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Index > Protein center > ST8SIA2(Gene name) > Human
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  • ST8SIA2 (Gene name),
  • Alpha-2,8-sialyltransferase 8B (Protein name ),  SIA8B_HUMAN from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Predicted Eptitope
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  • Gene name:
    ST8SIA2(SIAT8B;STX);
    Protein name:
    Alpha-2,8-sialyltransferase 8B;
    Alternative:
    Sialyltransferase X(STX);Sialyltransferase 8B(SIAT8-B);Sialytransferase St8Sia II(ST8SiaII);
    Organism:
    Human (Homo sapiens). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    May transfer sialic acid through alpha-2,8-linkages to the alpha-2,3-linked and alpha-2,6-linked sialic acid of N-linked oligosaccharides of glycoproteins and may be involved in PSA (polysialic acid) expression.
    Subcellular Location:
    Golgi apparatus membrane Single-pass type II membrane protein
    Protein Attributes:
    Sequence length:
    375
    Sequence:
    50:
    MQLQFRSWML | AALTLLVVFL | IFADISEIEE | EIGNSGGRGT | IRSAVNSLHS | 
    100:
    KSNRAEVVIN | GSSSPAVVDR | SNESIKHNIQ | PASSKWRHNQ | TLSLRIRKQI | 
    150:
    LKFLDAEKDI | SVLKGTLKPG | DIIHYIFDRD | STMNVSQNLY | ELLPRTSPLK | 
    200:
    NKHFGTCAIV | GNSGVLLNSG | CGQEIDAHSF | VIRCNLAPVQ | EYARDVGLKT | 
    250:
    DLVTMNPSVI | QRAFEDLVNA | TWREKLLQRL | HSLNGSILWI | PAFMARGGKE | 
    300:
    RVEWVNELIL | KHHVNVRTAY | PSLRLLHAVR | GYWLTNKVHI | KRPTTGLLMY | 
    350:
    TLATRFCKQI | YLYGFWPFPL | DQNQNPVKYH | YYDSLKYGYT | SQASPHTMPL | 
    375:
    EFKALKSLHE | QGALKLTVGQ | CDGAT
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    Pfam:
    String:
    UniGene:
    SMR:
    MIM:
    KEGG:
    Uniprot:
     
    FOR
    ELISA Kit for Human Alpha-2,8-sialyltransferase 8B
    ELISA Kit for Human Alpha-2,8-sialyltransferase 8B
    ELISA Kit for Human Alpha-2,8-sialyltransferase 8B
    CLIA Kit for Human Alpha-2,8-sialyltransferase 8B
    CLIA Kit for Human Alpha-2,8-sialyltransferase 8B
    CLIA Kit for Human Alpha-2,8-sialyltransferase 8B
    Polyclonal Antibody for Human Alpha-2,8-sialyltransferase 8B
    Polyclonal Antibody for Human Alpha-2,8-sialyltransferase 8B
    Polyclonal Antibody for Human Alpha-2,8-sialyltransferase 8B
    Monoclonal Antibody for Human Alpha-2,8-sialyltransferase 8B
    Monoclonal Antibody for Human Alpha-2,8-sialyltransferase 8B
    Monoclonal Antibody for Human Alpha-2,8-sialyltransferase 8B
    Protein for Human Alpha-2,8-sialyltransferase 8B
    Protein for Human Alpha-2,8-sialyltransferase 8B
    Protein for Human Alpha-2,8-sialyltransferase 8B

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    Precision
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    Linearity
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    References
    1. 1.
      "A human STX cDNA confers polysialic acid expression in mammalian cells."
      Scheidegger E.P. , Sternberg L.R. , Roth J. , Lowe J.B.
      J. Biol. Chem.270:22685-22688(1995) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    2. 2.
      "Human STX polysialyltransferase forms the embryonic form of the neural cell adhesion molecule. Tissue-specific expression, neurite outgrowth, and chromosomal localization in comparison with another polysialyltransferase, PST."
      Angata K. , Nakayama J. , Fredette B. , Chong K. , Ranscht B. , Fukuda M.
      J. Biol. Chem.272:7182-7190(1997) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    3. 3.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
    4. 4.
      "Differential expression of five sialyltransferase genes in human tissues."
      Kitagawa H. , Paulson J.C.
      J. Biol. Chem.269:17872-17878(1994) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 154-375
      tissue: Fetal brain.
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