tissue: Placenta.
    3. 3.
      "Expression cloning of a novel Gal beta (1-3/1-4) GlcNAc alpha 2,3-sialyltransferase using lectin resistance selection."
      Sasaki K. , Watanabe E. , Kawashima K. , Sekine S. , Dohi T. , Oshima M. , Hanai N. , Nishi T. , Hasegawa M.
      J. Biol. Chem.268:22782-22787(1993) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 5)
    4. 4.
      "Identification of nine alternatively spliced alpha2,3-sialyltransferase, ST3Gal IV, transcripts and analysis of their expression by RT-PCR and laser-induced fluorescent capillary electrophoresis (LIF-CE) in twenty-one human tissues."
      Grahn A. , Larson G.
      Glycoconj. J.18:759-767(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 4; 6 AND 7);ALTERNATIVE SPLICING
      tissue: Peripheral blood leukocyte.
    5. 5.
      "Complete sequencing and characterization of 21,243 full-length human cDNAs."
      Ota T. , Suzuki Y. , Nishikawa T. , Otsuki T. , Sugiyama T. , Irie R. , Wakamatsu A. , Hayashi K. , Sato H. , Nagai K. , Kimura K. , Makita H. , Sekine M. , Obayashi M. , Nishi T. , Shibahara T. , Tanaka T. , Ishii S. , more...
      Nat. Genet.36:40-45(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 4)
      tissue: Placenta.
    6. 6.
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
    7. 7.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
      tissue: Placenta.
    8. 8.
      "Characterization of two glycolipid: alpha 2-3sialyltransferases, SAT-3 (CMP-NeuAc:nLcOse4Cer alpha 2-3sialyltransferase) and SAT-4 (CMP-NeuAc:GgOse4Cer alpha 2-3sialyltransferase), from human colon carcinoma (Colo 205) cell line."
      Basu S.S. , Basu M. , Li Z. , Basu S.
      Biochemistry35:5166-5174(1996) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 48-314;FUNCTION
      tissue: Colon carcinoma.
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